A prospective, randomized, controlled trial of benzodiazepines and nitroglycerine or nitroglycerine alone in the treatment of cocaine-associated acute coronary syndromes

American Journal of Emergency Medicine

Volumn 21, Issue 1, 2003, Pages 39-42

  Honderick, Tim ^a   Williams, David ^a   Seaberg, David ^a   Wears, Robert ^a  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

Benzodiazepine; Chest pain; Cocaine

Indexed keywords

BENZODIAZEPINE DERIVATIVE; COCAINE; GLYCERYL TRINITRATE; LORAZEPAM;

ACUTE HEART INFARCTION; ADULT; ANALGESIA; ARTICLE; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; COCAINE DEPENDENCE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEART MUSCLE ISCHEMIA; HOSPITALIZATION; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; THORAX PAIN;

EID: 0037262703     PISSN: 07356757     EISSN: None     Source Type: Journal    
DOI: 10.1053/ajem.2003.50010     Document Type: Article

References (24)

1. Hollander JE: The management of cocaine induced myocardial ischemia. N Engl J Med 1995;333(19):1267-1272
2. Hollander JE, Hoffman RS, Gennis P, et al: Prospective multicenter evaluation of cocaine associated chest pain. Cocaine associated chest pain (COCHPA) study group. Acad Emerg Med. 1994;1:330-339
3. Tokarski GF, Paganussi P, Urbanski R, et al: An evaluation of cocaine-induced chest pain. Ann Emerg Med 1190;19:1088-1082
4. Lange RA, Cigarroa RG, Yancy CW, et al: Cocaine induced coronary vasoconstriction. N Engl J Med 1989;321:1557-1562
5. Moliterno DJ, Willard JE, Lange RA, et al: Coronary-artery vasoconstriction induced by cocaine, cigarette smoking, or both. N Engl J Med 1994;330:454-459
6. Tonga G, Tempesta E, Tonga AR, et al: Platelet responsiveness and biosynthesis of thromboxane and prostacyclin in response to in vitro cocaine treatment. Hemostasis 1985;15:100-107
7. Schnetzer GW: Platelets and thrombogenesis - current concepts. Am Heart J 1972;83:552-564
8. Goldfrank LR, Hoffman RS: The cardiovascular effects of cocaine. Ann Emerg Med 1991;20:165-175
9. Lange RA, Cigarroa RG, Flores ED, et al: Potentiation of cocaine-induced coronary vasoconstriction by beta-adrenergic blockade. Ann Intern Med 1990;112:897-903
10. Second American Heart Association International Evidence Evaluation Conference; Part 6: Advanced Cardiovascular Life Support; Section 1: Introduction to ACLS 2000: Overview of Recommended Changes in ACLS From the Guidelines 2000 Conference. Circulation 2000;102(suppl 1):186-189
11. Shih RD, Hollander JE: Management of cocaine associated chest pain. Hosp Phys 1996;45:11-22
12. Guinn MM, Bedford JA, Wilson MC: Antagonism of intravenous cocaine lethality in non-human primates. Clin Toxicol 1980;16:499-508
13. Catravas JD, Waters IW: Acute cocaine intoxication in the conscious dog: studies on the mechanism of lethality. J Pharmacol Exp Ther 1981;217:350-356
14. Catravas JD, Waters IW, Waiz MA, et al: Acute cocaine intoxication in the conscious dog: Pathophysiologic profile of acute lethality. Arch Int Pharmacodyn Ther 1978;235:328-340
15. Baumann BM, Perrone J, Hornig SE, et al: Randomized, Double-blind, placebo-controlled trial of diazepam, nitroglycerine, or both for treatment of patients with potential cocaine-associated acute coronary syndromes. Acad Emerg Med 2000;7:878-886
16. Rezkalla SH, Mazza JJ, Kloner RA, et al: The effects of cocaine on human platelets in healthy subjects. Am J Cardiol 1993;72:243-246
17. Ferraz MB, Quaresma MR, Aquino LR, et al: Reliability of pain scales in the assessment of literate and illiterate patients with rheumatoid arthritis. J Rheumatol 1990;17:1022-1024
18. Downie WW, Leatham PA, Rhind VM, et al: Studies with pain rating scales. Ann Rheum Dis 1978;37:378-381
19. Geller NL, Pocock SJ: Interim analyses in randomized clinical trials: Ramifications and guidelines for practitioners. Biometrics 1987;43:213-223
20. Lange RA, Cigarroa RG, Flores ED, et al: Potentiation of cocaine-induced coronary vasoconstriction by beta-adrenergic blockade. Ann Intern Med 1990;112:897-903
21. Seubert CN, Morey TE, Martynyuk AE, et al: Midazolam selectively potentiates the A2A- but not A1-receptor-mediated effects of adenosine. Anesthesiology 2000;92:567-577
22. Hollander JE, Lozano M, Goldtein E, et al: Variations in the electrocardiograms of young adults: Are revised criteria for thrombolysis needed? Acad Emerg Med 1994;1:94-102
23. Hollander JE, Burstein JL, Hoffman RS, et al: Cocaine associated myocardial infarction study group. Chest 1995;107:1237-1241
24. Hollander JE, Hoffman RS, Gennis P, et al: Nitroglycerin in the treatment of cocaine associated chest pain - clinical safety and efficacy. J Toxicol Clin Toxicol 1994;32:243-256