Stomal recurrence: Pathophysiology, treatment and prevention

Acta Oto-Laryngologica

Volumn 123, Issue 3, 2003, Pages 421-432

  Kowalski, Luiz P ^a   Rinaldo, Alessandra ^b   Robbins, K Thomas ^g   Pellitteri, Phillip K ^c   Shaha, Ashok R ^d   Weber, Randal S ^e   Ferlito, Alfio ^b,f  

^a A C CAMARGO CANCER CENTER   (Brazil)

^b UNIVERSITY OF UDINE   (Italy)

^c GEISINGER MEDICAL CENTER   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f UNIVERSITY HOSPITAL OF UDINE   (Italy)

^g NONE

Author keywords

[No Author keywords available]

Indexed keywords

CANCER PREVENTION; DISEASE CLASSIFICATION; HUMAN; METASTASIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SURGICAL APPROACH; TRACHEA TUMOR; TUMOR RECURRENCE;

EID: 0037279199     PISSN: 00016489     EISSN: None     Source Type: Journal    
DOI: 10.1080/00016480310000683a     Document Type: Review

References (158)

1. The Department of Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 1991; 324: 1685-90.
2. Lefebvre JL, Chevalier D, Luboinski B, Kirkpatrick A, Collette L, Sahmoud T. Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group. J Natl Cancer Inst 1996; 88: 890-9.
3. Ferlito A, Shaha AR, Lefebvre J-L, Silver CE, Rinaldo A. Organ and voice preservation in advanced laryngeal cancer [Guest Editorial]. Acta Otolaryngol 2002; 122: 438-42.
4. Biller HE Davis WH, Ogura JH. Delayed contralateral cervical metastases with laryngeal and laryngopharyngeal cancers. Laryngoscope 1971; 81: 1499-502.
5. Strong EW. Sites of treatment failure in head and neck cancer. Cancer Treat Symp 1983; 2: 5-20.
6. Kowalski LP. Recidiva de carcinomas da laringe e da parte laríngea da faringe na área do traqueostoma: análise dos fatores de risco e do tratamento [MS thesis], São Paulo, Brazil: Escola Paulista de Medicina, 1986.
7. Weber RS, Marvel J, Smith P, Hankins P, Wolf P, Goepfert H. Paratracheal lymph node dissection for carcinoma of the larynx, hypopharynx, and cervical esophagus. Otolaryngol Head Neck Surg 1993; 108: 11-7.
8. Jackson C, Jackson CL. Cancer of the larynx. Philadelphia, PA: Saunders; 1939.
9. Alonso JM. Cáncer laríngeo. Madrid: Paz Montalvo; 1954.
10. Fruhling L, Spehler H. Contribution a l'étude anatomo-clinique des tumeurs de la trachée: apropos de 5 cas de tumeurs primitives et de 24 cas de tumeurs secondaires de la trachée. Ann Otolaryngol Chir Cervicofac 1951; 68: 543-64.
11. Ogura JH, Bello JA. Laryngectomy and radical neck dissection for carcinoma of the larynx. Laryngoscope 1952; 62: 1-52.
12. Keim WF, Shapiro MJ, Rosin HD. Study of postlaryngectomy stomal recurrence. Arch Otolaryngol 1965; 81: 183-6.
13. Latella PD. An analysis of 240 cases of cancer of the larynx, with respect to the terminal phases and death. Ann Otol 1952; 61: 266-75.
14. Ormerod FC, Shaw HJ. An account of morbidity and mortality associated with total laryngectomy. J Laryngol Otol 1956; 70: 433-52.
15. Mounier-Kuhn P, Gaillard J, Bonnefoy J, Fontvieille J. Les recidives peri-canulaires apres laryngectomie donnees therapeutiques. J Fr Otorhinolaryngol 1959; 8: 519-22.
16. Norris CM. Causes of failure in surgical treatment of malignant tumors of the larynx. Ann Otol 1959; 68: 487-508.
17. Boccuzzi V, Tomasetti L. Sulle recidive reali ed apparenti della stomia tracheale dopo laringectomia totale. Boll Mal Orec Gola Naso 1961; 79: 179-89.
18. Bauer WC, Edwards DL, McGavran MH. A critical analysis of laryngectomy in the treatment of epidermoid carcinoma of larynx. Cancer 1962; 15: 263-70.
19. Debain JJ, Siardet J, Andrieu-Guitrancourt J. Les récidives péritrachéales après laryngectomie totale. Ann Otolaryngol Chir Cervicofac 1965; 82: 382-4.
20. Bolla A, Scolari R. Le recidive peristomali del cancro laringeo. Minerva Otorinolaringol 1967; 17: 157-60.
21. Burnam JA, Hudson WR. Stomal recurrence of malignancy: an evaluation and its significance in post-laryngectomy patients. South Med J 1967; 60: 823-6.
22. Molinari R, Milanesi I. Interpretazione patogenetica delle recidive al tracheostoma in laringectomizzati per carcinoma. Tumori 1967; 53: 299-313.
23. Loewy A, Laker HI. Tracheal stoma problems. Arch Otolaryngol 1968; 87: 477-83.
24. Condon HA. Postlaryngectomy stomal recurrence. The influence of endotracheal anaesthesia. Br J Anaesth 1969; 41: 531-3.
25. de Jong PC. Intubation and tumour implantation in laryngeal carcinoma. Pract Otorhinolaryngol 1969; 31: 119-21.
26. Modlin B, Ogura JH. Post-laryngectomy tracheal stomal recurrences. Laryngoscope 1969; 79: 239-50.
27. Kuehn PG, Tennant R. Surgical treatment of stomal recurrences in cancer of larynx. Am J Surg 1971; 122: 445-50.
28. Stell PM, van den Broek P. Stomal recurrence after laryngectomy: aetiology and management. J Laryngol Otol 1971; 85: 131-40.
29. Bonneau RA, Lehman RH. Stomal recurrence following laryngectomy. Arch Otolaryngol 1975; 101: 408-12.
30. Schneider JJ, Lindberg RD, Jesse RH. Prevention of tracheal stoma recurrences after total laryngectomy by postoperative irradiation. J Surg Oncol 1975; 7: 187-90.
31. Myers EM, Ogura JH. Stomal recurrences: a clinico-pathological analysis and protocol for future management. Laryngoscope 1979; 89:1121-8.
32. Weisman RA, Colman M, Ward PH. Stomal recurrence following laryngectomy. A critical evaluation. Ann Otol 1979; 88: 855-60.
33. Calzavara F, Pizzi GB, Corti L, Zorat PL, Sotti G. Localizzazioni secondarie sul tracheostoma dopo laringectomia e radioterapia nel cancro cella laringe. Atti Riunioni Integrate di Oncologia, Fiera del Levante, Bari, Italy, 1980: 160.
34. Malamov M, Bogdanov E, Edrev E. Sobre el problema de las recidivas alrededor del traqueostoma después de la laringectomia por cáncer laríngeo. Rev Cub Cirug 1980; 19: 125-8.
35. Mantravadi R, Katz AM, Skolnik EM, Becker S, Freehling DJ, Friedman M. Stomal recurrence. A critical analysis of risk factors. Arch Otolaryngol 1981; 107: 735-8.
36. Camprini C, Bartolini A, Farneti G, Macca E. Recidive tracheostomali dopo laringectomia totale. Acta Otorhinolaryngol Ital 1982; 2: 201-12.
37. Bignardi L, Gavioli C, Staffieri A. Tracheostomal recurrences after laryngectomy. Arch Otorhinolaryngol 1983; 238: 107-13.
38. Fini-Storchi O, Rucci L, Fiorentino G. Sull'importanza di una pregressa tracheotomia nelle recidive alla stomia tracheale dopo laringectomia totale. Otorinolaringologia 1983; 33: 9-13.
39. Antonelli A, Oldini C, Leonardelli GB, Ghidoni P. La recidiva postoperatoria stomale/peristomale del cancro laringeo. Studio anatomo-clinico di 18 osservazioni. Otorinolaringologia 1984; 34: 41-6.
40. Cervellera G, Fiorella R, Petrone D. Tracheotomia e recidiva neoplastica peristomale. Acta Otorhinolaryngol Ital 1984; 4: 231-8.
41. DiSantis DJ, Balfe DM, Hayden RE, Sagel SS, Sessions D, Lee JK. The neck after total laryngectomy: CT study. Radiology 1984; 153: 713-7.
42. Komiyama S, Watanabe H, Yanagita T, Kuwano M, Hiroto I. Inhibition of stomal recurrence in laryngectomy with preoperative FAR therapy - a statistical evaluation. Auris Nasus Larynx 1984; 11: 43-9.
43. Yuen A, Medina JE, Goepfert H, Fletcher G. Management of stage T3 and T4 glottic carcinomas. Am J Surg 1984; 148: 467-72.
44. Amatsu M, Makino K, Kinishi M. Stomal recurrence - etiological factors and prevention. Auris Nasus Larynx 1985; 12: 103-10.
45. Spriano G, Piantanida R, Roberto V, Premoli A. Le recidive peritracheostomali dopo laringectomia totale. Acta Otorhinolaryngol Ital 1985; 5: 497-505.
46. Griebie MS, Adams GL. "Emergency" laryngectomy and stomal recurrence. Laryngoscope 1987; 97: 1020-4.
47. Breneman JC, Bradshaw A, Gluckman J, Aron BS. Prevention of stomal recurrence in patients requiring emergency tracheostomy for advanced laryngeal and pharyngeal tumors. Cancer 1988; 62: 802-5.
48. Lahoz T, Faubel M, Campos JJ. Las recidivas periestomales tras, laringuectomía total. An Otorrinolaringol Ibero Am 1989; 26: 649-57.
49. Snow GB, Balm AJM. Il ruolo della chemioterapia nel carcinoma squamoso della laringe. In: Carlon G, Serafini I, eds. Il carcinoma sovraglottic. Padua, Italy: Piccin; 1989. 245-56.
50. Barr GD, Robertson AG, Liu KC. Stomal recurrence: a separate entity? J Surg Oncol 1990; 44: 176-9.
51. Rubin J, Johnson JT, Myers EN. Stomal recurrence after laryngectomy: interrelated risk factor study. Otolaryngol Head Neck Surg 1990; 103: 805-12.
52. Castro A, Ostos P, Mellado R, Cantillo E, López-Villarejo P. Nuestra experiencia en recidiva estomal de laringuectomizados con traqueostomia previa. An Otorrinolaringol 1991; 6: 57-60.
53. McCombe A, Stell PM. Emergency laryngectomy. J Laryngol Otol 1991; 105: 463-5.
54. Rockley TJ, Powell J, Robin PE, Reid AP. Post-laryngectomy stomal recurrence: tumour implantation or paratracheal lymphatic metastasis? Clin Otolaryngol 1991; 16: 43-7.
55. Esteban F, Moreno JA, Delgado-Rodriguez M, Mochon A. Risk factors involved in stomal recurrence following laryngectomy. J Laryngol Otol 1993; 107: 527-31.
56. Hosal IN, Önerci M, Turan E. Peristomal recurrence. Am J Otolaryngol 1993; 14: 206-8.
57. Murakami Y. Stomal recurrence after total laryngectomy. In: Ferlito A, ed. Neoplasms of the larynx. Edinburgh, UK: Churchill Livingstone; 1993. 545-57.
58. Narula AA, Sheppard IJ, West K, Bradley PJ. Is emergency laryngectomy a waste of time? Am J Otolaryngol 1993; 14: 21-3.
59. Kuratomi Y, Tomita K, Inokuchi A, Komiyama S. Stomal recurrence in laryngectomy with preoperative combination therapy of 5-FU, vitamin A, and radiation (FAR therapy). 2nd World Congress on Laryngeal Cancer, Sydney, N.S.W., 1994: Abstract P213.
60. León X, Quer M, Burgués J, Abelló P, Vega M, de Andrés L. Prevention of stomal recurrence. Head Neck 1996; 18: 54-9.
61. Yotakis J, Davris S, Kontozoglou T, Adamopoulos G. Evaluation of risk factors for stomal recurrence after total laryngectomy. Clin Otolaryngol 1996; 21: 135-8.
62. Yuen APW, Wei WI, Ho WK, Hui Y. Risk factors of tracheostomal recurrence after laryngectomy for laryngeal carcinoma. Am J Surg 1996; 172: 263-6.
63. Zbären P, Greiner R, Kengelbacher M. Stoma recurrence after laryngectomy: an analysis of risk factors. Otolaryngol Head Neck Surg 1996; 114: 569-75.
64. Martínez Vidal J, López Amado M, Herranz Gonzáles-Botas J, Vázquez Barro C, García Sarandeses A. [Peritracheal stomal recurrence and emergency tracheotomy]. Acta Otorrinolaringol Esp 1997; 48: 291-4 (in Spanish).
65. Metternich FU, Brusis T Parastomale Tumoren nach Laryngektomie: Ätiologie und Therapie. Laryngorhinootologie 1997; 76: 88-95.
66. el Shennawy M, Fayek A, el Sharkawy L. A study of peristomal recurrence. Rev Laryngol Otol Rhinol (Bord) 2000; 121: 117-20.
67. Martín Villares C, Pérez Carretero M, Ortega Medina L, González Gimeno M J, Iglesias Moreno MC, Poch Broto J. [Stomal relapse after laryngectomy. An inevitable late complication?]. Acta Otorrinolaringol Esp 2000; 51: 501-5 (in Spanish).
68. Reddy SP, Narayana A, Melian E, Kathuria S, Leman C, Emami B. Stomal recurrence in patients with T1 glottic cancer after salvage laryngectomy for radiotherapy failures. Role of p53 overexpression and subglottic extension. Am J Clin Oncol 2001; 24: 124-7.
69. Imauchi Y, Ito K, Takasago E, Nibu K-I, Sugasawa M, Ichimura K. Stomal recurrence after total laryngectomy for squamous cell carcinoma of the larynx. Otolaryngol Head Neck Surg 2002; 126: 63-6.
70. Santoro R, Franchi A, Tempesti C, Sardi I, Polli G. Stomal recurrence following total laryngectomy: clinical and molecular analysis of a series. Submitted.
71. Ferlito A, Silver CE, Rinaldo A, Kim H, Shaha AR. Parastomal recurrence: a therapeutic challenge. Acta Otolaryngol 2002; 122: 222-9.
72. Piquet JJ. Traitement chirurgical des réciedives trachéales apres laryngectomie totale. Ann Otolaryngol 1965; 82: 365-7.
73. Batsakis JG, Hybels R, Rice DH. Laryngeal carcinoma: stomal recurrences and distant metastases. In: Alberti PW, Bryce DP, eds. Centennial Conference on Laryngeal Cancer. New York: Apleton-Century-Crofts; 1976. 868-76.
74. Sisson GA Sr. Ogura memorial lecture: mediastinal dissection. Laryngoscope 1989; 99: 1262-6.
75. Stell PM, van den Broek P. Stomal recurrence after laryngectomy: aetiology and management. J Laryngol Otol 1971; 85: 131-40.
76. Baluyot ST Jr, Shumrick DA, Everts EC. "Emergency" laryngectomy. Arch Otolaryngol 1971; 94: 414-7.
77. Herold RE, Tobey RE. Anesthetic considerations for surgery in oral malignant disease. Otolaryngol Clin North Am 1979; 12: 167-74.
78. Webster AC. Anesthesia for operations on the upper airway. Int Anesthesiol Clin 1972; 10: 61-122.
79. DeSanti PRW. The lymphatics of the larynx and their relation to malignant disease of that organ. Lancet 1904; i: 1710-3.
80. Rouvière H. Lymphatics du larynx. In: Rouvière H, ed. Anatomie des lymphatiques de l'homme. Paris: Masson; 1932. 110-4.
81. Bailey BJ, Pressman JJ. Dissection of the neck and mediastinum in continuity for carcinoma of the head and neck. Laryngoscope 1964; 74: 828-43.
82. Fisch UP, Sigel ME. Cervical lymphatic system as visualized by lymphography. Ann Otol 1964; 73: 869-82.
83. Welsh LW. The normal human laryngeal lymphatics. Ann Otol 1964; 73: 569-82.
84. Welsh LW, Welsh JJ, Behlke FM. Surgical alterations of the laryngeal lymphatics. Ann Otol 1961; 70: 52-63.
85. Welsh LW, Welsh JJ. Abnormal patterns of the laryngeal lymphatics. Laryngoscope 1963; 73: 569-82.
86. Welsh LW, Welsh JJ. Cervical lymphatics: pathologic conditions. Ann Otol 1966; 75: 176-91.
87. Ormerod FC. The management of cancer of the larynx. J Laryngol Otol 1954; 68: 1-27.
88. Alexander FW, Cassady CL. 306 laryngeal carcinomas: staging and end results. Arch Otolaryngol 1966; 83: 602-6.
89. Tucker JA. Application of mediastinoscopy to carcinoma of the larynx: a preliminary report. Laryngoscope 1969; 79: 118-24.
90. Harrison DFN. Pathology of hypopharyngeal cancer in relation to surgical management. J Laryngol Otol 1970; 84: 349-67.
91. Harrison DFN. The pathology and management of subglottic cancer. Ann Otol 1971; 80: 6-12.
92. Abramson AL, Parisier SC, Zamansky MJ, Sulka M. Distant metastases from carcinoma of the larynx. Laryngoscope 1971; 81: 1503-11.
93. Martins AS. Neck and mediastinal node dissection in pharyngolaryngoesophageal tumors. Head Neck 2001; 23: 772-9.
94. Antonelli A, Oldini C, Leonardelli GB. Le recidive peristomali: aspetto anatomo-patologici. Minerva Otolaringol 1980; 30: 39.
95. Pressman JJ, Simon MB. Experimental evidence of direct communication between lymph nodes and veins. Surg Gynecol Obstet 1961; 113: 537-42.
96. Pressman JJ, Simon MB, Hand K, Miller J. Passage of fluids, cells, and bacteria via direct communication of cancer of the larynx. Surg Gynecol Obstet 1962; 115: 207-14.
97. Pressman JJ, Dunn RF, Burtz M. Lymph node ultrastructure related to direct lymphaticovenous communication. Surg Gynecol Obstet 1967; 124: 963-73.
98. Dettman PM, King ER, Zimberg YH. Evaluation of lymph node function following irradiation or surgery. Am J Roentgenol Radium Ther Nucl Med 1966; 96: 711-8.
99. Engeset A. Local irradiation of lymph nodes in rats. Morphological and functional alterations with relation to cancer therapy. Prog Exp Tumor Res 1966; 8: 225-70.
100. Sinha BK, Goldenberg GJ. Effect of irradiation on lymph flow and filtration function of lymph nodes. Cancer 1970; 26: 1239-45.
101. Herman PG, Benninghoff DL, Mellins HZ. Radiation effect on the barrier function of the lymph node. An experimental study. Radiology 1968; 91: 698-702.
102. Sherman JO, O'Brien PH. Effect of ionizing irradiation on normal lymphatic vessels and lymph nodes. Cancer 1967; 20: 1851-8.
103. Ogura JH. Surgical pathology of cancer of the larynx. Laryngoscope 1955; 65: 867-926.
104. Harrison DFN. Thyroid gland in the management of laryngopharyngeal cancer. Arch Otolaryngol 1973; 97: 301-2.
105. Bahadur S, Iyer S, Kacher SK. The thyroid gland in the management of carcinoma of the larynx and laryngopharynx. J Laryngol Otol 1985; 99: 1251-3.
106. Biel MA, Maisel RH. Indications for performing hemithyroidectomy for tumors requiring total laryngectomy. Am J Surg 1985; 150: 435-9.
107. Slaughter DP. The multiplicity of origin of malignant tumors: collective review. Int Abstr Surg 1944; 79: 89-98.
108. Slaughter DP. Multicentric origin of intraoral carcinoma. Surgery 1946; 20: 133-46.
109. Slaughter DP, Southwick HW, Smejkal W. "Field cancerization" in oral stratified squamous epithelium: clinical implications of multicentric origin. Cancer 1953; 6: 963-8.
110. Sirtori C, Leonardelli GB, Parolari P. Plurifocalitá del cancro laringeo e significato di recidiva: studio istopatologico su cento casi. Arch Ital Otol 1963; 74: 483-98.
111. Ballantyne AJ. Principles of surgical management of cancer of the pharyngeal walls. Cancer 1967; 20: 663-7.
112. Knudtson KP. The pathologic effects of smoking tobacco on the trachea and bronchial mucosa. Am J Clin Pathol 1960; 33: 310-7.
113. Auerbach O, Stout AP, Hammond EC, Garfinkel L. Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer. N Engl J Med 1961; 265: 253-67.
114. Moertel CG. Incidence and significance of multiple primary malignant neoplasms. Ann N Y Acad Sci 1964; 114: 886-95.
115. Boice JD Jr, Fraumeni JF Jr. Second cancers following cancer of the respiratory system in Connecticut, 1935-1982. In: Breenwald P, ed. Multiple primary cancer in Connecticut and Denmark. Bethesda, MD: National Cancer Institute Monographs, 1985: 83-98.
116. Olsen JH. Second cancer following cancer of the respiratory system in Denmark, 1943-80. In: Greenwald P, ed. Multiple primary cancer in Connecticut and Denmark. Bethesda, MD: National Cancer Institute Monographs, 1985: 309-24.
117. Franco EL, Kowalski LP, Kanda JL. Risk factors for second cancers of the upper respiratory and digestive systems: a case-control study. J Clin Epidemiol 1991; 44: 615-25.
118. Cahan WG. Lung cancer associated with cancer primary in other sites. Am J Surg 1955; 89: 494-514.
119. Ochoa LAO, Bendito AS. Neoplasias primitivas dobles en el tracto respiratorio. Rev Clin Esp 1984; 173: 215-7.
120. Rinaldo A, Marchiori C, Faggionato L, Saffiotti U, Ferlito A. The association of cancers of the larynx with cancers of the lung. Eur Arch Otorhinolaryngol 1996; 253: 256-9.
121. Incze J, Vaughan CW Jr, Lui P, Strong MS, Kulapaditharom B. Premalignant changes in normal appearing epithelium in patients with squamous cell carcinoma of the upper aerodigestive tract. Am J Surg 1982; 144: 401-5.
122. Griffith TE, Friedberg SA. Histologic changes in the trachea following laryngectomy. Ann Otol 1964; 73: 883-92.
123. Watson WL. Cancer of trachea fifteen years after treatment for cancer of larynx. J Thorac Surg 1942; 12: 142-50.
124. Hajdu SI, Huvos AG, Goodner JT, Foote FW Jr, Beattie EJ Jr. Carcinoma of the trachea. Clinicopathologic study of 41 cases. Cancer 1970; 25: 1448-56.
125. Brown M. Second primaries in cases of cancer of the larynx. J Laryngol Otol 1978; 92: 991-6.
126. Miyahara H, Yoshino K, Umatani K, Sato T. Multiple primary tumours in laryngeal cancer. J Laryngol Otol 1985; 99: 999-1004.
127. Pinotti HW, Gemperli R, Raia A. Carcinoma epidermóide de pele por uso prolongado de gastrostomia. Rev Paul Med 1978; 92: 118-20.
128. Weissman RA, Konrad HR. Tracheal carcinoma after tracheostomy. Arch Otolaryngol 1979; 105: 364-6.
129. de Aquino JLB, de Aquino Neto PA. Carcinoma epidermóide de pele por uso prolongado de traqueostomia. Rev Paul Med 1986; 104: 110.
130. Warren GH, Pearlman NW, Cain TL. Carcinoma arising in a tracheostomy scar. Arch Otolaryngol 1983; 109: 352-3.
131. Sisson GA, Bytell DE, Becker SP. Mediastinal dissection - 1976: indications and newer techniques. Laryngoscope 1977; 87: 751-9.
132. Vermund H. Role of radiotherapy in cancer of the larynx as related to the TNM system of staging. A review. Cancer 1970; 25: 485-504.
133. Davis RK, Shapshay SM. Peristomal recurrence: pathophysiology, prevention, treatment. Otolaryngol Clin North Am 1980; 13: 499-508.
134. Chiesa F, Tradati N, Calabrese L, et al. Surgical treatment of laryngeal carcinoma with subglottis involvement. Oncol Rep 2001; 8: 137-40.
135. Harrison DFN. Surgical management of hypopharyngeal cancer: particular reference to the gastric "pull-up" operation. Arch Otolaryngol 1979; 105: 149-52.
136. Norris CM, Kuo BF, Tucker GF Jr, Pitser WF. A correlation of clinical staging, pathological findings and five year end results in surgically treated cancer of the larynx. Ann Otol 1970; 79: 1033-48.
137. Kirchner JA, Cornog JL Jr, Holmes RE. Transglottic cancer. Its growth and spread within the larynx. Arch Otolaryngol 1974; 99: 247-51.
138. Micheau C, Luboinski B, Sancho H, Cachin Y. Modes of invasion of cancer of the larynx. A statistical, histological, and radioclinical analysis of 120 cases. Cancer 1976; 38: 346-60.
139. Som ML. Surgical treatment of carcinoma of post-cricoid region. N Y State J Med 1961; 61: 2567-76.
140. Pietrantoni L, Agazzi C, Fior R. Indications for surgical treatment of cervical lymphonodes in cancer of the larynx and hypopharynx. Laryngoscope 1962; 72: 1511-27.
141. Harrison DFN. Role of surgery in the management of postcricoid and cervical esophageal neoplasms. Ann Otol 1972; 81: 465-8.
142. Harrison DFN. Laryngectomy for subglottic lesions. Laryngoscope 1975; 85: 1208-10.
143. Shaha AR, Shah JP. Carcinoma of the subglottic larynx. Am J Surg 1982; 144: 456-8.
144. Harris HH, Butler E. Surgical limits in cancer of the subglottic larynx. Arch Otolaryngol 1968; 87: 490-3.
145. Kowalski LP, Franco ELF, de Andrade Sobrinho J, Oliveira BV, Pontes PAL. Prognostic factors in laryngeal cancer patients submitted to surgical treatment. J Surg Oncol 1991; 48: 87-95.
146. Stell PM, Bickford BJ, Brown GA. Thoracotracheostomy after resection of the larynx and cervical trachea for cancer. J Laryngol 1970; 84: 1097-102.
147. Tong D, Moss WT, Stevens KR Jr. Elective irradiation of the lower cervical region in patients at high risk for recurrent cancer at the tracheal stoma. Radiology 1977; 124: 809-11.
148. Mirimanoff RO, Wang CC, Doppke KP. Combined surgery and postoperative radiation therapy for advanced and laryngeal and hypopharyngeal carcinomas. Int J Radiat Oncol Biol Phys 1985; 11: 499-504.
149. Sisson GA, Strahley CJ Jr, Johnson NE. Mediastinal dissection for recurrent cancer after laryngectomy. Laryngoscope 1962; 72: 1064-77.
150. Johnson NE, Sisson GA. Carcinoma of the larynx: review of 100 cases. Laryngoscope 1964; 74: 710-22.
151. Sisson GA. Mediastinal dissection for recurrent cancer after laryngectomy. Trans Am Acad Ophthalmol Otolaryngol 1970; 74: 767-77.
152. Sisson GA, Bytell DE, Edison BD, Yeh S Jr. Transsternal radical neck dissection for control of stomal recurrences-end results. Laryngoscope 1975; 85: 1504-10.
153. Sisson GA, Goldman ME. Pectoral myocutaneous island flap for reconstruction of stomal recurrence. Arch Otolaryngol 1981; 107: 446-9.
154. Krespi YP, Wurster CF, Sisson GA. Immediate reconstruction after total laryngopharyngoesophagectomy and mediastinal dissection. Laryngoscope 1985; 95: 156-61.
155. Atiyah RA, Shindo M, Sisson GA Sr. Mediastinal dissection and gastric pull-up. Otolaryngol Clin North Am 1991; 24: 1287-94.
156. Ujiki GT, Pearl GJ, Poticha S, Sisson GA Sr, Shields TW. Mortality and morbidity of gastric "pull-up" for replacement of the pharyngoesophagus. Arch Surg 1987; 122: 644-7.
157. Sisson GA. Mediastinal dissection - resectability and curability of stomal recurrence after total laryngectomy. Auris Nasus Larynx 1985; 12(Suppl 2): S61-6.
158. Cordeiro PG, Mastorakos DP, Shaha AR. The radial forearm fasciocutaneous free-tissue transfer for tracheostomy reconstruction. Plast Reconstr Surg 1996; 98: 354-7.