The induction of heme oxygenase-1 by exogenous nitric oxide in ex vivo normal human skin

Journal of Dermatology

Volumn 30, Issue 1, 2003, Pages 17-25

  Shimizu, Kazuhiro ^a   Naito, Shinji ^b   Urata, Yoshishige ^a   Takamiyagi, Atsushi ^c   Bae, Sang Jae ^a   Ogawa, Fumihide ^a   Kondo, Takahito ^a   Katayama, Ichiro ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Ureshino Medical Center   (Japan)

^c NONE

Author keywords

Ex vivo; Heme oxygenase 1; Human skin; Nitric oxide

Indexed keywords

BILIRUBIN; BILIVERDIN; CARBON MONOXIDE; HEME; HEME OXYGENASE 1; MESSENGER RNA; NEUROTRANSMITTER; NITRIC OXIDE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; ENZYME INDUCTION; EXPLANT; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN; VASODILATATION;

ADULT; AGED; AGED, 80 AND OVER; CULTURE TECHNIQUES; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NITRIC OXIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN;

EID: 0037286706     PISSN: 03852407     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. O'Dell TJ, Hawkins RP, Kandel ER, Aracio Q: Tests of the roles of two diffusible substances in long-term potentiation: Evidence for nitric oxide as a possible early retrograde messenger, Proc Natl Acad Sci USA, 88: 11285-11289, 1991.
2. Schuman EM, Madison DV: A requirement for the intercellular messenger nitric oxide in long-term potentiation, Science, 254: 1503-1506, 1991.
3. Verma A, Hirsch DJ, Glatt CE, Ronnett GV, Snyder SH: Carbon monoxide: A putative neural messenger, Science, 259: 381-384, 1993.
4. Suematsu M, Kashiwagi S, Sano T, Goda N, Shinoda Y, Ishimura Y: Carbon monoxide as an endogenous modulator of hepatic vascular perfusion, Biochem Biophys Res Commun, 205: 1333-1337, 1994.
5. Keyse SM, Tyrrell RM: Heme oxygenase is the major 32-kDa stress protein in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenate, Proc Natl Acad Sci USA, 86: 99-103, 1989.
6. Soriani M, Rice-Evans C, Tyrrell RM: Modulation of the UVA activation of heme oxygenase, collagenease and cyclooxygenase gene expression by epigallocatechin in human skin cells, FEBS Letter, 439: 253-257, 1998.
7. Applegate LA, Luscher P, Tyrrell R: Induction of heme oxygenase: A general response to oxidant stress in cultured mammalian cells, Cancer Res, 51: 974-978, 1991.
8. Clark JE, Green CJ, Motterlini R: Involvement of the heme oxygenase-carbon monoxide pathway in keratinocyte proliferation, Biochem Biophys Res Commun, 241: 215-220, 1997.
9. Yee EL, Pitt BR, Billiar TR, Kim Y-M: Effect of nitric oxide on heme metabolism in pulmonary artery endothelial cells. Am J Physiol, 271: L512-L518, 1996.
10. Foresti R, Motterlini R: The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis, Free Radic Res, 31: 459-475, 1999.
11. Bruch-Gerharz D, Fehsel K, Suschek C, Michel G, Ruzicka T, Kolb-Bachofen V: A proinflammatory activity of intrleukin 8 in human skin: Expression of the inducible nitric oxide synthase in psoriatic lesions and cultured keratinocytes, J Exp Med, 184: 2007-2012, 1996.
12. Shimizu K, Naito S, Urata Y, Sekine I, Kondo T, Katayama I: Inducible nitric oxide synthase is expressed in granuloma pyogenicum, Br J Dermatol, 138: 769-773, 1998.
13. Reeve VE, Tyrrell RM: Heme oxygenase induction mediates the photoimmunoprotective activity of UVA radiation in the mouse, Proc Natl Acad Sci USA, 96: 9317-9321, 1999.
14. Lee T-S, Chau L-Y: Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nature Med, 8: 240-246, 2002.
15. Ormerod AD, Copeland P, Hay I, Husain A, Ewen SW: The inflammatory and cytotoxic effects of a nitric oxide releasing cream on normal skin, J Invest Dermatol, 113: 392-397, 1999.
16. Acevedo CH, Ahmed A: Hemeoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy, J Clin Invest, 101: 949-955, 1998.
17. Horikoshi T, Danenberg KD, Stadlbauer THW, et al: Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diqohorase gene expression in human tumors using the polymerase chain reaction, Cancer Res, 52: 108-116, 1992.
18. Nakayama T, Ito M, Otsuru A, Naito S, Nakashima M and Sekine I: Expression of the ets-1 proto-oncogene in human thyroid tumor, Mod Pathol, 12: 61-68, 1999.
19. Lavrovsky Y, Schwartzman ML, Levere RD, Kappas A, Abraham NG: Identification of NFkB and AP-2 binding sites in the promoter region of the region of the human heme oxygenase-1 gene, Proc Natl Acad Sci USA, 91: 5987-5991, 1994.
20. Deramaudt BMJM, Remy P, Abraham NG: Upregulation of human heme oxygenase gene expression by Ets-family proteins, J Cell Biochem, 72: 311-321, 1999.
21. Hara E, Takahashi K, Takeda K, et al: Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors, Biochem Pharmacol, 58: 227-236, 1999.
22. Demple B: Genetic responses against nitric oxide toxicity, Braz J Med Biol Res, 32: 1417-1427, 1999.
23. Kondo S, Hozumi Y: Organ culture of skin of rabbits and guinea pigs: Maintenance of complete keratinization and effect of lithium on keratinization, J Dermatol, 13: 92-100, 1986.
24. Durante W, Kroll MH, Christodoulides N, Peyton KJ, Schafer AI: Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells, Cir Res, 80: 557-564, 1997.
25. Abraham NG: Quantitation of heme oxygenase (HO-1) copies in human tissues by competitive RT/PCR, in Armstrong D (ed): Free Radical and Antioxidant Protocols, Totowa, Humana Press, 1998, pp 199-209.
26. Rottman JB, Tompkins WA, Tompkins MB: A reverse transcription-quantitative competitive polymerase chain reaction (RT-qcPCR) technique to measure cytokine gene expression in domestic mammals, Vet Pathol, 33: 242-248, 1996.
27. Hayward-Lester A, Oefner PJ, Doris PA: Rapid quantification of gene expression by competitive RT-PCR and ion-pair reversed-phase HPLC, Biotechniques, 20: 250-257, 1996.