The beneficial effects of the anabolic steroid oxandrolone in the geriatric burn population

Wounds

Volumn 15, Issue 2, 2003, Pages 54-58

  Demling, Robert ^a   DeSanti, Leslie ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANABOLIC AGENT; NITROGEN; OXANDROLONE;

AGED; AGING; ARTICLE; BURN; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DONOR SITE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; HOSPITALIZATION; HUMAN; MALE; NITROGEN BALANCE; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL; SKIN TRANSPLANTATION; SURVIVAL; TREATMENT OUTCOME; WEIGHT REDUCTION; WOUND HEALING;

EID: 0037291970     PISSN: 10447946     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. O'Neill A, Rabbit A, Hamel H, Yurt R. Burns in the elderly: Our burn centers' experience with patients over 75 years old. J Burn Care Rehab 2000;21:183.
2. Kravitz M, Elliott S, Weissman M, et al. Thermal injury in the elderly: Incidence and cause. J Burn Care Rehab 198;6:487-9.
3. Saffle J, Davis B, Williams P. Recent outcomes in the treatment of burn injury in the United States: A report from the American Burn Association Patient Registry. J Burn Care Rehab 1995;16:219-32.
4. Goldstein S. The biology of aging. N Engl J Med 1977;288:1120-9.
5. Mira L. Senescence and the pathology of aging. Med Lab Sci 1992;47:871-80.
6. Kannel W. Nutrition and the occurrence and prevention of cardiovascular disease in the elderly. Nutr Rev 1988;46:68-81.
7. Wallace J, Schwartz R. Involuntary weight loss in older patients: Incidence and clinical significance. J Am Geriatric Soc 1975;43:229-37.
8. Forbes GB. Body composition: Influence of nutrition, disease, growth, and aging. In: Shils ME, Olson JA, Shike M (eds). Modern Nutrition in Health and Disease. Philadelphia, PA: Lea & Febiger, 1994;781-801.
9. Evans WJ, Campbell W. Sarcopenia and age related changes in body composition and functional capacity. J Nutr 1993;123:465-8.
10. Demling R, DeSanti L. The rate of restoration of lean mass after burn injury using the anabolic agent oxandrolone is not age dependent. Burns 2001;27:46-52.
11. Rudman D. Growth hormone body composition and aging. Am Geriatr Soc 1985;33:800-7.
12. Gherondacke C, Dowling W, Pincus G. Metabolic changes induced in elderly patients with an anabolic steroid (oxandrolone). Am Geriatr Soc 1991;42:751-5.
13. Fratianni R, Brandt C. Improved survival of adults with extensive burns. J Burn Care Rehab 1997;18:347-51.
14. Hart D, Wolf S, Herndon D, et al. Determinants of skeletal muscle catabolism after severe burn. Ann Surg 2000;232:455-65.
15. Demling R. Comparison of the anabolic effects and complications of human growth hormone and the testosterone analog after severe burn injury. Burns 1999;25:215-21.