Enzyme-catalyzed transesterification of unusual substrate: Synthesis of acyclovir and L-ascorbic acid (vitamin C) vinyl esters

Chinese Chemical Letters

Volumn 14, Issue 2, 2003, Pages 163-166

  Xue, Xing Tao ^a   Lü, De Shui ^a   Chen, Zhi Chun ^a   Wu, Qi ^a   Cai, Ying ^a   Lin, Xian Fu ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Acyclovir; Alkaline protease; Lipase; Transesterification; Vinyl ester; Vitamin C

Indexed keywords

ACICLOVIR; ADIPIC ACID DERIVATIVE; ALKALINE PROTEINASE; ASCORBIC ACID; DIVINYLADIPATE; ESTER DERIVATIVE; ORGANIC SOLVENT; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; CATALYSIS; DRUG SYNTHESIS; MUCOR; TRANSESTERIFICATION;

EID: 0037297967     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. G. Arnold, Y. Milka, Y. Ivan, Int. Appl., WO 9851692 A1 19 NOV 1998, 70pp.
2. L. M. Beauchamp, G. F. Orr, et al., Antiviral Chem. Chemother., 1992, 3 (3), 157.
3. Y. C. Yan, U. T. Bornscheuer, R. D. Schmid, Biotechnol. Lett., 1999, 1051.
4. C. Humeau, B. Rovel, M. Girardin, Biotechnol. Lett., 2000, 165.
5. E. D. M John, W. S. Henry, J. P. Robert, 1960, Brit 827 718.
6. -1 (C=C).
7. H. W. Gao; A.K. Mitra, Magn. Reson. Chem., 1999, 37 (9), 687.
8. M. Kitagawa, H. Fan, T. Raku, et al., Biotechnol. Lett., 2000, 22, 883.
9. Q. Wu, D. S. Lu, X. F. Lin, Biotechnol. Lett., 2001, 23, 1981.
10. Q. Wu, J. Y. Feng, X. F. Lin, et al., Chin. Chem. Lett., 2002, 13 (5), 416.
11. -1 (C=C).