Correlation of platelet count changes with liver cell destruction in HELLP syndrome

Hypertension in Pregnancy

Volumn 22, Issue 1, 2003, Pages 57-62

  Rychel, Valerie ^a   Williams, Keith P ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AST; HELLP syndrome; Platelet count; Preeclampsia

Indexed keywords

ASPARTATE AMINOTRANSFERASE;

ADULT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL DESTRUCTION; CLINICAL ARTICLE; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DISEASE SEVERITY; FEMALE; HELLP SYNDROME; HUMAN; HUMAN CELL; LIVER CELL DAMAGE; LIVER DYSFUNCTION; PREECLAMPSIA; PUERPERIUM; THROMBOCYTE COUNT;

ADULT; ASPARTATE AMINOTRANSFERASES; FEMALE; HELLP SYNDROME; HUMANS; LIVER; LIVER FUNCTION TESTS; MEDICAL RECORDS; PLATELET COUNT; POSTPARTUM PERIOD; PREGNANCY; RETROSPECTIVE STUDIES;

EID: 0037273093     PISSN: 10641955     EISSN: None     Source Type: Journal    
DOI: 10.1081/PRG-120017004     Document Type: Article

References (15)

1. Weinstein L. Syndrome of hemolysis, elevated liver enzymes and low platelet count: A severe consequence of hypertension in pregnancy. Am J Obstet Gynecol 1982; 142:159-167.
2. Weinstein L. Preeclampsia/eclampsia with hemolysis, elevated liver enzymes and thrombocytopenia. Obstet Gynecol 1985; 66:657-660.
3. Weinstein L. The HELLP syndrome: a severe consequence of hypertension in pregnancy. J Perinatol 1986; 6:316-320.
4. Martin JN, Blake PG, Lowry SL, Perry KG, Files JC, Morrison JC. Pregnancy complicated by preeclampsia-eclampsia with the syndrome of hemolysis, elevated liver enzymes, and low platelet count: how rapid is postpartum recovery? Obstet Gynecol 1990; 76:737-740.
5. Martin JN, Rinehart BK, May WL, Mayann EF, Terrone DA, Blake PG. The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis elevated liver enzymes, and low platelet count) syndrome classification. Am J Obstet Gynecol 1999; 180:1373-1384.
6. Stedman CM, Huddleston JF, Quinlan RW, Huant ST. Thrombocytopenia and transaminase elevation associated with preeclampsia: the rapidity of postpartum improvement [Abstract]. Proceedings of the Seventh Annual Meeting of the Society of Perinatal Obstetricians, Lake Buena Vista, Florida, February 5-7, 1987.
7. Catanzarite V. The pattern and time course of laboratory abnormalities in HELLP syndrome [Abstract]. Proceedings of the Ninth Annual Meeting of the Society of Perinatal Obstetricians, New Orleans, Louisiana, February 2-4, 1989.
8. Neiger R, Contag SA, Coustan DR. The resolution of preeclampsia-related thrombocytopenia [Abstract]. Proceedings of the Tenth Annual Meeting of the Society of Perinatal Obstetricians, Houston, Texas, January 23-27, 1990.
9. Lockitch G. Handbook of diagnostic biochemistry and hematology in normal pregnancy. Gestational Changes in Normal Pregnancy Biochemistry. CRC Press: Boca Raton, FL, 1993.
10. Sibai BM, Taslimi MM, El-Nazer A, Amon E, Mabie BC, Ryan GM. Maternalperinatal outcome associated with the syndrome of hemolysis, elevated liver enzymes, and low platelets in severe preeclampsia-eclampsia. Am J Obstet Gynecol 1986; 155:501-509.
11. Mackenna J, Dover NL, Brame RG. Preeclampsia associated with hemolysis, elevated liver enzymes, and low platelets - An obstetric emergency? Obstet Gynecol 1983; 62:751-754.
12. Thiagarajah S, Bourgeois FJ, Harbert GM, Caudle MR. Thrombocytopenia in preeclampsia: associated abnormalities and management principles. Am J Obstet Gynecol 1984; 150:1-7.
13. Rath W, Faridi A, Dudenhausen JW. HELLP syndrome. J Perinat Med 2000; 28(4):249-260.
14. Makkonen N, Harju M, Kirkinen P. Postpartum recovery after severe pre-eclampsia and HELLP syndrome. J Perinat Med 1996; 24(6):641-649.
15. Rakoczi I, Tallian F, Bogdany S, Gatou I. Platelet Lifespan in Normal Pregnancy and Preeclampsia as Determined by a Non-Radioisotope Technique. Throm Res, 1979; 15:553-556.