The neurite-stimulating influence of components of medicinal leech salivary gland secretions in organotypic culture of spinal ganglia

Neuroscience and Behavioral Physiology

Volumn 33, Issue 1, 2003, Pages 85-88

  Chalisova, N I ^a   Baskova, I P ^c   Zavalova, L L ^b   Pennijainen, V A ^a  

^a PAVLOV INSTITUTE OF PHYSIOLOGY   (Russian Federation)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Medicinal leech; Nerve tissue culture; Protease inhibitors

Indexed keywords

BDELLIN A; BDELLIN B; DESTABILASE; HIRUDIN; PIYAVIT; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; EMBRYO; LEECH; NERVE GROWTH; NERVE STIMULATION; NEURITE; NONHUMAN; REVERSED PHASE LIQUID CHROMATOGRAPHY; SALIVARY GLAND; SPINAL GANGLION; TISSUE CULTURE;

ANIMALS; BIOLOGICAL FACTORS; CHICK EMBRYO; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; FIBRINOLYTIC AGENTS; GANGLIA, SPINAL; LEECHES; NEURITES; ORGAN CULTURE TECHNIQUES; ORGANIC CHEMICALS; PROTEASE INHIBITORS; PROTEINS; SALIVARY GLANDS; SERPINS;

EID: 0037274563     PISSN: 00970549     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021187500632     Document Type: Article

References (14)

1. I. P. Baskova and G. I. Nikonov "Destabilase - An enzyme from medicinal leech salivary gland secretion which hydrolyses isopeptide bonds in stabilized fibrin," Biokhimiya, 50, No. 4, 424-431 (1985).
2. V. P. Goncharova, N. I. Chalisova, A. V. Romanyuk, G. N. Akoev, and E. N. Chumasov, "The neurite-stimulating activity of brain tissue serine proteases in tissue culture," Dokl. Akad. Nauk USSR, 285, No. 2, 1238-1241 (1985).
3. G. S. Isakhanyan, Hirudotherapy in Clinical Practice in Internal Diseases [in Russian], Aiastan, Erevan (1991).
4. A. I. Krashenyuk, S. V. Krashenyuk, and N. I. Chalisova, "A neurotrophic factor from Hirudo medicinalis (the medicinal leech)," in: Proceedings of the Fifth Scientific and Applied Conference of the Association of Leech Therapists [in Russian], St. Petersburg, Russia (1997).
5. A. A. Muslyakovskaya, E. L. Khodorov, and T. M. Pozdnyakova, "Extraction of a dimer of fragment D from stabilized fibrin and studies of its antipolymerization effect," Ukr. Biokhim. Zh., 48, No. 2, 139-143 (1976).
6. N. I. Chalisova, V. F. Mel'kishev, G. N. Akoev, M. I. Lyudyno, and T. Yu. Kurenkova, "The neurite-stimulating action of prolactin in organotypic neuron cultures," Tsitologiya, 33, No. 2, 29-31 (1991).
7. V. Kh. Khavinson, V. G. Morozov, N. I. Chalisova, and V. V. Okulov, "The effects of brain peptides on nerve tissue cells in vitro," Tsitologiya, 39, No. 7, (1997).
8. P. Ascenzi, G. Amiconi, W. Bode, M. Bolognese, M. Coletta, and E. Menegatti, "Protease inhibitors from European medicinal leech Hirudo medicinalis: Structural, functional and biomedical aspects," Mol. Aspects Med., 16, 215-313 (1995).
9. Y. Bardem, D. Edgar, and H. Thoenen, "Sensory neurons in culture: Changing requirements for survival factors during embryonic development," Proc. Natl. Acad Sci. USA, 77, 1199-1203 (1980).
10. I. P. Bascova, A. N. Korostelev, L. D. Chirkova, L. L. Zavalova, A. V. Basanova, and Ch. Doutremepuich, "Piyavit from the medicinal leech is a new orally active anticoagulating and antithrombotic drug," Clin. Appl. Thrombosis/Hemostasis, 31, 40-45 (1996).
11. R. Levi-Montalcini, "Developmental neurobiology and the natural history of nerve growth factor," Ann. Rev. Neurosci., 5, 341-362 (1982).
12. M. Manthorpe, S. Scaper, Y. Barde, and S. Varon, "Cholinergic neurotrophic factors (CNTF's): Concurrent activities on certain nerve growth factor-responsive neurons," J. Neurochem., 38, 415-421 (1982).
13. F. Seil, and A. Leiman, "Neural subsystem and learning. Tissue-culture approaches," in Neural Mechanisms and Learning, London (1997).
14. L. Zavalova, S. Lukyanov, I. Bascova, S. Berezhnoy, E. Bogdanova, E. Barsova, and E. Sverdlov, "Genes from the medicinal leech (Hirudo medicinalis) coding for unusual enzymes that specifically cleave endo e(g)-Glu-Lys isopeptide bonds and help to dissolve blood clots," Mol. Gen. Genet., 253, 20-25 (1997).