Cytotoxic T lymphocyte monitoring in steroid-free immunosuppression

Pediatric Transplantation

Volumn 7, Issue 1, 2003, Pages 4-6

  Strehlau, Juergen ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; CYCLOSPORIN; DEXAMETHASONE; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID;

CELL FUNCTION; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DISEASE MARKER; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; EDITORIAL; GENE EXPRESSION REGULATION; GRAFT SURVIVAL; HISTOPATHOLOGY; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MEDICAL DECISION MAKING;

ACUTE DISEASE; GENE EXPRESSION; GRAFT REJECTION; GRANZYMES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0037293559     PISSN: 13973142     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3046.2003.2e073.x     Document Type: Editorial

References (6)

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2. VASCONCELLOS LM, SCHACHTER AD, ZHENG XX et al. Cytotoxic lymphocyte gene expression in peripheral blood leukocytes correlates with rejecting renal allografts. Transplantation 1998; 66: 562-566.
3. CHAE DW, NOSAKA Y, STROM TB, MASLINSKI W. Distribution of IL-15 receptor alpha-chains on human peripheral blood mononuclear cells and effect of immunosuppressive drugs on receptor expression. J Immunol 1996; 157: 2813-5819.
4. NG WF, DUGGAN PJ, PONCHEL F, et al. Human CD4(+) CD25(+) cells: a naturally occurring population of regulatory T cells. Blood 2001; 98: 2736-2744.
5. GREGORI S, CASORATI M, AMUCHASTEGUI S, SMIROLDO S, DAVALLI AM, ADORINI L. Regulatory T cells induced by 1 alpha, 25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 2001; 167: 1945-1953.
6. LI B, HARTONO C, DING R, SHARMA VK, et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med 2001; 344: 947-954.