Regulation of caldesmon activity by Cdc2 kinase plays an important role in maintaining membrane cortex integrity during cell division

Cellular and Molecular Life Sciences

Volumn 60, Issue 1, 2003, Pages 198-211

  Li, Y ^a   Wessels, D ^a   Wang, T ^a   Lin, J L C ^a   Soll, D R ^a   Lin, J J C ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

2D and 3D dynamic image analysis; Blebbing; Cytokinesis; Microfilament; Mitosis specific phosphorylation; Phosphorylation defective mutant

Indexed keywords

CALDESMON; PROTEIN KINASE;

AMINO TERMINAL SEQUENCE; ANAPHASE; ARTICLE; CELL DIVISION; CONTROLLED STUDY; CYTOKINESIS; ENZYME ACTIVITY; GENE OVEREXPRESSION; MEMBRANE STRUCTURE; MITOSIS; MUTANT; NONHUMAN; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; WILD TYPE;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; CALMODULIN-BINDING PROTEINS; CDC2 PROTEIN KINASE; CELL DIVISION; CELL MEMBRANE; CELL SIZE; CHO CELLS; CRICETINAE; FIBROBLASTS; GENE EXPRESSION; HUMANS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; POINT MUTATION; TIME FACTORS; TROPOMYOSIN;

EID: 0037275128     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000180300014     Document Type: Article

References (40)

1. Bretscher A. (1986) Thin filament regulatory proteins of smooth- and non-muscle cells. Nature 321: 726-728
2. Huber P. A. (1997) Caldesmon. Int. J. Biochem. Cell Biol. 29: 1047-1051
3. Marston S. B. and Redwood C. S. (1991) The molecular anatomy of caldesmon. Biochem. J. 279: 1-16
4. Matsumura F. and Yamashiro S. (1993) Caldesmon. Curr. Opin. Cell Biol. 5: 70-76
5. Sobue K. and Sellers J. (1991) Caldesmon, a novel regulatory protein in smooth muscle and nonmuscle actomyosin systems. J. Biol. Chem. 266: 12115-12118
6. Galazkiewicz B., Belagyi J. and Dabrowska R. (1989) The effect of caldesmon on assembly and dynamic properties of actin. Eur. J. Biochem. 181: 607-614
7. Ikebe M. and Reardon S. (1988) Binding of caldesmon to smooth muscle myosin. J. Biol. Chem. 263: 3055-3058
8. Novy R. E., Sellers J. R., Liu L.-F. and Lin J. J.-C. (1993) In vitro functional characterization of bacterially expressed human fibroblast tropomyosin isoforms and their chimeric mutants. Cell Motil. Cytoskel. 26: 248-261
9. Yamashiro-Matsumura S. and Matsumura F. (1988) Characterization of 83-kilodalton nonmuscle caldesmon from cultured rat cells: stimulation of actin binding of nonmuscle tropomyosin and periodic localization along microfilaments like tropomyosin. J. Cell Biol. 106: 1973-1983
10. Ishikawa R., Yamashiro S. and Matsumura F. (1989) Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin: potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon. J. Biol. Chem. 264: 7490-7497
11. 2-. J. Biol. Chem. 264: 16764-16770
12. Ishikawa R., Yamashiro S., Kohama K. and Matsumura F. (1998) Regulation of actin binding and actin bundling activities of fascin by caldesmon coupled with tropomyosin. J. Biol. Chem. 273: 26991-26997
13. Earley J. J., Su X. and Moreland R. S. (1998) Caldesmon inhibits active crossbridges in unstimulated vascular smooth muscle: an antisense oligodeoxynucleotide approach. Circ. Res. 83: 661-667
14. Yamashiro S., Chen H., Yamakita Y. and Matsumura F. (2001) Mutant caldesmon lacking cdc2 phosphorylation sites delays M-phase entry and inhibits cytokinesis. Mol. Biol. Cell 12: 239-250
15. Helfman D. M., Levy E. T., Berthier C., Shtutman M., Riveline D., Grosheva I. et al. (1999) Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions. Mol. Biol. Cell 10: 3097-3112
16. ++/calmodulin-, and tropomyosin-binding domains stabilizes endogenous tropomyosin and microfilaments. J. Cell Biol. 125: 359-368
17. Warren K. S., Shutt D. C., McDermott J. P., Lin J. L.-C., Soll D. R. and Lin J. J.-C. (1996) Overexpression of microfilament-stabilizing human caldesmon fragment, CAD39, affects cell attachment, spreading, and cytokinesis. Cell Motil. Cytoskel. 34: 215-229
18. Fraser I. D. C. and Marston S. B. (1995) In vitro motility analysis of smooth muscle caldesmon control of actin-tropomyosin filament movement. J. Biol. Chem. 270: 19688-19693
19. Haeberle J. R., Trybus K. M., Hemric M. E. and Warshaw D. M. (1992) The effects of smooth muscle caldesmon on actin filament motility. J. Biol. Chem. 267: 23001-23006
20. Horiuchi K. Y. and Chacko S. (1995) Effect of unphosphorylated smooth muscle myosin on caldesmon-mediated regulation of actin filament velocity. J. Muscle Res. Cell Motil. 16: 11-19
21. Okagaki T., Higashi-Fujime S., Ishikawa R., Takama-Ohmuro H. and Kohama K. (1991) In vitro movement of actin filaments on gizzard smooth muscle myosin: requirement of phosphorylation of myosin light chain and effects of tropomyosin and caldesmon. J. Biochem. 109: 858-866
22. Shirinsky V. P., Biryukov K. G., Hettasch J. M. and Sellers J. (1992) Inhibition of the relative movement of actin and myosin by caldesmon and calponin. J. Biol. Chem. 267: 15886-15892
23. Yamakita Y., Yamashiro S. and Matsumura F. (1992) Characterization of mitotically phosphorylated caldesmon. J. Biol. Chem. 267: 12022-12029
24. Yamashiro S., Yamakita Y., Ishikawa R. and Matsumura F. (1990) Mitosis-specific phosphorylation causes 83k non-muscle caldesmon to dissociate from microfilaments. Nature 344: 675-678
25. cdc2 kinase during mitosis. Nature 349: 169-172
26. Hosoya N., Hosoya H., Yamashiro S., Mohri H. and Matsumura F. (1993) Localization of caldesmon and its dephosphorylation during cell division. J. Cell Biol. 121: 1075-1082
27. Yamashiro S., Yamakita Y., Yoshida K., Takiguchi K. and Matsumura F. (1995) Characterization of the COOH terminus of non-muscle caldesmon mutants lacking mitosis-specific phosphorylation sites. J. Biol. Chem. 270: 4023-4030
28. -+/calmodulin and to actin or actin-tropomyosin filaments. Cell Motil. Cytoskel. 20: 95-108
29. ++, KCl, troponin I, and troponin C. Biochemistry 14: 2718-2724
30. Matsumura F., Yamashiro-Matsumura S. and Lin J. J.-C. (1983) Isolation and characterization of tropomyosin-containing microfilaments from cultured cells. J. Biol. Chem. 258: 6636-6644
31. Soll D. R. (1995) The use of computers in understanding how animal cells crawl. Int. Rev. Cytol. 8: 439-454
32. Soll D. R. and Voss E. (1998) Two- and three-dimensional computer systems for analyzing how cells crawl. In: Motion Analysis of Living Cells, pp. 25-52, Soll D. R. and Wessels D. (eds), Wiley, New York
33. Soll D. R., Voss E., Johnson O. and Wessels D. J. (2000) Three-dimensional reconstruction and motion analysis of living crawling cells. Scanning 22: 249-257
34. Wong K., Wessels D., Krob S. L., Matveia A. R., Lin J. L.-C., Soll D. R. et al. (2000) Forced expression of a dominant-negative chimeric tropomyosin causes abnormal motile behavior during cell division. Cell Motil. Cytoskel. 45: 121-132
35. Wessels D., Voss E., Bergen N. von, Burns R., Stites J. and Soll D. R. (1998) A computer-assisted system for reconstructing and interpretating the dynamic three-dimensional relationships of the outer surface, nucleus, and pseudopods of crawling cells. Cell Motil. Cytoskel. 41: 225-246
36. Pasternak C., Spudich J. A. and Elson E. L. (1989) Capping of surface receptors and concomitant cortical tension are generated by conventional myosin. Nature 341: 549-551
37. Tsai M. A., Frank R. S. and Waugh R. E. (1994) Passive mechanical behavior of human neutrophils. Biophys. J. 66: 2166-2172
38. Dai J., Ting-Beall H. P., Hochmuth R. M., Sheetz M. P. and Titus M. A. (1999) Myosin I contributes to the generation of resting cortical tension. Biophys. J. 77: 1168-1176
39. McManus M. J., Lingle W. L., Salisbury J. L. and Maihle N. J. (1997) A transformation-associated complex involving tyrosine kinase signal adaptor proteins and caldesmon links v-ErbB signaling to actin stress fiber disassembly. Proc. Natl. Acad. Sci. USA 94: 11351-11356
40. Li C. J., Heim R., Lu P., Pu Y., Tsien R. Y. and Chang D. C. (1999) Dynamic redistribution of calmodulin in HeLa cells during cell division as revealed by a GFP-calmodulin fusion protein technique. J. Cell Sci. 112: 1567-1577