Impact of AUC/MIC ratios on the pharmacodynamics of the des-F(6) quinolone garenoxacin (BMS-284756) is similar to other fluoroquinolones [14]

Journal of Antimicrobial Chemotherapy

Volumn 51, Issue 1, 2003, Pages 199-202

  Lister, Philip D ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GARENOXACIN; LEVOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; AREA UNDER THE CURVE; CONTROLLED STUDY; DRUG EFFICACY; ERADICATION THERAPY; LETTER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; FLUOROQUINOLONES; HUMANS; INDOLES; MICROBIAL SENSITIVITY TESTS; QUINOLONES; STREPTOCOCCUS PNEUMONIAE;

EID: 0037259153     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg017     Document Type: Letter

References (6)

1. Fung-Tomc, J. C., Minassian, B., Kolek, B., Huczko, E., Aleksunes, L., Stickle, T. et al. (2000). Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756. Antimicrobial Agents and Chemotherapy 44, 3351-6.
2. Wu, P., Lawrence, L. E., Denbleyker, K. L. & Barrett, J. F. (2001). Mechanism of action of the des-F(6) quinolone BMS-284756 measured by supercoiling inhibition and cleavable complex assays. Antimicrobial Agents and Chemotherapy 45, 3660-2.
3. Lister, P. D. & Sanders, C. C. (2001). Pharmacodynamics of moxifloxacin, levofloxacin, and sparfloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model. Journal of Antimicrobial Chemotherapy 47, 811-8.
4. Lister, P. D. (2002). Pharmacodynamics of gatifloxacin against Streptococcus pneumoniae: impact of AUC:MIC ratios on eradication from an in vitro pharmacodynamic model. Antimicrobial Agents and Chemotherapy 46, 69-74.
5. Ambrose, P. G., Grasela, D. M., Grasela, T. H., Passarell, J., Mayer, H. B. & Pierce, P. F. (2001). Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections. Antimicrobial Agents and Chemotherapy 45, 2793-7.
6. Drusano, G. L., Johnson, D. E., Rosen, M. & Standiford, H. C. (1999). Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas aeruginosa sepsis. Antimicrobial Agents and Chemotherapy 37, 483-90.