The copper/zinc ratio in patients with hepatocellular carcinoma

Journal of Gastroenterology

Volumn 38, Issue 1, 2003, Pages 104-105

  Ebara, Masaaki ^a   Fukuda, Hiroyuki ^a   Saisho, Hiromitsu ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; COPPER; METALLOTHIONEIN; ZINC;

CANCER GROWTH; COPPER BLOOD LEVEL; DIFFUSION WEIGHTED IMAGING; EDITORIAL; GASTROINTESTINAL TUMOR; HISTOPATHOLOGY; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER PARENCHYMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT CODING; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TUMOR VOLUME; ZINC BLOOD LEVEL;

CARCINOMA, HEPATOCELLULAR; COPPER; HUMANS; LIVER NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; ZINC;

EID: 0037288977     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350300016     Document Type: Editorial

References (8)

1. Poo JL, Rosas-Romero R, Montemayor AC, Isoard F, Uribe M. Diagnostic value of the copper/zinc ratio in hepatocellular carcinoma: a case control study. J Gastroenterol 2003;38:45-51.
2. Poo JL, Rosas-Romero R, Rodriguez F, Silencio JL, Munoz R, Bourges H, et al. Serum zinc concentrations in two cohorts of 153 healthy subjects and 100 cirrhotic patients from Mexico City. Dig Dis 1995;13:136-42.
3. Shang YJ, Zhao DH, Huang CX. Changes in serum copper levels and its clinical significance in patients with cirrhosis and hepatocellular carcinoma. Chin J Intern Med 1994;33:113-6.
4. Hatano R, Ebara M, Fukuda H, Yoshikawa M, Sugiura N, Kondo F, et al. Accumulation of copper in the liver and hepatic injury in chronic hepatitis C. J Gastroenterol Hepatol 2000;1:786-91.
5. Ebara M, Fukuda H, Hatano R, Saisho H, Nagato Y, Suzuki K, et al. Relationship between copper, zinc and metallothionein in hepatocellular carcinoma and its surrounding liver parenchyma. J Hepatol 2000;33:415-22.
6. Ebara M, Fukuda H, Kojima Y, Morimoto N, Yoshikawa M, Sugiura N, et al. Small hepatocellular carcinoma: relationship of signal intensity to histologic findings and metal content of the tumor and surrounding hepatic parenchyma. Radiology 1999;210: 81-8.
7. Tashiro-Itoh T, Ichida T, Matsuda Y, Satoh T, Sugiyama M, Tanaka Y, et al. Metallothionein expression and concentrations of copper and zinc are associated with tumor differentiation in hepatocellular carcinoma. Liver 1997;17:300-6.
8. Sakurai H, Satoh H, Hatanaka A, Sawada T, Kawano K, Hagino T, et al. Unusual generation of hydroxyl radicals in hepatic copper-metallothionein of LEC (Long Evans Cinnamon) rats in the presence of hydrogen peroxide. Biochem Biophys Res Commun 1994;199:313-8.