Al3+-mediated changes on membrane fluidity affects the activity of PI-PLC but not of PLC

Chemistry and Physics of Lipids

Volumn 122, Issue 1-2, 2003, Pages 159-163

  Verstraeten, Sandra V ^a   Villaverde, Marcela S ^a   Oteiza, Patricia I ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Aluminum; Fluidity; Membranes; Phosphoinositides; Phospholipase; PI PLC; PLC

Indexed keywords

1,6 DIPHENYL 1,3,5 HEXATRIENE; ALUMINUM; LAURDAN; LIPOSOME; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; PHOSPHOLIPASE C PHOSPHATIDYLINOSITOL; POLYPHOSPHOINOSITIDE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; HYDROLYSIS; MEMBRANE FLUIDITY; MOLECULAR PROBE; PRIORITY JOURNAL; PROTEIN INTERACTION;

ALUMINUM; FLUORESCENCE POLARIZATION; HYDROLYSIS; LIPOSOMES; MEMBRANE FLUIDITY; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE; PHOSPHOLIPASE C;

PROKARYOTA;

EID: 0037277581     PISSN: 00093084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-3084(02)00192-5     Document Type: Conference Paper

References (11)

1. Chen P.S. Jr., Toribara T.Y., Warner H. Microdetermination of phosphorus. Anal. Chem. 28:1956;1756-1758.
2. 3+ induce phase separation, aggregation and dye release in phosphatidylserine-containing lipid vesicles. Biochim. Biophys. Acta. 813:1985;195-200.
3. Katan M. Families of phosphoinositide-specific phospholipase C: structure and function. Biochim. Biophys. Acta. 1436:1998;5-17.
4. Martin B.R. The chemistry of aluminum as related to biology and medicine. Clin. Chem. 32:1986;1797-1806.
5. Nostrandt A.C., Shafer T.J., Mundy W.R., Padilla S. Inhibition of rat brain phosphatidylinositol-specific phospholipase C by aluminum: regional differences, interactions with aluminum salts, and mechanisms. Toxicol. Appl. Pharmacol. 136:1996;118-125.
6. Parasassi T., DeStasio G., d'Ubaldo A., Gratton E. Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence. Biophys. J. 57:1990;1179-1186.
7. Shafer T.J., Mundy W.R. Effects of aluminum on neuronal signal transduction: mechanisms underlying disruption of phosphoinositide hydrolysis. Gen. Pharmac. 26:1995;889-895.
8. Shafer T.J., Mundy W.R., Wilson H.A. Aluminium decreases muscarinic, adrenergic, and metabotropic receptor-stimulated phosphoinositide hydrolysis in hippocampal and cortical slices from rat brain. Brain Res. 629:1993;133-140.
9. 3+-mediated lipid oxidation. Effect of galactolipids. Biochem. J. 333:1998;833-838.
10. Verstraeten S.V., Nogueira L.V., Schreier S., Oteiza P.I. Effect of trivalent metal ions on phase separation and membrane lipid packing: role in lipid peroxidation. Arch. Biochem. Biophys. 338:1997;121-127.
11. 3+ and related metals on membrane phase state and hydration: correlation with lipid oxidation. Arch. Biochem. Biophys. 375:2000;340-346.