Physiological, subjective and performance effects of pseudoephedrine and phenylpropanolamine during endurance running exercise

International Journal of Sports Medicine

Volumn 24, Issue 1, 2003, Pages 3-8

  Chester, N ^a   Reilly, T ^a   Mottram, D R ^a  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

Drugs; Sports performance; Sympathomimetic amines

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; DECONGESTIVE AGENT; NON PRESCRIPTION DRUG; PHENYLPROPANOLAMINE; PSEUDOEPHEDRINE;

ADULT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DYNAMIC EXERCISE; EXERCISE TEST; FATTY ACID BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HEART RATE; HUMAN; HUMAN EXPERIMENT; LACTATE BLOOD LEVEL; LUNG GAS EXCHANGE; LUNG MINUTE VOLUME; MALE; NORMAL HUMAN; OXYGEN CONSUMPTION; PHYSICAL STRESS; RUNNING; STATISTICAL ANALYSIS; TREADMILL EXERCISE;

ADULT; BLOOD GLUCOSE; DOUBLE-BLIND METHOD; EPHEDRINE; EXERCISE; EXERTION; FATTY ACIDS, NONESTERIFIED; HEART RATE; HUMANS; LACTIC ACID; MALE; PHENYLPROPANOLAMINE; PHYSICAL ENDURANCE; PLACEBO EFFECT; RUNNING; SYMPATHOMIMETICS; TASK PERFORMANCE AND ANALYSIS; TIME;

EID: 0037284905     PISSN: 01724622     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-37193     Document Type: Article

References (23)

1. Berstein E, Diskant BM. Phenylpropanolamine: A potentially hazardous drug. Ann Emerg Med 1982; 11: 311-315
2. Borg GV. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982; 14: 377-387
3. Bright TP, Sandage BW, Fletcher HP. Selected cardiac and metabolic responses to pseudoephedrine with exercise. J Clin Pharmacol 1981; 21: 488-492
4. British Association of Sport and Exercise Sciences. Position statement on the physiological assessment of the elite competitor. 1997
5. Bye C, Dewsbury D, Peck AW. Effects on the human central nervous system of two isomers of ephedrine and triprolidine and their interaction. Br J Clin Pharmac 1974; 1: 71-78
6. Chester NJ. The use of exogenous sympathomimetic amines in sport and exercise. PhD Thesis. Liverpool: John Moores University, 2000
7. Clemons JM, Crosby SL. Cardiopulmonary and subjective effects of a 60 mg dose of pseudoephedrine on graded treadmill exercise. J Sports Med Phys Fit 1993; 33: 405-412
8. Cohen J. Statistical power analysis for the behavioural sciences. 2nd ed. New Jersey: Lawrence Erlbaum, 1988
9. de Meersman R, Getty D, Schaefer DC. Sympathomimetics and exercise enhancement: all in the mind? Pharmacol Biochem Behav 1987; 28: 361-365
10. Doyle JA, Martinez AL. Reliability of a protocol for testing endurance performance in runners and cyclists. Res Quart Exerc Sport 1998; 69: 304-307
11. Gibson GJ, Warrell DA. Hypertensive crisis and phenylpropanolamine. Lancet 1972; 2: 492
12. Gillies H, Derman WE, Noakes TD, Smith P, Evans A, Gabriels G. Pseudoephedrine is without ergogenic effects during prolonged exercise. J Appl Physiol 1996; 81: 2611-2617
13. Hickey MS, Costill DL, McConell GK, Widrick JJ, Tanaka H. Day to day variation in time trial cycling performance. Int J Sports Med 1992; 13: 467-470
14. Johnson DA, Etter HS, Reeves DM. Stroke and phenylpropanolamine use. Lancet 1983; ii: 970
15. Meeuwisse WH, McKenzie DC, Hopkins SR, Road JD. The effect of salbutamol on performance in elite nonasthmatic athletes. Med Sci Sports Exerc 1992; 24: 1161-1166
16. Norvenius G, Widerlov E, Lönnerhölm G. Phenylpropanolamine and mental disturbance. Lancet 1979; 2: 1367-1368
17. Palmer GS, Dennis SC, Noakes TD, Hawley JA. Assessment of the reproducibility of performance testing on an air-braked cycle ergometer. Int J Sports Med 1996; 17: 293-298
18. Schabort EJ, Hawley JA, Hopkins WG, Mujika I, Noakes TD. A new reliable laboratory test of endurance performance of road cyclists. Med Sci Sports Exerc 1998; 30: 1744-1750
19. Schabort EJ, Hopkins WG, Hawley JA. Reproducibility of self-paced treadmill performance of trained endurance runners. Int J Sports Med 1998; 19: 48-51
20. Schwenk TL. Psychoactive drugs and athletic performance. Physician Sportsmed 1997; 25: 32-46
21. Sidney KH, Lefcoe NM. The effects of ephedrine on the physiological and psychological responses to submaximal and maximal exercise in man. Med Sci Sports 1977; 9: 95-99
22. Swain RA, Harsha DM, Baenziger J, Saywell RM. Do pseudoephedrine or phenylpropanolamine improve maximum oxygen uptake and time to exhaustion? Clin J Sport Med 1997; 7: 168-173
23. Wadler GI, Hainline B. Drugs and the Athlete. Philadelphia: F.A. Davis Company, 1989