Synthesis, characterization, and biological evaluation of technetium(III) complexes with tridentate/bidentate S,E,S/P,S coordination (E = O, N(CH3), S): A novel approach to robust technetium chelates suitable for linking the metal to biomolecules

Bioconjugate Chemistry

Volumn 14, Issue 1, 2003, Pages 136-143

  Pietzsch, Hans Juergen ^a   Seifert, Sepp ^a   Syhre, Rosemarie ^a   Tisato, Francesco ^b   Refosco, Fiorenzo ^b   Leibnitz, Peter ^c   Spies, Hartmut ^a  

^a INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

^b CNR   (Italy)

^c BAM FEDERAL INSTITUTE FOR MATERIALS RESEARCH AND TESTING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; LIGANDS; MOLECULAR BIOLOGY; RATS; SYNTHESIS (CHEMICAL); TECHNETIUM; TECHNETIUM COMPOUNDS;

BIODISTRIBUTIONS; BIOLOGICAL EVALUATION; COORDINATED COMPLEXES; COORDINATION GEOMETRY; MIXED-LIGANDS; P-S LIGAND; SYNTHESIS EVALUATION; TECHNETIUM-; TRIGONAL BIPYRAMIDAL COORDINATIONS; TWO-STEP REDUCTION;

CHELATION;

ALKYL GROUP; CHELATE; CHLORINE; COORDINATION COMPOUND; GLUTATHIONE; LIGAND; METAL; PHOSPHINE DERIVATIVE; PHOSPHORUS; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; SULFUR; TECHNETIUM 99M; TECHNETIUM COMPLEX; THIOL DERIVATIVE; TRIPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CROSS LINKING; DISSOLUTION; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; GEOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; LUNG; MALE; NONHUMAN; RADIOMETRY; RAT; REDUCTION; SOLID; SUBSTITUTION REACTION; ULTRAVIOLET SPECTROSCOPY;

ANIMALIA;

EID: 0037257744     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc025575v     Document Type: Article

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