A novel vitamin E derivative (TMG) protects against gastric mucosal damage induced by ischemia and reperfusion in rats

Digestive Diseases and Sciences

Volumn 48, Issue 1, 2003, Pages 54-58

  Ichikawa, Hiroshi ^a   Yoshida, Norimasa ^a   Takano, Hiroshisa ^a   Ishikawa, Takeshi ^a   Handa, Osamu ^a   Takagi, Tomohisa ^a   Naito, Yuji ^a   Murase, Hironobu ^b   Yoshikawa, Toshikazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b CCI Corporation   (Japan)

Author keywords

Cytokine; Free radical; Ischemia reperfusion; Neutrophil; Vitamin E

Indexed keywords

2 (ALPHA DEXTRO GLUCOPYRANOSYL)METHYL 2,5,7,8 TETRAMETHYLCHROMAN 6 OL; ALPHA TOCOPHEROL DERIVATIVE; ANTIOXIDANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 2BETA; FREE RADICAL; MYELOPEROXIDASE; THIOBARBITURIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELIAC ARTERY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; INFLAMMATION; ISCHEMIA; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; STOMACH MUCOSA; STOMACH MUCOSA LESION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIOXIDANTS; CHROMANS; GASTRIC MUCOSA; GLYCOSIDES; LIPID PEROXIDATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 0037280598     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021778229997     Document Type: Article

References (20)

1. Granger DN, Rutili G, McCord JM: Superoxide radicals in feline intestinal ischemia. Gastroenterology 81:22-29, 1981
2. Yoshikawa T, Ueda S, Naito Y, Takahashi S, Oyamada H, Morita Y, Yoneta T, Kondo M: Role of oxygen-derived free radical in gastric mucosal injury induced by ischemia or ischemia-reperfusion in rats. Free Radic Res Commun 7:285-291, 1989
3. Burton GW, Ingold KU: Vitamin E: Application of the principles of physical organic chemistry to the exploration of its structure and function. Accounts of Chem Res 19:194-201, 1986
4. Niki B: Antioxidants in relation to lipid peroxidation. Chem Phys Lipids 44:227-232, 1987
5. Burton GW, Traber MG: Vitamin E: Antioxidant activity, biokinetics, and bioavailability. Annu Rev Nutr 10:357-382, 1990
6. Burton GW, Joyce A: Is vitaminte E the only lipid-soluble chain-breaking antioxidant in human blood plasma and erythrocy membrane? Arch Biochem Biophys 221:281-290, 1983.
7. Grams GW: Oxidation of α-tocopherol by singlet oxygen. Tetrahedron Lett 50:823-825, 1971
8. Nishikimi M, Yamada H, Yagi K: Oxidation by superoxide of tocopherols dispersed in aqueous media with deoxycholate. Biochim Biophys Acta 627:101-108, 1980
9. Fukuzawa K, Gebicki JM: Oxidation of α-tocopherol in micelles and liposomes by the hydroxy, perhydroxy and superoxide free radicals. Arch Biochem Biophys 226:242-251, 1983
10. Ohkawa H, Ohnishi N, Yagi K: Assay for lipid peroxides for animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358, 1979
11. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275, 1951
12. Krawisz JE, Sharon P, Stenson WF: Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenterology 87:1344-1350, 1984
13. Yoshikawa T, Ueda S, Takahashi S, Naito Y, Oyamada H, Morita Y, Tanigawa T, Takemura T, Sugino S, Kondo M: [Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats]. Nippon Shokakibyo Gakkai Zasshi 87:8-15, 1990
14. Yoshikawa T, Yasuda M, Ueda S, Naito Y, Tanigawa T, Oyamada H, Kondo M: Vitamin E in gastric mucosal injury induced by ischemia-reperfusion. Am J Clin Nutr 53:210S-214S, 1991
15. Naito Y, Yoshikawa T, Matsuyama K, Yagi N, Arai M, Nakamura Y, Kaneko T, Yoshida N, Kondo M: Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats. Free Radic Biol Med 24:494-502, 1998
16. Naito Y, Yoshikawa T, Matsuyama K, Yagi N, Kasai K, Sugimoto N, Masui Y, Yoshida N, Kondo M: Effect of vitamin E in gastric mucosal injury induced by ischaemia-reperfusion in nitric oxide-depleted rats. Aliment Pharmacol Ther 13:553-559, 1999
17. Ichikawa H, Flores S, Kvietys PR, Wolf RE, Yoshikawa T, Granger DN, AW TY: Molecular mechanisms of anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells. Circ Res 81:922-931, 1997
18. Murase H, Yamauchi R, Kato K, Kunieda T, Terao J: Synthesis of a novel vitamin E derivative, 2-(alpha-D-glucopyranosyl) methyl-2,5,7,8-tetramethylchroman-6-ol, by alpha-glucosidase-catalyzed transglycosylation. Lipids 32:73-78, 1997
19. Yoshida N, Yoshikawa T, Yamaguchi T, Naito Y, Tanigawa T, Murase H, Kondo M: A novel water-soluble vitamin E derivative protects against experimental colitis in rats. Antioxid Redox Signal 1:555-562, 1999
20. Murase H, Moon J, Yamauchi R, Kato K, Kunieda T, Yoshikawa T, Terao J: Antioxidant activity of a novel vitamin E derivative, 2-(αD-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol. Free Radic Biol Med 24:217-225, 1998