Not all injury-induced muscle proteolysis is due to increased activity of the ubiquitin/proteasome system: Evidence for up-regulation of macrophage-associated lysosomal proteolysis in a model of local trauma

Nutrition Reviews

Volumn 61, Issue 1, 2003, Pages 34-38

  Watford, Malcolm ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Gastrocnemius muscle; Injury; Muscle proteolysis; Skeletal muscle protein; Ubiquitin proteasome system

Indexed keywords

MUSCLE PROTEIN; PROTEASOME; UBIQUITIN; PEPTIDE HYDROLASE;

ANIMAL MODEL; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; LYSOSOME; MACROPHAGE; MUSCLE INJURY; NONHUMAN; PROTEIN DEGRADATION; RAT; SHORT SURVEY; SKELETAL MUSCLE; ANIMAL; ENZYMOLOGY; INJURY; METABOLISM; REVIEW;

ANIMALS; LYSOSOMES; MACROPHAGES; MODELS, ANIMAL; MUSCLE PROTEINS; MUSCLE, SKELETAL; PEPTIDE HYDROLASES; UBIQUITIN;

EID: 0037269087     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1301/nr.2003.janr.34-38     Document Type: Short Survey

References (23)

1. Institute of Medicine. Dietary reference intakes for energy, carbohydrate, fiber, fatty acids, cholesterol, protein and amino acids. Washington, DC: National Academy Press; 2002.
2. McNurlan MA, Garlick PJ. Protein synthesis and degradation. In: Stipanuk MH, ed. Biochemical and Physiological Aspects of Human Nutrition. Philadelphia, PA: W.B. Saunders Company; 2000:211-232.
3. Goldstein SA, Elwyn DH. The effects of injury and sepsis on fuel utilization. Annu Rev Nutr. 1989;9:445-473.
4. Lecker SH, Solomon V, Mitch WE, Goldberg AL. Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states. J Nutr. 1999;12:227S-237S.
5. Jagoe RT, Goldberg AL. What do we really know about the ubiquitin proteasome pathway in muscle atrophy? Curr Opin Clin Nutr Metab Care. 2001;4:183-190.
6. Fang C-H, Li B-G, Fischer DR, et al. Burn injury upregulates the activity and gene expression of the 20S proteasome in rat skeletal muscle. Clin Sci. 2000;99:181-187.
7. Hasselgren P-O, Wray C, Mammen J. Molecular regulation of muscle cachexia: it may be more than the proteasome. Arch Biochem Biophys. 2002;290:1-10.
8. Larbaud D, Balage M, Taillandier D, Combaret L, Grizard J, Attaix D. Differential regulation of the lysosomal, Ca2+ dependent and ubiquitin/proteasome dependent proteolytic pathways in fast-twitch and slow-twitch rat muscle following hyperinsulinaemia. Clin Sci. 2001;101:551-558.
9. Farges M-C, Balcerzak D, Fisher BD, et al. Increased muscle proteolysis after local trauma mainly reflects macrophage associated lysosomal proteolysis. Am J Physiol Endocrinol Metab. 2002;282:E326-E335.
10. Carpenter KJ. Protein and energy. Cambridge, UK: Cambridge University Press; 1994.
11. Folin O. A theory of protein metabolism. Am J Physiol. 1905;13:117-138.
12. Schoenheimer R. The dynamic state of body constituents. Cambridge, MA: Harvard University Press; 1941.
13. Dice JF. Lysosomal degradation of proteins. Encyclopedia of Life Sciences. Nature Publishing Group; 2001. Available at: http://www.els.net/els/els/els/index.html.
14. Pillay CS, Elliott E, Dennison C. Endolysomal proteolysis and its regulation. Biochem J. 2002;363:417-429.
15. Hershko A. The ubiquitin pathway for protein degradation. Trends Biochem Sci. 1991;16:265-268.
16. Lam YA, Pickart CM. Ubiquitin pathway. Encyclopedia of Life Sciences. Nature Publishing Group; 2001. Available at: http://www.els.net/els/els/els/index.html.
17. Finley D. Protease complexes. Encyclopedia of Life Sciences. Nature Publishing Group; 2001. Available at: http:/www.els.net/els/els/els/index.html.
18. Kisselev AF, Goldberg AL. Proteasome inhibitors: from research tools to drug candidates. Chem Biol. 2001;8:739-758.
19. Maltin CA, Delday MI, Baillie AGS, Grubb DA, Garlick PJ. Fiber-type composition of nine rat muscles. I. Changes during the first year of life. Am J Physiol. 1989;257:E823-E827.
20. Fawcett J, Hamel FG, Duckworth WC. Characterization of the inhibition of protein degradation by insulin in L6 cells. Arch Biochem Biophys. 2001;385:357-363.
21. Mordier S, Deval C, Bechet D, Tassa A, Ferrara M. Leucine limitation induces autophagy and activation of lysosome dependent proteolysis in C2C12 myotubules through a mammalian target of rapamycin independent signaling pathway. J Biol Chem. 2000;275:29900-29906.
22. Solomon V, Madihally S, Yarmush M, Toner M. Insulin suppresses the increased activities of lysosomal cathepsins and ubiquitin conjugation system in burn-injured rats. J Surg Res. 2000;93:120-126.
23. Mansoor O, Beaufrere B, Boirie Y, et al. Increased mRNA levels for components of the lysosomal, Ca2+ activated and ATP ubiquitin dependent proteolytic pathways in skeletal muscle from head trauma patients. Proc Natl Acad Sci U S A. 1996;93:2714-2718.