High prevalence of the -α3.7 deletion among thalassemia patients in Iran

Hemoglobin

Volumn 27, Issue 1, 2003, Pages 53-55

  Neishabury, Maryam ^a   Oberkanins, Christian ^b   Moheb, Lia Abbasi ^a   Pourfathollah, Ali Akbar ^c   Kahrizi, Kimia ^a   Keyhany, Elahe ^a   Krugluger, Walter ^d   Najmabadi, Hossein ^a  

^a UNIVERSITY OF SOCIAL WELFARE AND REHABILITATION SCIENCES   (Iran)

^b VIENNALAB DIAGNOSTICS GMBH   (Austria)

^c TARBIAT MODARES UNIVERSITY   (Iran)

^d KRANKENANSTALT RUDOLFSTIFTUNG   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; BETA GLOBIN; FERRITIN; HEMOGLOBIN; HEMOGLOBIN A2; IRON; GLOBIN;

AGAR GEL ELECTROPHORESIS; ALPHA THALASSEMIA; ARTICLE; CHROMOSOME; CONTROLLED STUDY; ETHNIC GROUP; FERRITIN BLOOD LEVEL; GENE AMPLIFICATION; GENE DELETION; GENOTYPE; GLOBIN GENE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; IRAN; IRON BINDING CAPACITY; IRON BLOOD LEVEL; IRON DEFICIENCY ANEMIA; MAJOR CLINICAL STUDY; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MICROCYTIC ANEMIA; POLYMERASE CHAIN REACTION; PREVALENCE; RANDOMIZATION; ALLELE; GENETICS;

ALLELES; ALPHA-THALASSEMIA; ANEMIA, HYPOCHROMIC; ETHNIC GROUPS; GLOBINS; HUMANS; IRAN; PREVALENCE; SEQUENCE DELETION;

EID: 0037281209     PISSN: 03630269     EISSN: None     Source Type: Journal    
DOI: 10.1081/HEM-120018438     Document Type: Article

References (8)

1. Higgs DR, Vickers MA, Wilkie AOM, Pretorius I-M, Jarman AP, Weatherall DJ. A review of the molecular genetics of the human α-globin gene cluster. Blood 1989; 73:1081-1104.
2. Old J. Haemoglobinopathies. Prenat Diagn 1996; 16:1181-1186.
3. Baysal E, Huisman THJ. Detection of common deletional α-thalassemia-2 determinants by PCR. Am J Hematol 1994; 46:208-213.
4. El-Kalla S, Baysal E. α-Thalassemia in the United Arab Emirates. Acta Haematol 1998; 100:49-53.
5. Diejomaoh FM, Haider MZ, Dalal H, Abdulaziz A, D'Souza TM, Adekile AD. Influence of α-thalassemia trait on the prevalence and severity of anemia in pregnancy among women in Kuwait. Acta Haematol 2000;104:92-94.
6. Kan YW, Nathan DG. Mild thalassemia: the result of interactions of α and β thalassemia genes. J Clin Invest 1970; 49:635-642.
7. 0-thalassemia in combination with a homozygosity for the α-thalassemia 3.7 kb deletion. Hemoglobin 2000; 24(3):259-263.
8. Najmabadi H, Karimi-Nejad R, Sahebjam S, Pourfarzad F, Teimourian S, Sahebjam F, Amirizadeh N, Karimi-Nejad MH. The β-thalassemia mutation spectrum in the Iranian population. Hemoglobin 2001; 25(3):285-296.