The Inhalation Manager: A new computer-based device to assess inhalation technique and drug delivery to the patient

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung

Volumn 16, Issue 1, 2003, Pages 21-29

  Kamin, Wolfgang E S ^a   Genz, Tilman ^b   Roeder, Sascha ^c   Scheuch, Gerhard ^c   Cloes, Rolf ^c   Juenemann, Ralf ^c   Trammer, Thomas ^c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b InAMed GmbH ^*

^c 3M Deutschland GmbH   (Germany)

Author keywords

Asthma management; Inhalation technique; Patient education

Indexed keywords

BECLOMETASONE DIPROPIONATE; BUDESONIDE; FLUTICASONE PROPIONATE; GLUCOCORTICOID;

ADULT; AGED; ARTICLE; ASTHMA; BREATHING; COMPUTER PROGRAM; CONTROLLED STUDY; DEVICE; DRUG DELIVERY SYSTEM; FEMALE; HUMAN; INHALER; INSPIRATORY CAPACITY; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; NEBULIZATION; PARTICLE SIZE; PATIENT EDUCATION; PNEUMOTACHYGRAPHY; PULMONOLOGY;

ADOLESCENT; ADULT; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEBULIZERS AND VAPORIZERS; PARTICLE SIZE;

EID: 0037267543     PISSN: 08942684     EISSN: None     Source Type: Journal    
DOI: 10.1089/089426803764928329     Document Type: Article

References (34)

1. Dhand, R. 2000. Aerosol therapy for asthma. Curr. Opin. Pulm. Med. 6:59-70.
2. Cochrane, M.G., M.V. Bala, K.E. Downs, et al. 2000. Inhaled corticosteroids for asthma therapy - patient compliance, devices, and inhalation technique. Chest 117:542-550.
3. Lenney, J., J.A. Innes, and G.K. Crompton. 2000. Inappropriate inhaler use: assessment of use and patient preference of seven inhalation devices. Respir. Med. 94:496-500.
4. Duerden, M., and D. Price. 2001. Training issues in the use of inhalers. Dis. Manage. Health Outcomes 9:75-87.
5. Dekhuijzen, P.N.R. 2001. Inhalation therapy in asthma and COPD: who, where and how? Eur. Pharmaceut. Rev. 74-78.
6. Roche, N., and G.J. Huchon. 2000. Rationale for the choice of aerosol delivery system. J. Aerosol Med. 13:393-404.
7. Fong, P.M., and D.E. Sinclair. 1993. Inhalation devices for asthma - choosing the right one could make all the difference. Can. Fam. Physician 39:2377-2382.
8. Pedersen, S. 1996. Inhalers and nebulizers: which to choose and why. Respir. Med. 90:69-77.
9. Ross, D.L., and R.K. Schultz. 1996. Effect of inhalation flow rate on the dosing characteristics of dry powder inhaler (DPI) and metered dose inhaler (MDI) products. J. Aerosol Med. 9:215-226.
10. Smith, K.J., H.-K. Chan, and K.F. Brown. 1998. Influence of flow rate on aerosol particle size distributions from pressurized and breath-actuated inhalers. J. Aerosol Med. 11:231-245.
11. Kamin, W.E.S., T. Genz, S. Roeder, et al. 2002. Mass output and particle size distribution of glucocorticosteroids emitted from different inhalation devices depending on various inspiratory parameters. J. Aerosol Med. 15:65-73.
12. Everard, M.L., S.G. Devadason, and P.N. LeSouéf. 1997. Flow early in the inspiratory manoeuvre affects the aerosol particle size distribution from a Turbohaler. Respir. Med. 91:624-628.
13. Olsson, B., and L. Asking. 1994. Critical aspects of the function of inspiratory flow driven inhalers. J. Aerosol Med. 7(Suppl. 1):S43-S47.
14. Srichana, T., G.P. Martin, and C. Marriott. 1998. Dry powder inhalers: the influence of device resistance and powder formulation on drug and lactose deposition in vitro. Eur. J. Pharmaceut. Sci. 7:73-80.
15. Tarsin, W., K. Assi, O.J. Corrado, et al. 2000. Measurement of patient inhalation rates for different dry powder inhalers (DPIs) using the In-Check Dial. Thorax 55(Suppl. 3):A63.
16. Nsour, W.M., A. Alldred, O.J. Corrado, et al. 2000. The In-Check Meter to identify inhalation rates of patients when using a dry powder device. J. Aerosol Med. 13:61.
17. Dhand, R., and J. Fink. 1999. Dry powder inhalers. Respir. Care 44:940-951.
18. Baum, E.A. 1989. Design, development and testing of a new breath actuated inhaler. In Inspiration: Development in Inhalation therapy. Medicine Publishing Foundation Symposium Series 26. Oxford, The Medicine Group, 20-30.
19. Fuller, R. 1995. The Diskus™: a new multi-dose powder-device - efficacy and comparison with Turbohaler™. J. Aerosol. Med. 8(Suppl. 2):S11-S17.
20. Malton, A., B.S. Sumby, and Y. Dandiker. 1996. A comparison of in vitro drug delivery from salbutamol Diskus and terbutaline Turbohaler inhalers. J. Pharm. Med. 6:35-48.
21. Martonen, T., and Y. Yang. 1996. Deposition mechanics of pharmaceutical particles in human airways. In A.J. Hickey, ed. Inhalation Aerosols: Physical and Biological Basis for Therapy. New York, 1:3-27.
22. Cross, S. 2001. Asthma inhalation delivery systems: the patient's viewpoint. J. Aerosol Med. 14(Suppl. 1):S3-S7.
23. Wilson, A.M., O.J. Dempsey, W.J.R. Coutie, et al. 1999. Importance of drug-device interaction in determining systemic effects of inhaled corticosteroids. Lancet 353:2128.
24. Van Beerendonk, I., Mesters, I., Mudde, A.N., et al. 1998. Assessment of inhalation technique in outpatients with asthma or chronic obstructive pulmonary disease using a metered-dose inhaler or dry powder device. J. Asthma 35:273-279.
25. Van der Palen, J., Klein, J.J., Kerkhoff, A.H.M., et al. 1995. Evaluation of the effectiveness of four different inhalers in patients with chronic obstructive pulmonary disease. Thorax 50:1183-1187.
26. Van der Palen, J., Klein, J.J., and A.M. Schildkamp. 1998. Comparison of a new multidose powder inhaler (Diskus®/Accuhaler®) and the Turbuhaler® regarding preference and ease of use. J. Asthma 35:147-152.
27. Branco Ferreira, M., Santos, A., Clode, M.H., et al. 1999. Turbutest™ in the training of asthmatic Turbuhaler™ users. Allergy 54:375-379.
28. Johnson, S., Miles, J.F., Weir, D.C., et al. 1996. Turbohaler: objective assessment of patient-generated flow. Thorax 51(Suppl. 3):A75.
29. Dewar, M.H., Jamieson, A., McLean, A., et al. 1999. Peak inspiratory flow through the Turbuhaler® in chronic obstructive airway disease. Respir. Med. 93:342-344.
30. Engel, T., Heinig, J.H., Madsen, F., et al. 1990. Peak inspiratory flow and inspiratory vital capacity of patients with asthma measured with and without a new dry-powder inhaler device (Turbuhaler®). Eur. Respir. J. 3:1037-1041.
31. Hawksworth, G.M., James, L., and H. Chrystyn. 2000. Characterization of the inspiratory manoeuvre when asthmatics inhale through a Turbohaler pre- and postcounselling in a community pharmacy. Respir. Med. 94:501-504.
32. Finlay, W.H., and M.G. Gehmlich. 2000. Inertial size of aerosol inhaled from two dry powder inhalers with realistic breath patterns versus constant flow rates. Int. J. Pharmaceutics 210:83-95.
33. Newman, S.P. 1998. How well do in vitro particle size measurements predict drug delivery in vivo. J. Aerosol Med. 11(Suppl. 1):S997-S104.
34. Giraud, V., and N. Roche. 2002. Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability. Eur. Respir. J. 19:246-251.