Nephrotoxic effects of mercury exposure and smoking among Egyptian workers in a fluorescent lamp fac1tory

Archives of Medical Research

Volumn 34, Issue 1, 2003, Pages 50-55

  El Safty, Ibrahim A M ^a,d   Shouman, Ahmed E ^b   Amin, Nour E ^c  

^a Ain Shams University   (Egypt)

^b AIN SHAMS UNIVERSITY   (Egypt)

^c HOT LABORATORIES CENTER   (Egypt)

^d MAKERERE UNIVERSITY   (Uganda)

Author keywords

Glutathione S transferase (GST); Leucine aminopeptidase (LAP); N Acetyl D glucosaminidase (NAG); Retinol binding protein (RBP); Total protein (TP)

Indexed keywords

CREATINE; CYTOSOL AMINOPEPTIDASE; GLUTATHIONE TRANSFERASE; MERCURY; N ACETYL BETA GLUCOSAMINIDASE; RETINOL BINDING PROTEIN;

ADULT; ARTICLE; CIGARETTE SMOKING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE URINE LEVEL; EGYPT; ELECTRONICS INDUSTRY; HEAVY METAL POISONING; HUMAN; INDUSTRIAL WORKER; KIDNEY EXAMINATION; KIDNEY INJURY; MALE; MAXIMUM ALLOWABLE CONCENTRATION; NEPHROTOXICITY; OCCUPATIONAL EXPOSURE; PROTEIN URINE LEVEL; RANDOMIZATION; URINALYSIS; URINARY EXCRETION;

EGYPT; ENVIRONMENTAL MONITORING; HUMANS; KIDNEY; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MERCURY; MERCURY POISONING; OCCUPATIONAL EXPOSURE; SMOKING; STATISTICS; TIME FACTORS;

EID: 0037277464     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0188-4409(02)00462-9     Document Type: Article

References (45)

1. Weiss B. Perspectives on methylmercury as a global hazard. Neurotoxicology. 16:1995;577-578.
2. Zalupus R.K. Influence of 2,3-dimercaptopropane-1-sulfonate (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA) on the renal disposition of mercury in normal and un-nephrectomized rats exposed to inorganic mercury. J Pharmacol Exp Ther. 267:1993;791-800.
3. Zalupus R.K., Lash L.H. Advances in understanding the renal transport and toxicity of mercury. J Toxicol Environ Health. 42:1994;1-44.
4. Barfuss D.W., Robinson M.K., Zalupus R.K. Inorganic mercury transport in the proximal tubule of the rabbit. J Am Soc Nephrol. 1:1990;910-917.
5. Zalupus R.K., Barfuss D.W. Accumulation of inorganic mercury along the renal proximal tubule of the rabbit. Toxicol Appl Pharmacol. 106:1990;245-253.
6. Ehrenberg R.L., Vogt R.L., Smith A.B., Brondum J., Brightwell W.S., Hudson P.J., McManus K.P., Hannon W.H., Phipps F.C. Effects of elemental mercury exposure at a thermometer plant. Am J Ind Med. 19:1991;495-507.
7. Cárdenas A., Roels H., Bernard A.M., Barbón R., Buchet J.P., Lauwerys R.R., Roselló J., Hotter G., Mutti A., Franchini I., Fels L.M., Stolte H., DeBroe M.E., Nuyts G.D., Taylor S.A., Price R.G. Markers of early renal changes induced by industrial pollutants. I. Application to workers exposed to mercury vapours. Br J Ind Med. 50:1993;17-27.
8. Molin M., Schutz A., Skerfving S., Sallsten G. Mobilized mercury in subjects with varying exposure to elemental mercury vapour. Int Arch Occup Environ Health. 63:1991;187-192.
9. nd ed:1988;Year Book Medical Publishers, Chicago, IL, USA. 590-596.pp.
10. ACGIH (1993-1994) Threshold limit values for chemical substances and physical agents and biological exposure indices. 1994;ACGIH, Cincinnati, OH, USA.
11. Lauwerys R., Bernard A., Cárdenas A. Monitoring of early nephrotoxic effects of industrial chemicals. Toxicol Lett. 64-65:1992;N33-N42.
12. Mueller P.W., Lash L.H., Price R.G., Stolte H., Gelpi E., Maack T., Berndt W.O. Urinary biomarkers to detect significant effects of environmental and occupational exposure to nephrotoxins. I. Categories of tests for detecting effects of nephrotoxins. Renal Fail. 19:1997;505-521.
13. Zuppi C., Baroni S., Scribano D., Di Salvo S., Musumeci V. Choice of time for urine collection for detecting early kidney abnormalities in hypertensives. Ann Clin Biochem. 32(pt 4):1995;373-378.
14. Watanabe N., Kamei S., Ohkubo A., Yamakna M., Ohsawa S., Makino K., Tokuda K. Urinary protein as measured with a pyrogallol red-molybdata complex, manually and in a Hitachi 726 automated analyzer. Clin Chem. 32:1986;1551-1554.
15. Jösch W., Dubach D.U. Urine-arylamidase. Z Klin Chem. 5:1967;59-63.
16. Goldstein E.J., Feinfeld D.A., Fleischner G.M., Elkin M. Enzymatic evidence of renal tubular damage following renal angiography. Radiology. 121:1976;617-619.
17. Thomas G.H. β-D-galactosidase in human urine. deficiency in generalized gangliosidosis J Lab Clin Med. 74(5):1969;725-731.
18. Bartels H., Böhmer M., Heieli C. Serum kreatinibestimmung ohne enteiweissen. Clin Chim Acta. 37:1972;193-197.
19. Lemann J. Jr., Dowmans B.T. Proteinuria in health and disease assessed by measuring the urinary protein/creatinine ratio. Clin Chem. 33:1987;297-299.
20. Jung K. Enzyme activities in urine. How should we express their excretion? Eur J Clin Chem Clin Biochem. 29:1991;725-729.
21. Martin M.D., McCann T., Naleway C., Woods J.S., Leroux B.G., Bollen A.-M. The validity of spot urine samples for low-level occupational mercury exposure assessment and relationship to porphyrin and creatinine excretion rates. J Pharmacol Exp Ther. 277:1996;239-244.
22. El-Safty I.A.M., Shouman A.E., Anwar S.M. Early detection of nephrotoxicity effects due to low-dose exposure of cadmium among cigarette smokers. J Egypt Public Health Assoc. LXXI(1,2):1996;9-29.
23. Buchet J.P., Roels H., Bernard A., Lauwerys R.R. Assessment of renal function of workers exposed to inorganic lead, cadmium or mercury vapour. J Occup Med. 22:1980;741-750.
24. Roels H., Lauwerys R., Buchet J.P., Bernard A., Barthels A., Oversteyns M., Gaussin J. Comparison of renal function and psychomotor performance in workers exposed to elemental mercury. Int Arch Occup Environ Health. 50:1982;77-93.
25. Verschoor M.A., Herber R.F.M., Zielhuis R.L. Urinary mercury levels and early changes in kidney function in dentists and dental assistants. Community Dent Oral Epidemiol. 16:1988;148-152.
26. Tubbs R.R., Gephardt G.N., McMahon J.T., Pohl M.C., Vidt D.G., Barenberg S.A., Valenzuela R. Membranous glomerulonephritis associated with industrial mercury exposure. Am J Clin Pathol. 77:1982;409-413.
27. Lauwerys R.L., Bernard A.M., Roels H.R., Buchet J.P., Gennart J.P., Mahieu P., Foidart J.M. Anti-laminin antibodies in workers exposed to mercury vapour. Toxicol Lett. 17:1983;113-116.
28. Bencko V., Wagner V., Wagnerova M., Ondrejcak V. Immunological profiles in workers occupationally exposed to inorganic mercury. J Hyg Epidemiol Microbiol Immunol. 34:1990;293-306.
29. Hultman P., Eneström S. Mercury induced B-cell activation and antinuclear antibodies in mice. J Clin Lab Immunol. 28:1989;143-150.
30. Weening J., Grond J., Van der Top D., Hoedemaeker J. Identification of the nuclear antigen involved in mercury-induced glomerulopathy in the rat. Invest Cell Pathol. 3:1980;129-134.
31. Roels H., Gennart J.P., Lauwerys R., Buchet J.P., Malchaire J., Bernard A. Surveillance of workers exposed to mercury vapour. validation of a previously proposed biological threshold limit value for mercury concentration in urine Am J Ind Med. 7:1985;45-71.
32. Price R.G., Whiting P.H. Urinary enzymes and nephrotoxicity in humans. Jung K., Mattenheimer H., Burchardt U. Urinary enzymes in clinical and experimental medicine. 1992;Springer-Verlag, Berlin, Germany. 203-221.pp.
33. Planas-Bohne F. The effect of mercuric chloride on the excretion of two urinary enzymes in the rat. Arch Toxicol. 37(3):1977;219-225.
34. Price R.G., Kempson S.A. The effect of mercuric chloride on rat kidney cortical plasma membranes. Biochem Soc Trans. 3:1975;294-296.
35. Backman L., Appelkvist E.L., Ringden O., Dallner G. Urinary levels of basic glutathione transferase as an indicator of proximal tubular damage in renal transplant recipients. Transplant Proc. 21:1989;1514-1516.
36. El-Safty I.A.M., Anwar S.M., Shouman A.E. Levels of some metal contents of different cigarette brands available in the Egyptian market and the effect of cigarette smoking on blood or serum concentrations of these metals among cigarette smokers. Mansoura Sci Bull (A Chem). 24(1(Suppl 2)):1997;65-84.
37. Oberley T., Friedman A., Moser R., Siegel F.L. Effects of lead administration on developing rat kidney. II. Functional, morphologic and immunohistochemical studies. Toxicol Appl Pharmacol. 131:1995;94-107.
38. McGuire S., Daggett D.A., Bostad E., Nelson S., Wright Siegel F.L., Kornguth S. Increased levels of glutathione S-transferases and appearance of novel alpha class isoenzymes in kidneys of mice exposed to mercuric chloride. I. Biochemical and immunohistochemical studies. Nephron. 77(4):1997;452-460.
39. Backman L., Appelkvist E.L., Ringen O., Dallner G. Glutathione transferase in the urine. a marker for post-transplant tubular lesions Kidney Int. 33:1988;571-577.
40. nd ed:1993;Raven Press, New York. 437-457.pp.
41. Olsen S. Acute tubular necrosis and toxic renal injury. Tisher C.C., Brenner B.M. Renal pathology. 1989;Lippincott, Philadelphia, PA, USA. 669.pp.
42. Suzuki T., Morimura S., Diccianni M.B., Yamada R., Hochi S., Hirabayashi M., Yuki A., Nomura K., Kitagawa T., Imagawa M., Muramatsu M. Activation of glutathione transferase p gene by lead requires glutathione transferase p enhancer. J Biol Chem. 271:1996;1626-1632.
43. Boogaard P.J., Houtsma A.-T.A.J., Journée H.L., Van Sittert N.J. Effects of exposure to elemental mercury on the nervous system and the kidneys of workers producing natural gas. Arch Environ Health. 51(2):1996;108-115.
44. Langworth S., Elinder C.G., Sundquist K.G., Vesterberg O. Renal and immunological effects of occupational exposure to inorganic mercury. Br J Ind Med. 49(6):1992;394-401.
45. WHO Inorganic mercury. Environmental health criteria 118. 1991;1-115 WHO, Geneva, Switzerland.