Circulating intercellular adhesion molecule-1 in chronic hepatitis C patients with normal or elevated aminotransferase before and after alpha-interferon treatment

Intervirology

Volumn 46, Issue 1, 2003, Pages 35-42

  Montalto, Giuseppe ^a,c   Giannitrapani, Lydia ^a   Soresi, Maurizio ^a   Florena, Ada ^a   Di Martino, Daniela ^a   Franco, Vito ^a   Carroccio, Antonio ^a   Cervello, Melchiorre ^b  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR   (Italy)

^c Ist di Medicina Interna e Geriatria   (Italy)

Author keywords

Interferon; Chronic hepatitis C; Intercellular adhesion molecule 1; Liver disease

Indexed keywords

AMINOTRANSFERASE; INTERCELLULAR ADHESION MOLECULE 1; RECOMBINANT ALPHA2B INTERFERON;

ADULT; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LIVER CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ADULT; ALANINE TRANSAMINASE; ANTIVIRAL AGENTS; ASPARTATE AMINOTRANSFERASES; FEMALE; HEPATITIS C, CHRONIC; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON ALFA-2B; MALE; MIDDLE AGED;

HEPATITIS C VIRUS;

EID: 0037269145     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000068122     Document Type: Article

References (41)

1. Volpes R, Van den Oord JJ, Desmet VJ: Immunohistochemical study of adhesion molecules in liver inflammation. Hepatology 1990;12:59-65.
2. Malizia G, Dino O, Pisa R, Caltagirone M, Giannuoli L, Marco VD, et al: Expression of leukocyte adhesion molecules in the liver of patients with chronic hepatitis B virus infection. Gastroenterology 1991;100:749-755.
3. Adams DH, Hubscher SG, Shaw J, Tothlein R, Neuberger JM: Intercellular adhesion molecule 1 on liver allograft during rejection. Lancet 1989;ii:1122-1125.
4. Burra P, Hubscher SG, Shaw J, Elias E, Adams DH: Is the intercellular adhesion molecule-1/leukocyte function associated antigen 1 pathway of leukocyte adhesion involved in the tissue damage of alcoholic hepatitis? Gut 1992;33:268-271.
5. Horiike N, Onji M, Kumon I, et al: Intercellular adhesion molecule-1 expression on the hepatocyte membrane of patients with chronic hepatitis B and C. Liver 1993;13:10-14.
6. Morita M, Watanabe Y, Akaike T: Inflammatory cytokines up-regulated intercellular adhesion molecule-1 expression on primary cultured mouse hepatocytes and T-lymphocyte adhesion. Hepatology 1994;19:426-431.
7. Mandi Y, Nagy I: Circulating ICAM-1 in alcoholic liver cirrhosis. Int Arch Allergy Immunol 1995;106:302-304.
8. Zohrens G, Armbrust T, Pirzer U, Meyer zum Buschenfelde KH, Ramadori G: Intercellular adhesion molecule-1 concentration in sera of patients with acute and chronic liver disease: Relationship to disease activity and cirrhosis. Hepatology 1993;18:798-802.
9. Simpson KJ, Jones AL, Forbes Howie A, et al: Soluble adhesion molecules and interleukin-2 receptor concentrations in patients with autoimmune chronic hepatitis. Eur J Gastroenterol Hepatol 1995;7:455-460.
10. Nouri-Aria KT, Koskinas J, Tibbs CJ, et al: Serum intercellular adhesion molecule-1 levels in chronic hepatitis C: Association with disease activity and response to interferon alpha. Gut 1995;36:599-603.
11. Bagnasco M, Riccio AM, Sinelli N, et al: Serum intercellular adhesion molecule-1 and long term response to IFN-alpha 2b therapy in chronic hepatitis C. J Interferon Cytokine Res 1998;18:963-966.
12. Sonnante AM, Cozzolongo R, Cuppone R, De Michele G, Manghisi OG, Quaranta M: Soluble intercellular adhesion molecule-1 in sera from patients with chronic hepatitis C undergoing interferon treatment. Arch Virol 1997;142:567-569.
13. Taliani G, Badolato MC, Bozza A, Poliandri G, Duca F, Pasquazzi C, Lecce R, Bruni R, De Bac C: HCV infection of peripheral mononuclear cells and serum levels of soluble ICAM-1 in patients treated with interferon. Arch Virol 1997;142:557-565.
14. Marui A, Fukuda Y, Koyama Y, Nakano I, Urano F, Yamada M, Hayakawa T: Serum levels of soluble intercellular adhesion molecule-1 and soluble vascular cell adhesion molecule-1 in liver disease and their changes by treatment with interferon. J Int Med Res 1996;24:258-265.
15. Lo Iacono O, Garcia-Monzon C, Almasio P, Garcia-Buey L, et al: Soluble adhesion molecules correlate with liver inflammation and fibrosis in chronic hepatitis C treated with interferon-alpha. Aliment Pharmacol Ther 1998;12:1091-1099.
16. Granot E, Shouval D, Ashur Y: Cell adhesion molecules and hyaluronic acid as markers of inflammation, fibrosis and response to antiviral therapy in chronic hepatitis C patients. Mediators Inflamm 2001;10:253-258.
17. Momosaka Y, Yamada S, Harada Y, Mine S, Tsuchiya Y, Okubo H, Eto S: Change of the host immune response during the early phase of interferon therapy correlates with its long-term efficacy for chronic hepatitis C. Hepatol Res 2001;19:131-143.
18. Capra F, De Maria E, Lunardi C, Marchiori L, Mezzelani P, Beri R, Gabrielli GB: Serum level of soluble intercellular adhesion molecule 1 in patients with chronic liver disease related to hepatitis C virus: A prognostic marker for response to interferon treatment. J Infect Dis 2000;181:425-431.
19. Soresi M, Carroccio A, Bonfissuto G, et al: Ultrasound detection of abdominal lymphadenomegaly in subjects with hepatitis C virus and persistently normal transaminases: A predictive index of liver histology severity. J Hepatol 1998;28:544-549.
20. Healey CJ, Chapman RWG, Fleming KA: Liver histology in hepatitis C infection: A comparison between patients with persistently normal or abnormal transaminases. Gut 1995;37:274-278.
21. Shakil AO, Conry-Cantilena C, Alter HJ, et al: Volunteer blood donors with antibody to hepatitis C virus: Clinical, biochemical, virologic and histologic features. Ann Intern Med 1995;123:330-337.
22. Prieto M, Olaso V, Verdu C, et al: Does the healthy hepatitis C virus carrier state really exist? An analysis using polymerase chain reaction. Hepatology 1995;22:413-417.
23. Fukuda Y, Nakano I, Katano Y, Marui A, Hayakawa T: Serum levels of soluble intercellular adhesion molecule-1 and soluble vascular cell adhesion molecule-1 in asymptomatic carriers of hepatitis C virus. J Int Med Res 1998;26:313-318.
24. Montalto G, Zignego AL, Ruggeri MI, Giannini C, Soresi M, Monti M, et al: Serum HCV-RNA and liver histologic findings in patients with long-term normal transaminases. Dig Dis Sci 1997;42:1703-1707.
25. Montalto G, Soresi M, Carroccio A, Campagna P, Vuturo O, Anastasi G, et al: Comparative responses to three different types of interferon-alpha in patients with chronic hepatitis C. Curr Med Res Opin 1998;14:235-241.
26. Knodell R, Ishak KG, Chen BTS, et al: Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981;1:431-435.
27. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ: Classification of chronic hepatitis: Diagnosis, grading, staging. Hepatology 1994;19:1513-1520.
28. Montalto G, Tripi S, Cartabellotta A, Fulco M, Soresi M, Di Gaetano G, et al: Intravenous natural beta-interferon in white patients with chronic hepatitis C who are nonresponders to alpha-interferon. Am J Gastroenterol 1998;93:950-953.
29. Soresi M, Cervello M, Lipani G, Carroccio A, Marasa L, Casto C, Virruso L, Montalto G: Circulating intercellular adhesion molecule-1 in patients with hepatocellular carcinoma. Eur J Gastroenterol Hepatol 1997;9:805-809.
30. Kaplanski G, Farnarier C, Payan MJ, Bongrand P, Durand JM: Increased levels of soluble adhesion molecules in the serum of patients with hepatitis C. Correlation with cytokine concentrations and liver inflammation and fibrosis. Dig Dis Sci 1997;42:2277-2284.
31. Horiike N, Onji M, Kumamoto I, Masumoto T: Soluble intercellular adhesion molecule-1 in serum of chronic hepatitis B and C. J Gastroenterol 1994;24:445-459.
32. Puoti C, Magrini A, Stati T, Rigato P, Montagnese F, Rossi P, Aldegheri L, Resta S: Clinical, histological and virological features of hepatitis C virus carriers with persistently normal or abnormal alanine transaminase levels. Hepatology 1997;26:1393-1398.
33. Czaja AJ, Wolf AM, Baggenstoss AH: Laboratory assessment of severe chronic active liver disease during and after corticosteroid therapy: Correlation of serum transaminase and gamma-globulin levels with histological features. Gastroenterology 1981;80:687-692.
34. Pirisi M, Falletti E, Fabris C, et al: Circulating ICAM-1 concentration in liver disease. Am J Clin Pathol 1994;102:600-604.
35. Martignot-Peignoux M, Marcellin P, Pouteau M, et al: Pre-treatment serum HCV-RNA levels and HCV genotypes are the main independent prognostic factors of sustained response to α-interferon therapy in chronic hepatitis C. Hepatology 1995;22:1050-1056.
36. Garcia-Monzon C, Garcia-Buey L, Garcia-Sanchez A, Pajares JM, Moreno-Otero R: Down-regulation of intercellular adhesion molecule 1 on hepatocytes in viral chronic hepatitis treated with interferon alpha-2b. Gastroenterology 1993;105:462-469.
37. Serfaty L, Chazouillieres O, Pawlotsky JM, Andreani T, Pellet C, Poupon R: Interferon alpha therapy in patients with chronic hepatitis C and persistently normal aminotransferase activity. Gastroenterology 1996;110:291-295.
38. Rossini A, Ravaggi A, Biasi L, Agostinelli B, Bercich L, Gazzola GB, et al: Virological response to interferon treatment in hepatitis C virus carriers with normal aminotransferase levels and chronic hepatitis. Hepatology 1997;26:1012-1017.
39. Sangiovanni A, Morales R, Spinzi G, Rumi MG, Casiraghi A, Cerini R, et al: Interferon alpha treatment of HCV RNA carriers with persistently normal transaminase levels: A pilot randomized controlled study. Hepatology 1998;27:853-856.
40. Lee SS, Sherman M: Pilot study of interferon-α and ribavirin treatment in patients with chronic hepatitis C and normal transaminase values. J Virol Hepat 2001;8:202-205.
41. Hasan F, Asker H, Al-Khalid J, Al-Melhaizeem K, Al Shamali M, Siddique I, Al Nakib B: Interferon-alpha in combination with ribavirin for the treatment of chronic hepatitis C in patients with persistently normal aminotransferase levels. Digestion 2002;65:127-130.