Anthracyclines in Nijmegen breakage syndrome

Medical and Pediatric Oncology

Volumn 40, Issue 2, 2003, Pages 122-124

  Barth, Elsa ^a   Demori, Eliana ^a   Pecile, Vanna ^a   Zanazzo, Giulio Andrea ^a   Malorgio, Cristiana ^a   Tamaro, Paolo ^a  

^a INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

Author keywords

Anthracycline induced cardiomyopathy; Chemotoxicity; Chromosomal instability; Hypersensitivity to chemotherapy; Nijmegen breakage syndrome (NBS); Radiation hypersensitivity

Indexed keywords

ANTHRACYCLINE; DAUNORUBICIN; DOXORUBICIN;

ACUTE GRANULOCYTIC LEUKEMIA; AUTOSOMAL RECESSIVE DISORDER; BONE MARROW APLASIA; CANCER SUSCEPTIBILITY; CARDIOMYOPATHY; CARDIOTOXICITY; CASE REPORT; CHROMOSOME ANALYSIS; CHROMOSOME MUTATION; CHROMOSOME REARRANGEMENT; CLINICAL FEATURE; CONFERENCE PAPER; DNA REPAIR; DRUG TOLERABILITY; ECHOCARDIOGRAPHY; FACE DYSMORPHIA; FEMALE; HEART FAILURE; HUMAN; KARYOTYPE; LEUKEMIA REMISSION; LYMPHADENOPATHY; MICROCEPHALY; NIJMEGEN BREAKAGE SYNDROME; PRIORITY JOURNAL; SCHOOL CHILD;

ANTIBIOTICS, ANTINEOPLASTIC; CHILD; CHROMOSOME BREAKAGE; COMMON VARIABLE IMMUNODEFICIENCY; CRANIOFACIAL ABNORMALITIES; DAUNORUBICIN; DOXORUBICIN; FEMALE; GROWTH DISORDERS; HUMANS; SYNDROME;

EID: 0037291524     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/mpo.10079     Document Type: Conference Paper

References (16)

1. Barbi G, Scheres JMJC, Schindler D, et al. Chromosome instability and X-ray hypersensitivity in a microcephalic and growth-retarded child. Am J Med Genet 1991;40:44-50.
2. Chrzanowska KH, Kleijer WJ, Krajewska-Walasek M, et al. Eleven Polish patients with microcephaly, immunodeficiency and chromosomal instability; the Nijmegen breakage syndrome. Am J Med Genet 1995;57:462-471.
3. The International Nijmegen Breakage Syndrome Study Group. Nijmegen breakage syndrome. Arch Dis Child 2000;82:400-406.
4. Shiloh Y. Ataxia-teleangiectasia and the Nijmegen breakage syndrome: Related disorders but genes apart. Ann Rev Genet 1997;31:635-662.
5. Matsuura S, Weemaes C, Smeets D, et al. Genetic mapping using microcell-mediated chromosome transfer suggests a locus for Nijmegen breakage syndrome at chromosome 8q21-24. Am J Hum Genet 1997;60:1487-1494.
6. Saar K, Chrzanowska KH, Stumm M, et al. The gene for the ataxiateleangiectasia variant, Nijmegen breakage syndrome, maps to a 1-cM interval on chromosome 8q21. Am J Hum Genet 1997;60:605-610.
7. Van de Kaa CA, Weemaes CMR, Wesseling P, et al. Postmortem findings in the Nijmegen breakage syndrome. Pediatr Pathol 1994;14:787-796.
8. Babilon RW, Soprano KJ, Henderson EE. Hypersensitivity and reduced inhibition of DNA synthesis in ataxia teleangiectasia lymphoblasts treated with low levels of neocarzinostatin. Mutat Res 1985;146:79-87.
9. Antoccia A, Ricordy R, Maraschio P, et al. Chromosomal sensitivity to clastogenic agents and cell cycle perturbations in Nijmegen breakage syndrome lymphoblastoid cell lines. Int J Radiat Biol 1997;71:41-49.
10. Seidemann K, Henze G, Beck JD, et al. Non-Hodgkin's lymphoma in pediatric patients with chromosomal breakage syndromes (AT and NBS): Experience from the BFM trials. Ann Oncol 2000;11(Suppl 1):141-145.
11. Lipshultz SE, Lipsitz SR, Mone SM, et al. Female sex and higher drug dose as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer. N Engl J Med 1995;332:1738-1743.
12. Singal PK, Iliskovic N, et al. Doxorubicin-induced cardiomyopathy. N Engl J Med 1998;339:900-904.
13. Myers CE, McGuire WP, Liss RH, et al. Adriamycin: The role of lipid peroxidation in cardiac toxicity and tumor response. Science 1987;197:165-167.
14. Akman SA, Doroshow JH, Burke TG, et al. DNA base modifications induced in isolated human chromatin by NADH dehydrogenase-catalyzed reduction of doxorubicin. Biochemistry 1992;31:3500-3506.
15. Hemnani T, Parihar MS. Reactive oxygen species and oxidative DNA damage. Indian J Physiol Pharmacol 1998;42:440-452.
16. Ohshima H, Gilibert I, Bianchini F. Induction of DNA strand breakage and base oxidation by nitroxyl anion radical production. Free Radic Biol Med 1999;26:1305-1313.