메뉴 건너뛰기




Volumn 96, Issue 2, 2003, Pages 91-102

Clinical advances in therapies targeting the interleukin-2 receptor

Author keywords

[No Author keywords available]

Indexed keywords

BASILIXIMAB; CYCLOSPORIN; DACLIZUMAB; DENILEUKIN DIFTITOX; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR ANTIBODY; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NEUTRALIZING ANTIBODY; PREDNISOLONE; PROTEIN ANTIBODY; RECOMBINANT INTERLEUKIN 2; TAC ANTIBODY FV PE38; UNCLASSIFIED DRUG; ZENAPEX;

EID: 0037291111     PISSN: 14602725     EISSN: None     Source Type: Journal    
DOI: 10.1093/qjmed/hcg014     Document Type: Review
Times cited : (61)

References (86)
  • 1
    • 0017199306 scopus 로고
    • Selective in vitro growth of T-lymphocytes from human bone marrow
    • Morgan DA, Ruscetti FW, Gallo RC. Selective in vitro growth of T-lymphocytes from human bone marrow. Science 1976; 193:1007-8.
    • (1976) Science , vol.193 , pp. 1007-1008
    • Morgan, D.A.1    Ruscetti, F.W.2    Gallo, R.C.3
  • 2
    • 0023605142 scopus 로고
    • Three-dimensional structure of IL-2
    • Brandhuber BJ, Boone T. Three-dimensional structure of IL-2. Science 1987; 238:1707-9.
    • (1987) Science , vol.238 , pp. 1707-1709
    • Brandhuber, B.J.1    Boone, T.2
  • 3
    • 0025339511 scopus 로고
    • A cell culture model for T lymphocyte clonal anergy
    • Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990; 248:1349-6.
    • (1990) Science , vol.248 , pp. 1349-1356
    • Schwartz, R.H.1
  • 4
    • 0019230964 scopus 로고
    • T-cell growth factor
    • Smith KA. T-cell growth factor. Immunol Rev 1980; 51:337-57.
    • (1980) Immunol. Rev. , vol.51 , pp. 337-357
    • Smith, K.A.1
  • 5
    • 0019787148 scopus 로고
    • T cell growth factor receptors: Quantitation, specific and biological relevance
    • Robb RJ, Munck A, Smith KA. T cell growth factor receptors: quantitation, specific and biological relevance. J Exp Med 1981; 154:1455-74.
    • (1981) J. Exp. Med. , vol.154 , pp. 1455-1474
    • Robb, R.J.1    Munck, A.2    Smith, K.A.3
  • 6
    • 0019445921 scopus 로고
    • A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T-cells
    • Uchiyama T, Nelson DL, Fleisher TA, Waldmann TA. A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T-cells. J Immunol 1981; 126:1398-403.
    • (1981) J. Immunol. , vol.126 , pp. 1398-1403
    • Uchiyama, T.1    Nelson, D.L.2    Fleisher, T.A.3    Waldmann, T.A.4
  • 8
    • 0022908286 scopus 로고
    • Demonstration of a new (non-Tac) peptide that binds interleukin-2: A potential participant in a multichain interleukin-2 complex
    • Tsudo M, Kozak RW, Goldman CK, Waldmann TA. Demonstration of a new (non-Tac) peptide that binds interleukin-2: a potential participant in a multichain interleukin-2 complex. Proc Natl Acad Sci USA 1986; 83:9694-8.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9694-9698
    • Tsudo, M.1    Kozak, R.W.2    Goldman, C.K.3    Waldmann, T.A.4
  • 10
    • 0033491981 scopus 로고    scopus 로고
    • Biology of the interleukin-2 receptor
    • Nelson BH, Willerford DM. Biology of the interleukin-2 receptor. Adv Immunol 1998; 70:1-81.
    • (1998) Adv. Immunol. , vol.70 , pp. 1-81
    • Nelson, B.H.1    Willerford, D.M.2
  • 12
    • 0024349603 scopus 로고
    • The interleukin-2 receptor
    • Waldmann TA. The interleukin-2 receptor. Ann Rev Biochem 1989; 58:875-911.
    • (1989) Ann. Rev. Biochem. , vol.58 , pp. 875-911
    • Waldmann, T.A.1
  • 13
    • 85069011426 scopus 로고
    • Functional characterisation of the human interleukin-15 receptor alpha chain and close linkage of IL-15RA and IL-2RA genes
    • Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, et al. Functional characterisation of the human interleukin-15 receptor alpha chain and close linkage of IL-15RA and IL-2RA genes. J Biol Chem 1995; 270:29 862-9.
    • (1995) J. Biol. Chem. , vol.270 , Issue.29 , pp. 862-869
    • Anderson, D.M.1    Kumaki, S.2    Ahdieh, M.3    Bertles, J.4    Tometsko, M.5    Loomis, A.6
  • 14
    • 0025138985 scopus 로고
    • Delineation of an enhancerlike positive regulatory element in the interleukin-2 receptor alpha-chain gene
    • Lin BB, Cross SL, Halden NF, Roman DG, Toledano MB, et al. Delineation of an enhancerlike positive regulatory element in the interleukin-2 receptor alpha-chain gene. Mol Cell Biol 1990; 10:850-3.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 850-853
    • Lin, B.B.1    Cross, S.L.2    Halden, N.F.3    Roman, D.G.4    Toledano, M.B.5
  • 15
    • 0025292238 scopus 로고
    • The human interleukin-2 receptor beta-chain gene: Genomic organization, promoter analysis and chromosomal assignment
    • Shibuya H, Yoneyama M, Nakamura Y, Harada H, Hatakeyama M, et al. The human interleukin-2 receptor beta-chain gene: genomic organization, promoter analysis and chromosomal assignment. Nucleic Acids Res 1990; 18:3697-703.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3697-3703
    • Shibuya, H.1    Yoneyama, M.2    Nakamura, Y.3    Harada, H.4    Hatakeyama, M.5
  • 16
    • 0027379585 scopus 로고
    • Characterization of the human interleukin-2 receptor gamma chain gene
    • Noguchi M, Adelstein S, Cao X, Leonard WJ. Characterization of the human interleukin-2 receptor gamma chain gene. J Biol Chem 1993; 268:13601-8.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13601-13608
    • Noguchi, M.1    Adelstein, S.2    Cao, X.3    Leonard, W.J.4
  • 17
    • 0028183408 scopus 로고
    • The molecular basis of X-linked severe combined immunodeficiency: The role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c
    • Leonard WJ, Noguchi M, Russell SM, McBride OW. The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c. Immunol Rev 1994; 138:61-86.
    • (1994) Immunol. Rev. , vol.138 , pp. 61-86
    • Leonard, W.J.1    Noguchi, M.2    Russell, S.M.3    McBride, O.W.4
  • 18
    • 0028363377 scopus 로고
    • The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
    • Bamford RN, Grant AJ, Burton JD, Peters C, Kurys G, et al. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci USA 1994; 91:4940-4.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4940-4944
    • Bamford, R.N.1    Grant, A.J.2    Burton, J.D.3    Peters, C.4    Kurys, G.5
  • 19
    • 0030889207 scopus 로고    scopus 로고
    • The IFN-gamma receptor: A paradigm for cytokine receptor signalling
    • Bach EA, Aguet M, Schreiber RD. The IFN-gamma receptor: a paradigm for cytokine receptor signalling. Ann Rev Immunol 1997; 15:563-93.
    • (1997) Ann. Rev. Immunol. , vol.15 , pp. 563-593
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 20
    • 0034657396 scopus 로고    scopus 로고
    • The role of Stat5a and Stat5b in signalling by the IL-2 family cytokines
    • Lin JX, Leonard WJ. The role of Stat5a and Stat5b in signalling by the IL-2 family cytokines. Oncogene 2000; 19:2566-76.
    • (2000) Oncogene , vol.19 , pp. 2566-2576
    • Lin, J.X.1    Leonard, W.J.2
  • 21
    • 0025848163 scopus 로고
    • Interaction of the IL-2 receptor with the src-family kinase p56lck
    • Hatakeyama M, Kono T, Kobayashi N, Kawahara A, Levin SD, et al. Interaction of the IL-2 receptor with the src-family kinase p56lck. Science 1991; 252:1523-8.
    • (1991) Science , vol.252 , pp. 1523-1528
    • Hatakeyama, M.1    Kono, T.2    Kobayashi, N.3    Kawahara, A.4    Levin, S.D.5
  • 22
    • 0027278222 scopus 로고
    • Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor
    • Kobayashi N, Kono T, Hatakeyama M. Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor. Proc Natl Acad Sci USA 1993; 90:4201-5.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4201-4205
    • Kobayashi, N.1    Kono, T.2    Hatakeyama, M.3
  • 23
    • 0026091203 scopus 로고
    • IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase
    • Merida I, Diez E, Gaulton GN. IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase. J Immunol 1991; 147:2202-7.
    • (1991) J. Immunol. , vol.147 , pp. 2202-2207
    • Merida, I.1    Diez, E.2    Gaulton, G.N.3
  • 24
    • 0026721092 scopus 로고
    • Rapamycin selectively inhibits interleukin activation of p70 S6 kinase
    • Kuo CJ, Chung J, Florentino DF, Flanagan WM, Blenis J, et al. Rapamycin selectively inhibits interleukin activation of p70 S6 kinase. Nature 1992; 358:70-3.
    • (1992) Nature , vol.358 , pp. 70-73
    • Kuo, C.J.1    Chung, J.2    Florentino, D.F.3    Flanagan, W.M.4    Blenis, J.5
  • 25
    • 0026582203 scopus 로고
    • The growth factor IL-2 activates p21 ras proteins in normal human T-lymphocytes
    • Graves JD, Downward J, Izquierdo-Pastor M, Rayter S, Warne PH, et al. The growth factor IL-2 activates p21 ras proteins in normal human T-lymphocytes. J Immunol 1992; 148:2417-22.
    • (1992) J. Immunol. , vol.148 , pp. 2417-2422
    • Graves, J.D.1    Downward, J.2    Izquierdo-Pastor, M.3    Rayter, S.4    Warne, P.H.5
  • 27
    • 0029150110 scopus 로고
    • Immunologic self tolerance maintained by activated T-cells expressing IL-2 receptor alpha chains
    • Sakaguchi S, Sakaguchi N, Asano M, et al. Immunologic self tolerance maintained by activated T-cells expressing IL-2 receptor alpha chains. J Immunol 1995; 155:1151-64.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3
  • 28
    • 0022536230 scopus 로고
    • The structure, function and expression of interleukin-2 receptors on normal and malignant T-cells
    • Waldmann TA. The structure, function and expression of interleukin-2 receptors on normal and malignant T-cells. Science 1986; 232:727-32.
    • (1986) Science , vol.232 , pp. 727-732
    • Waldmann, T.A.1
  • 29
    • 0033491981 scopus 로고    scopus 로고
    • Biology of the interleukin-2 receptor
    • Nelson BH, Willerford DM. Biology of the interleukin-2 receptor. Adv Immunol 1998; 70:1-81.
    • (1998) Adv. Immunol. , vol.70 , pp. 1-81
    • Nelson, B.H.1    Willerford, D.M.2
  • 30
    • 0025778240 scopus 로고
    • The interleukin-2 receptor
    • Waldmann TA. The interleukin-2 receptor. J Biol Chem 1991; 266:2681-4.
    • (1991) J. Biol. Chem. , vol.266 , pp. 2681-2684
    • Waldmann, T.A.1
  • 31
    • 0013195631 scopus 로고    scopus 로고
    • IL-2 and IL-4 double knockout mice reject islet allografts: A role for novel T cell growth factors in allograft rejection
    • Li XC, Roy-Chaudhury P, Hancock WW, et al. IL-2 and IL-4 double knockout mice reject islet allografts: a role for novel T cell growth factors in allograft rejection. J Immunol 1998; 161:890-6.
    • (1998) J. Immunol. , vol.161 , pp. 890-896
    • Li, X.C.1    Roy-Chaudhury, P.2    Hancock, W.W.3
  • 32
    • 0032989065 scopus 로고    scopus 로고
    • Immunosuppression through inhibition of interleukin-2/interleukin-2 receptor interaction
    • Soulillou JP. Immunosuppression through inhibition of interleukin-2/interleukin-2 receptor interaction. Transplant Proc 1999; 31(Suppl.):49-51S.
    • (1999) Transplant Proc. , vol.31 , Issue.SUPPL.
    • Soulillou, J.P.1
  • 35
    • 0033571515 scopus 로고    scopus 로고
    • The new generation anti-CD25 monoclonal antbodies
    • Williams KA, Thiel M, Zola H. The new generation anti-CD25 monoclonal antbodies. Transplantation 1999; 68:1228-9.
    • (1999) Transplantation , vol.68 , pp. 1228-1229
    • Williams, K.A.1    Thiel, M.2    Zola, H.3
  • 37
    • 0011736580 scopus 로고
    • Bismuth-212-labeled anti-Tac monoclonal antibody: Alpha-particle-emitting radionuclides as modalities for radioimmunotherapy
    • Kozak RW, Atcher RW, Gansow OA, Friedmann AM, Hines JJ, et al. Bismuth-212-labeled anti-Tac monoclonal antibody: alpha-particle-emitting radionuclides as modalities for radioimmunotherapy. Proc Natl Acad Sci 1986; 83:474-8.
    • (1986) Proc. Natl. Acad. Sci. , vol.83 , pp. 474-478
    • Kozak, R.W.1    Atcher, R.W.2    Gansow, O.A.3    Friedmann, A.M.4    Hines, J.J.5
  • 38
    • 0028057249 scopus 로고
    • Recombinant immunotoxins containing anti-Tac (Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor expressing human carcinoma
    • Kreitman RJ, Bailon P, Chaudhary VK, Fitzgerald DJP, Pastan I. Recombinant immunotoxins containing anti-Tac (Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor expressing human carcinoma. Blood 1994; 83:426.
    • (1994) Blood , vol.83 , pp. 426
    • Kreitman, R.J.1    Bailon, P.2    Chaudhary, V.K.3    Fitzgerald, D.J.P.4    Pastan, I.5
  • 39
    • 0023657391 scopus 로고
    • Functional domains of pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli
    • Hwang J, Fitzgerald DT, Adhyas S, Pastan I. Functional domains of pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli. Cell 1987; 48:129-36.
    • (1987) Cell , vol.48 , pp. 129-136
    • Hwang, J.1    Fitzgerald, D.T.2    Adhyas, S.3    Pastan, I.4
  • 40
    • 0001776198 scopus 로고    scopus 로고
    • DAB(389)IL-2 (ONTAK): A new fusion protein technology
    • Foss FM. DAB(389)IL-2 (ONTAK) : a new fusion protein technology. Clin Lymphoma 2000; (Suppl. 1):S27-31.
    • (2000) Clin. Lymphoma. , Issue.SUPPL. 1
    • Foss, F.M.1
  • 41
    • 0019254359 scopus 로고
    • Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
    • Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA 1980; 77:7415-19.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 7415-7419
    • Poiesz, B.J.1    Ruscetti, F.W.2    Gazdar, A.F.3    Bunn, P.A.4    Minna, J.D.5
  • 42
    • 0021990233 scopus 로고
    • Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells
    • Uchiyama T, Hori T, Tsudo M, Wano Y, Umadome H, et al. Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells. J Clin Invest 1985; 76:446-53.
    • (1985) J. Clin. Invest. , vol.76 , pp. 446-453
    • Uchiyama, T.1    Hori, T.2    Tsudo, M.3    Wano, Y.4    Umadome, H.5
  • 43
    • 85184969570 scopus 로고
    • The IL-2 eceptor:A target for monoclonal antibody therapy of HTLV-1 induced adult T-cell leukaemia
    • Waldmann TA, White JD, Goldmann CK. The IL-2 receptor:a target for monoclonal antibody therapy of HTLV-1 induced adult T-cell leukaemia. Blood 1993; 82:1701-12.
    • (1993) Blood , vol.82 , pp. 1701-1712
    • Waldmann, T.A.1    White, J.D.2    Goldmann, C.K.3
  • 44
    • 0028840870 scopus 로고
    • Radioimmunotherapy of IL-2 receptor alpha-expressing Adult T-cell leukaemia with Yttrium-90 labelled anti-Tac
    • Waldmann TA, White JD, Carrasquillo JA, Reynolds JC, Park CH, et al. Radioimmunotherapy of IL-2 receptor alpha-expressing Adult T-cell leukaemia with Yttrium-90 labelled anti-Tac. Blood 1995; 86:4063-75.
    • (1995) Blood , vol.86 , pp. 4063-4075
    • Waldmann, T.A.1    White, J.D.2    Carrasquillo, J.A.3    Reynolds, J.C.4    Park, C.H.5
  • 45
    • 0033764673 scopus 로고    scopus 로고
    • Advances in Interleukin-2 receptor targeted treatment
    • Morris JC, Waldmann TA. Advances in Interleukin-2 receptor targeted treatment. Ann Rheum Dis 2000; 59(Suppl.):i109-14.
    • (2000) Ann. Rheum. Dis. , vol.59 , Issue.SUPPL.
    • Morris, J.C.1    Waldmann, T.A.2
  • 46
    • 0034001076 scopus 로고    scopus 로고
    • Phase 1 trial of recombinant immunotoxin anti-Tac Fv-PE38 in patients with haematologic malignancies
    • Kreitman RJ, Wilson WH, White JD, Jaffe ES, Giardina S. Phase 1 trial of recombinant immunotoxin anti-Tac Fv-PE38 in patients with haematologic malignancies. J Clin Oncol 2000; 18:1622-36.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1622-1636
    • Kreitman, R.J.1    Wilson, W.H.2    White, J.D.3    Jaffe, E.S.4    Giardina, S.5
  • 48
    • 0035863468 scopus 로고    scopus 로고
    • Pivotal phase III trial of two dose levels of denileukin diftitox for the treatment of cutaneous T-cell lymphoma
    • Olsen E, Duvic M, Frankel A, Kim Y, Martin A, et al. Pivotal phase III trial of two dose levels of denileukin diftitox for the treatment of cutaneous T-cell lymphoma. J Clin Oncol 2001; 19:376-88.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 376-388
    • Olsen, E.1    Duvic, M.2    Frankel, A.3    Kim, Y.4    Martin, A.5
  • 49
    • 0036222389 scopus 로고    scopus 로고
    • Quality-of-life improvements in cutaneous T-cell lymphoma patients treated with denileukin diftitox
    • Duvic M, Kuzel TM, Olsen EA, Martin AG, Foss FM, et al. Quality-of-life improvements in cutaneous T-cell lymphoma patients treated with denileukin diftitox. Clin Lymphoma 2002; 4:222-8.
    • (2002) Clin. Lymphoma , vol.4 , pp. 222-228
    • Duvic, M.1    Kuzel, T.M.2    Olsen, E.A.3    Martin, A.G.4    Foss, F.M.5
  • 50
    • 13044311376 scopus 로고    scopus 로고
    • Treatment of non-infectious intermediate and posterior uveitis with the humanized anti-Tac monoclonal antibody: A phase I/II clinical trial
    • Nussenblatt RB, Fortin E, Schiffman R, Rizzon L, Smith J, et al. Treatment of non-infectious intermediate and posterior uveitis with the humanized anti-Tac monoclonal antibody: a phase I/II clinical trial. Proc Natl Acad Sci USA 1999; 96:7462-6.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7462-7466
    • Nussenblatt, R.B.1    Fortin, E.2    Schiffman, R.3    Rizzon, L.4    Smith, J.5
  • 51
    • 0030641530 scopus 로고    scopus 로고
    • Humanized antibodies against the alpha-chain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases
    • Guex-Crosier Y, Raber J, Chan CC, Knete MS, Benichou J. Humanized antibodies against the alpha-chain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases. J Immunol 1997; 158:452-8.
    • (1997) J. Immunol. , vol.158 , pp. 452-458
    • Guex-Crosier, Y.1    Raber, J.2    Chan, C.C.3    Knete, M.S.4    Benichou, J.5
  • 52
    • 0027956688 scopus 로고
    • Treatment of acute Graft-versus-host disease with humanized anti-Tac
    • Anasetti C, Hansen JA, Waldmann TA. Treatment of acute Graft-versus-host disease with humanized anti-Tac. Blood 1994; 84:1320-7.
    • (1994) Blood , vol.84 , pp. 1320-1327
    • Anasetti, C.1    Hansen, J.A.2    Waldmann, T.A.3
  • 53
    • 0033964862 scopus 로고    scopus 로고
    • Daclizumab, a humanized anti-IL-2 receptor alpha chain antibody for treatment of acute graft-versus-host disease
    • Przepiorka D, Kernan NA, Ippoliti C, Pappadopoulous EB, Giralt S, et al. Daclizumab, a humanized anti-IL-2 receptor alpha chain antibody for treatment of acute graft-versus-host disease. Blood 2000; 95:83-9.
    • (2000) Blood , vol.95 , pp. 83-89
    • Przepiorka, D.1    Kernan, N.A.2    Ippoliti, C.3    Pappadopoulous, E.B.4    Giralt, S.5
  • 54
    • 0033857240 scopus 로고    scopus 로고
    • Successful in vivo blockade of CD25 on T-cells by administration of humanized anti-Tac antibody to patients with psoriasis
    • Kreuger JG, Walters IB, Myazawa M, Gilleaudeau P, Hakimi J, et al. Successful in vivo blockade of CD25 on T-cells by administration of humanized anti-Tac antibody to patients with psoriasis. J Am Acad Dermatol 2000; 43:448-58.
    • (2000) J. Am. Acad. Dermatol. , vol.43 , pp. 448-458
    • Kreuger, J.G.1    Walters, I.B.2    Myazawa, M.3    Gilleaudeau, P.4    Hakimi, J.5
  • 55
    • 0034074077 scopus 로고    scopus 로고
    • Successful treatment of severe psoriasis with basiliximab, an IL-2 receptor monoclonal antibody
    • Owen CM, Harrison PV. Successful treatment of severe psoriasis with basiliximab, an IL-2 receptor monoclonal antibody. Clin Exp Dermatol 2000; 25:195-7.
    • (2000) Clin. Exp. Dermatol. , vol.25 , pp. 195-197
    • Owen, C.M.1    Harrison, P.V.2
  • 56
    • 0034124294 scopus 로고    scopus 로고
    • Treatment of severe psoriasis with anti-CD25 monoclonal antibody
    • Mrowietz U, Zhu K, Christophen E. Treatment of severe psoriasis with anti-CD25 monoclonal antibody. Arch Dermatol 2000; 136:675-6.
    • (2000) Arch. Dermatol. , vol.136 , pp. 675-676
    • Mrowietz, U.1    Zhu, K.2    Christophen, E.3
  • 57
    • 0034799416 scopus 로고    scopus 로고
    • Efficacy of Basiliximab, a chimeric anti-IL-2 receptor monoclonal antibody in a patient with severe chronic atopic dermatitis
    • Kagi MK, Heyer G. Efficacy of Basiliximab, a chimeric anti-IL-2 receptor monoclonal antibody in a patient with severe chronic atopic dermatitis. Br J Dermatol 2001; 145:350-1.
    • (2001) Br. J. Dermatol. , vol.145 , pp. 350-351
    • Kagi, M.K.1    Heyer, G.2
  • 58
    • 0034997327 scopus 로고    scopus 로고
    • Prophylactic and therapeutic effects of Daclizumab on collagen induced arthritis in rhesus monkeys
    • Brok HP, Tekoppele JM, Hakimi J, Kerwin JA, Nijenhuis EM. Prophylactic and therapeutic effects of Daclizumab on collagen induced arthritis in rhesus monkeys. Clin Exp Immunol 2001; 124:134-41.
    • (2001) Clin. Exp. Immunol. , vol.124 , pp. 134-141
    • Brok, H.P.1    Tekoppele, J.M.2    Hakimi, J.3    Kerwin, J.A.4    Nijenhuis, E.M.5
  • 60
    • 17944381123 scopus 로고    scopus 로고
    • A multicenter dose escalation trial with denileukin diftitox in patients with severe psoriasis
    • Martin A, Gutierrez E, Muglia J, McDonald CJ, Guzzo C, et al. A multicenter dose escalation trial with denileukin diftitox in patients with severe psoriasis. Am Acad Dermatol 2001; 45:871-81.
    • (2001) Am. Acad. Dermatol. , vol.45 , pp. 871-881
    • Martin, A.1    Gutierrez, E.2    Muglia, J.3    McDonald, C.J.4    Guzzo, C.5
  • 61
    • 0032085463 scopus 로고    scopus 로고
    • Administration of DAB389IL-2 to patients with recalcitrant psoriasis: A double blind phase II multicenter trial
    • Bagel J, Garland WT, Breneman D, Holick M, Littlejohn TW, et al. Administration of DAB389IL-2 to patients with recalcitrant psoriasis: a double blind phase II multicenter trial. J Am Acad Dermatol 1998; 38:938-44.
    • (1998) J. Am. Acad. Dermatol. , vol.38 , pp. 938-944
    • Bagel, J.1    Garland, W.T.2    Breneman, D.3    Holick, M.4    Littlejohn, T.W.5
  • 62
    • 0028353163 scopus 로고
    • The impact of an acute rejection episode on long term renal allograft survival
    • Matas AJ, Gillingham KJ, Payne WD, Najanan JS. The impact of an acute rejection episode on long term renal allograft survival. Transplantation 1994; 57:857-9.
    • (1994) Transplantation , vol.57 , pp. 857-859
    • Matas, A.J.1    Gillingham, K.J.2    Payne, W.D.3    Najanan, J.S.4
  • 63
    • 0023137027 scopus 로고
    • Prolongation of murine cardiac allograft survival by the anti-IL-2 receptor monoclonal antibody AMT-13
    • Kirkman RL, Barrett LV, Koltun WA, Diamantstein T. Prolongation of murine cardiac allograft survival by the anti-IL-2 receptor monoclonal antibody AMT-13. Transplant Proc 1987; 19:618-19.
    • (1987) Transplant Proc. , vol.19 , pp. 618-619
    • Kirkman, R.L.1    Barrett, L.V.2    Koltun, W.A.3    Diamantstein, T.4
  • 65
    • 0024599722 scopus 로고
    • Prolongation of primate renal allograft survival by anti-Tac, an anti-human IL-2 receptor monoclonal antibody
    • Reed MH, Shapiro ME, Strom TB, Milford EL, Carpenter CB, et al. Prolongation of primate renal allograft survival by anti-Tac, an anti-human IL-2 receptor monoclonal antibody. Transplantation 1989; 47:55-9.
    • (1989) Transplantation , vol.47 , pp. 55-59
    • Reed, M.H.1    Shapiro, M.E.2    Strom, T.B.3    Milford, E.L.4    Carpenter, C.B.5
  • 66
    • 0031014538 scopus 로고    scopus 로고
    • A phase I trial of humanized anti-IL-2 receptor antibody in renal transplantation
    • Vincenti F, Lantz M, Bimbaum J, Garovoy M, Mould D. A phase I trial of humanized anti-IL-2 receptor antibody in renal transplantation. Transplantation 1997; 63:33-8.
    • (1997) Transplantation , vol.63 , pp. 33-38
    • Vincenti, F.1    Lantz, M.2    Bimbaum, J.3    Garovoy, M.4    Mould, D.5
  • 67
    • 6844236357 scopus 로고    scopus 로고
    • IL-2 receptor blockade with Daclizumab to prevent acute rejection in renal transplantation
    • Vincenti F, Kirkman R, Light S, Bumgardner G, Pescovitz M, et al. IL-2 receptor blockade with Daclizumab to prevent acute rejection in renal transplantation. N Engl J Med 1998; 338:161-5.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 161-165
    • Vincenti, F.1    Kirkman, R.2    Light, S.3    Bumgardner, G.4    Pescovitz, M.5
  • 69
    • 0031586439 scopus 로고    scopus 로고
    • Randomized trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients
    • Nashan B, Moore R, Amlot P, Schmidt AG, Abeywickrama K. randomized trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients. Lancet 1997; 350:1193-8.
    • (1997) Lancet , vol.350 , pp. 1193-1198
    • Nashan, B.1    Moore, R.2    Amlot, P.3    Schmidt, A.G.4    Abeywickrama, K.5
  • 70
    • 0035884619 scopus 로고    scopus 로고
    • Results of 3 year phase III clinical trials with Daclizumab prophylaxis for prevention of acute rejection after renal transplantation
    • Bumgardner GL, Hardie I, Johnson RW, Lin A, Nashan B, et al. results of 3 year phase III clinical trials with Daclizumab prophylaxis for prevention of acute rejection after renal transplantation. Transplantation 2001; 72:839-45.
    • (2001) Transplantation , vol.72 , pp. 839-845
    • Bumgardner, G.L.1    Hardie, I.2    Johnson, R.W.3    Lin, A.4    Nashan, B.5
  • 71
    • 0035959337 scopus 로고    scopus 로고
    • Daclizumab prophylaxis for prevention of acute rejection in renal transplant recipients with delayed graft function
    • Bumgardner GL, Ramos E, Lin A, Vincenti F. Daclizumab prophylaxis for prevention of acute rejection in renal transplant recipients with delayed graft function. Transplantation 2001; 72:642-7.
    • (2001) Transplantation , vol.72 , pp. 642-647
    • Bumgardner, G.L.1    Ramos, E.2    Lin, A.3    Vincenti, F.4
  • 72
    • 0034898879 scopus 로고    scopus 로고
    • Induction immunosuppression with interleukin-2 receptor antibodies in renal transplant recipients
    • Nair MP, Nampoory MR, Johny KV, Costandi JN, Abdulhalim M, et al. Induction immunosuppression with interleukin-2 receptor antibodies in renal transplant recipients. Transplant Proc 2001; 33:2767-9.
    • (2001) Transplant Proc. , vol.33 , pp. 2767-2769
    • Nair, M.P.1    Nampoory, M.R.2    Johny, K.V.3    Costandi, J.N.4    Abdulhalim, M.5
  • 73
    • 0034594886 scopus 로고    scopus 로고
    • Prevention of rejection in cardiac transplantation by blockade of the IL-2 receptor with a monoclonal antibody
    • Beniaminovitz A, Itescu S, Lietz K, Donovan M, Burke EM, et al. Prevention of rejection in cardiac transplantation by blockade of the IL-2 receptor with a monoclonal antibody. NEJM 2000; 342:613-19.
    • (2000) NEJM , vol.342 , pp. 613-619
    • Beniaminovitz, A.1    Itescu, S.2    Lietz, K.3    Donovan, M.4    Burke, E.M.5
  • 74
    • 0033835561 scopus 로고    scopus 로고
    • The efficacy of Daclizumab for intestinal transplantation: Preliminary report
    • Abu-Elmagd K, Fung J, McGhee W, Martin D, Mazariegos G, et al. The efficacy of Daclizumab for intestinal transplantation: preliminary report. Transplant Proc 2000; 32:1195-6.
    • (2000) Transplant Proc. , vol.32 , pp. 1195-1196
    • Abu-Elmagd, K.1    Fung, J.2    McGhee, W.3    Martin, D.4    Mazariegos, G.5
  • 75
    • 0035086687 scopus 로고    scopus 로고
    • Induction therapy with daclizumab as part of the immunosuppressive regimen in human small bowel and multiorgan transplants
    • Carreno MR, Kato D, Weppler JM, Mathew JM, Fuller L, et al. Induction therapy with daclizumab as part of the immunosuppressive regimen in human small bowel and multiorgan transplants. Transplant Proc 2001; 33:1015-17.
    • (2001) Transplant Proc. , vol.33 , pp. 1015-1017
    • Carreno, M.R.1    Kato, D.2    Weppler, J.M.3    Mathew, J.M.4    Fuller, L.5
  • 76
    • 0036192366 scopus 로고    scopus 로고
    • Improved treatment response with basiliximab immunoprophylaxis after liver transplantation: Results from a double-blind randomised placebo-controlled trial
    • Neuhaus P, Kittur D, Salizzoni M, Nashan B, Clarien PA, et al. Improved treatment response with basiliximab immunoprophylaxis after liver transplantation: results from a double-blind randomised placebo-controlled trial. Liver Transplant 2002; 8:132-42.
    • (2002) Liver Transplant , vol.8 , pp. 132-142
    • Neuhaus, P.1    Kittur, D.2    Salizzoni, M.3    Nashan, B.4    Clarien, P.A.5
  • 77
    • 0033915994 scopus 로고    scopus 로고
    • A single centers clinical experience with quadruple immunosuppression including ATG or IL2 antibodies and mycophenolate mofetil in simultaneous pancreas-kidney transplants
    • Hesse UJ, Troisi R, Jacobs B, Van Vlem B, de Hemptinne B, et al. A single centers clinical experience with quadruple immunosuppression including ATG or IL2 antibodies and mycophenolate mofetil in simultaneous pancreas-kidney transplants. Clin Transplant 2000; 14:340-4.
    • (2000) Clin. Transplant , vol.14 , pp. 340-344
    • Hesse, U.J.1    Troisi, R.2    Jacobs, B.3    Van Vlem, B.4    de Hemptinne, B.5
  • 78
    • 0035667590 scopus 로고    scopus 로고
    • Basiliximab versus antithymocyte globulin for prevention of acute renal allograft rejection
    • Sollinger H, Kaplan B, Pescovitz, Philosophe B, Roza A, et al. Basiliximab versus antithymocyte globulin for prevention of acute renal allograft rejection. Transplantation 2001; 72:1915-19.
    • (2001) Transplantation , vol.72 , pp. 1915-1919
    • Sollinger, H.1    Kaplan, B.2    Pescovitz, A.3    Philosophe, B.4    Roza, A.5
  • 79
    • 0035679065 scopus 로고    scopus 로고
    • The IL2 pathway in clinical immunosuppression
    • Nashan B. The IL2 pathway in clinical immunosuppression. Transplant Proc 2001; 33:3072-4.
    • (2001) Transplant Proc. , vol.33 , pp. 3072-3074
    • Nashan, B.1
  • 81
    • 0028915454 scopus 로고
    • Regulation of lymphocyte survival by the bcl-2 gene family
    • Cory S. Regulation of lymphocyte survival by the bcl-2 gene family. Annu Rev Immunol 1995; 13:513-43.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 513-543
    • Cory, S.1
  • 82
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha chains: Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha chains: breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995; 155:1151-64.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 83
    • 0034597508 scopus 로고    scopus 로고
    • Primary immunodeficiency diseases due to defects in lymphocytes
    • Buckley RH. Primary immunodeficiency diseases due to defects in lymphocytes. N Engl J Med 2000; 343:1313-24.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1313-1324
    • Buckley, R.H.1
  • 84
    • 0033803343 scopus 로고    scopus 로고
    • XSCID: From molecular cause to gene therapy within seven years
    • Leonard WJ. XSCID: from molecular cause to gene therapy within seven years. Mol Med Today 2000; 6:403-7.
    • (2000) Mol. Med. Today , vol.6 , pp. 403-407
    • Leonard, W.J.1
  • 85
    • 0029924265 scopus 로고    scopus 로고
    • The molecular basis of XSCID: Defective cytokine receptor signalling
    • Leonard WJ. The molecular basis of XSCID: defective cytokine receptor signalling. Annu Rev Med 1996; 47:229-39.
    • (1996) Annu. Rev. Med. , vol.47 , pp. 229-239
    • Leonard, W.J.1
  • 86
    • 0029164841 scopus 로고
    • Mutations of Jak3 gene in patients with severe autosomal severe combined immune deficiency
    • Macchi P, Villa A, Gillani S, Sacco MG, Frattini A, et al. Mutations of Jak3 gene in patients with severe autosomal severe combined immune deficiency. Nature 1995; 377:65-8.
    • (1995) Nature , vol.377 , pp. 65-68
    • Macchi, P.1    Villa, A.2    Gillani, S.3    Sacco, M.G.4    Frattini, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.