A comparison of the specificity and sensitivity of two Candida antigen assay systems for the diagnosis of deep candidiasis in patients with hematologic diseases

Medical Science Monitor

Volumn 9, Issue 2, 2003, Pages

  Misaki, Hirofumi ^a   Iwasaki, Hiromichi ^a   Ueda, Takanori ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Candida antigen; Candida infection; Deep candidiasis; Hematologic disease; Immunocompromised host

Indexed keywords

ADULT; ANTIBODY DETECTION; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANDIDA; CANDIDIASIS; CLINICAL ARTICLE; COMPARATIVE STUDY; DEVICE; DRUG EFFECT; EARLY DIAGNOSIS; FEMALE; HEMATOLOGIC DISEASE; HUMAN; IMMUNE DEFICIENCY; IMMUNOASSAY; LATEX AGGLUTINATION TEST; MALE;

ANTIGENS, FUNGAL; CANDIDA; CANDIDIASIS; FEMALE; HEMATOLOGIC DISEASES; HUMANS; LATEX FIXATION TESTS; MALE; MIDDLE AGED; SENSITIVITY AND SPECIFICITY;

EID: 0037297086     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Bodey GP: Fungal infections complicating acute leukemia. J Chronic Dis, 1966; 19: 667-687
2. Myerowitz RL, Pazin GJ, Allen CM: Disseminated candidiasis. Changes in incidence, underlying diseases, and pathology. Am J Clin Pathol, 1977; 68: 29-38
3. Winston DJ, Gale RP, Meyer DV, Young LS: Infectious complications of human bone marrow transplantation. Medicine, 1979; 58: 1-31
4. Javis WR: Epidemiology of nosocomial fungal infections, with emphasis on Candida species. Clin Infect Dis, 1995; 20: 1526-30
5. Pfaller MA: Nosocomial candidiasis: emerging species, reservoirs, and modes of transmission. Clin Infect Dis, 1996; 22: 89-94
6. Francoise MC, Timothy EK, Donald A: Fungemia in the immunocompromised host. Am J Med, 1981; 71: 363-70.
7. Martino P, Girmenia C, Venditti M et al: Candida colonization and systemic infection in neutropenic patients. A retrospective study. Cancer, 1989; 64: 2030-4
8. Lemieux C, St-Germain G, Vincelette J et al: Collaborative evaluation of antigen detection by a commercial latex agglutination test and enzyme immunoassay in the diagnosis of invasive candidiasis. J Clin Microbiol, 1990; 28: 249-53
9. Edwards JE Jr, Bodey GP, Bowden RA et al: International conference for the development of a consensus on the management and prevention of severe candidal infections. Clin Infect Dis, 1997; 25: 43-59
10. Richardson MD, Kokki MH: Antifungal therapy in 'bone marrow failure'. Br J Haematol, 1998; 100: 619-28
11. Meunier F: Fluconazole treatment of fungal infections in the immunocompromised host. Semin Oncol, 1990; 17(Suppl 6): 19-23
12. Guiot HF, Fibbe WE, Wout JW: Risk factors for fungal infection in patients with malignant hematologic disorders: implications for empirical therapy and prophylaxis. Clin Infect Dis, 1994; 18: 525-42
13. Klastersky J: Prevention and therapy of fungal infections in cancer patients: A review of recently published information. Support Care Cancer, 1995; 3: 393-401
14. Philpott-Howard J: Prophylaxis and therapy of infections in neutropenic patients. Curr Opin Infect Dis, 1996; 9: 218-22
15. Maksymiuck AW, Throngprosert S, Hopfer R et al: Systemic candidiasis in cancer patients. Am J Med, 1984; 77: 20-7
16. Horn RL, Wong B, Kiehn TE, Armstrong D: Fungemia in a cancer hospital: changing frequency, earlier onset, and results of therapy. Rev Infect Dis, 1985; 7: 646-55
17. Saral R: Candida and Aspergillus infections in immunocompromised patients: an overview. Rev Infect Dis, 1991; 13: 487-92
18. Reiss E, Morrison CJ: Nonculture methods for diagnosis of disseminated candidiasis. Clin Microbiol Rev, 1993; 6: 311-23
19. Mitsutake K, Miyazaki T, Tashiro T et al: Enolase antigen, mannan antigen, Cand-Tec antigen, and beta-glucan in patients with candidemia. J Clin Microbiol, 1996; 34: 1918-21
20. Gentry LO, Wilkinson ID, Lea AS, Price MF: Latex agglutination test for detection of Candida antigen in patients with disseminated disease. Eur J Clin Microbiol Infect Dis, 1983; 2: 122-8
21. Price MF, Gentry LO: Incidence and significance of Candida antigen in low-risk and high-risk patient populations. Eur J Clin Microbiol Infect Dis, 1986; 5: 416-9
22. Fung JC, Donta ST, Tilton RC: Candida detection system (Cand-Tec) to differentiate between Candida albicans colonization diseases. J Clin Microbiol, 1986; 24: 542-7
23. Burnie JP, Williams JD: Evaluation of the Ramco latex agglutination test in the early diagnosis of systemic candidiasis. Eur J Clin Microbiol Infect Dis, 1985; 4: 98-101
24. Bailey JW, Sada E, Brass C, Bennett JE: Diagnosis of systemic candidiasis by latex agglutination for serum antigen. J Clin Microbiol, 1985; 21: 749-52
25. Kahn FW, Jones JM: Latex agglutination tests for the detection of Candida antigens in sera of patients with invasive candidiasis. J Infect Dis, 1986; 153: 579-85
26. Ness MJ, Vaughan VP, Woods GL: Candida antigen latex test for detection of invasive candidiasis in immunocompromised patients. J Infect Dis, 1989; 159: 495-502
27. Sanchez ML, Pfaller MA, Cabezudo I et al: Diagnosis of disseminated candidiasis in hospitalized patients using the Cand-Tec latex agglutination assay. Mycopathologia, 1992; 118: 153-62
28. Pallavicini F, Izzi I, Pennisi MA et al: Evaluation of the utility of serological tests in the diagnosis of candidemia. Minerva Anestesiol, 1999; 65: 637-9
29. Bar W, Hecker H: Diagnosis of systemic Candida infections in patients of the intensive care unit. Significance of serum antigens and antibodies. Mycosis, 2002; 45: 22-28
30. Phillip P, Dowd A, Jewesson P: Nonvalue of antigen detection immunoassays for diagnosis ofcandidemia. J Clin Microbiol, 1990; 28: 2320-2326
31. Iwasaki H, Ueda T, Nakayama T et al: A new diagnostic aid for deep mycosis associated with hematologic disease using (13) - D-glucan assay (G-test). In: Recent advances in chemotherapy. American Society for Microbiology, Washington DC, 1993; 705-6
32. Galen RS, Gambino SR: Beyond normality in the predictive value in medical diagnosis. John Wiley and Sons, New York, 1975; 10-97
33. Iwasaki H, Misaki H, Nakamura T, Ueda T: The surveillance of the serum Candida antigen titer for the initiation of antifungal therapy after post-remission chemotherapy in patients with acute leukemia. Int J Hematol, 2000; 71: 266-72
34. Herent P, Stynen D, Hernando F et al: Retrospective evaluation of two latex agglutination tests for detection of circulating antigens during invasive candidosis. J Clin Microbiol, 1992; 30: 2158-64
35. Cabezudo I, Pfaller M, Gerarden T et al: Value of Cand-Tec Candida antigen assay in the diagnosis and therapy of systemic can-call-didiasis in high-risk patients. Eur J Clin Microbiol Infect Dis, 1989; 8: 770-7
36. Drutz DJ: Controversies in the diagnosis and management of infectious diseases. Session: Fungal infections. Summary and Discussion. Rev Infect Dis, 1987; 9: 417-20
37. Greenfield RA, Troutt DL, Rickard RC, Altmiller DH: Comparison of antibody, antigen, and metabolite assays in rat models of systemic and gastrointestinal candidiasis. J Clin Microbiol, 1988; 26: 409-17
38. Mitsuya M, Wada K, Makimura K, Yamaguchi H: The antigen (CAND-TEC antigen) detected by CAND-TEC test for diagnosis of candidiasis. Rinsho Byori, 1996; 44: 512-7
39. D'Antonio D, Iacone A, Schioppa FS et al: Effect of the current antimicrobial therapeutic strategy on fungal colonization in patients with hematologic malignancies. Curr Microbiol, 1996; 33: 118-2