Comparison of exhaled and nasal nitric oxide and exhaled carbon monoxide levels in bronchiectatic patients with and without primary ciliary dyskinesia

Thorax

Volumn 58, Issue 1, 2003, Pages 68-72

  Horvath I ^b   Loukides, S ^a   Wodehouse, T ^a   Csiszer E ^b   Cole, P J ^a   Kharitonov, S A ^a   Barnes, P J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b NATIONAL KORANYI INSTITUTE OF PULMONOLOGY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; NITRIC OXIDE;

ADULT; ALLERGIC REACTION; ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL COLONIZATION; BRONCHIECTASIS; CELL FUNCTION; CILIARY DYSKINESIA; FEMALE; HUMAN; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MAJOR CLINICAL STUDY; MALE; MUCOCILIARY CLEARANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK ASSESSMENT; SCREENING TEST;

ADULT; BREATH TESTS; BRONCHIECTASIS; CARBON MONOXIDE; CILIARY MOTILITY DISORDERS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MOUTH BREATHING; NITRIC OXIDE; NOSE; SENSITIVITY AND SPECIFICITY; VITAL CAPACITY;

EID: 0037256640     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.58.1.68     Document Type: Article

References (28)

1. Greenstone M, Rutman A, Dewar A, et al. Primary ciliary dyskinesia: cytological and clinical features. Q J Med 1988;253:405-30.
2. Pedersen H, Mygind N. Absence of axonemal arms in nasal mucosa cilia in Kartagener's syndrome. Nature 1976;262:494-5.
3. Kharitonov SA, Yates D, Robbins RA, et al. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994;343:146-7.
4. Horváth I, Donnelly LE, Kiss A, et al. Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker oxidative stress. Thorax 1998;53:668-72.
5. Zayasu K, Sekizawa K, Okinaga S, et al. Increased carbon monoxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1997;156:1140-3.
6. Kharitonov SA, Barnes PJ. Exhaled markers of pulmonary disease. Am J Respir Crit Care Med 2001;163:1693-722.
7. Horváth I, Kiss A, Barnes PJ. Relation of exhaled carbon monoxide to other markers of asthma in non-smoking patients. Am J Respir Crit Care Med 1998;157:A610.
8. Kharitonov SA, Wells AU, O'Connor BJ, et al. Elevated levels of exhaled nitric oxide in bronchiectasis. Am J Respir Crit Care Med 1995;151:1889-93.
9. Horváth I, Loukides S, Wodehouse T, et al. Increased levels of exhaled carbon monoxide in bronciectasis: a new marker of oxidative stress. Thorax 1998;53:867-70.
10. Loukides S, Kharitonov SA, Wodehouse T, et al. L-arginine increases nasal nitric oxide and improves mucociliary function in primary ciliary dyskinesia. Lancet 1998;352:371-2.
11. Karadag B, James AJ, Gultekin E, et al. Nasal and lower airway level of nitric oxide in children with primary ciliary dyskinesia. Eur Respir J 1999;13:1402-5.
12. Lundberg JON, Weitzberg E, Nordvall SL, et al. Primary nasal origin of exhaled nitric oxide and absence in Kartagener's syndrome. Eur Respir J 1994;7:1501-4.
13. Thomas SR, Kharitonov SA, Scott SF, et al. Nasal and exhaled nitric oxide is reduced in adult patients with cystic fibrosis and does not correlate with cystic fibrosis genotype. Chest 2000;117:1085-9.
14. Rayner CF, Rutman A, Dewar A, et al. Ciliary disorientation in patients with chronic upper respiratory tract inflammation. Am J Respir Crit Care Med 1995;151:800-4.
15. Leischow SJ, Merikle EP, Cook G, et al. An evaluation of NicCheck I: a dipstick method for analyzing nicotine and its metabolites. Addict Behav 1999;1:145-8.
16. Ekroos H, Tuominen J, Sovijarvi AR. Exhaled nitric oxide and its long-term variation in healthy non-smoking subjects. Clin Physiol 2000;20:434-9.
17. Cunnington AJ, Normbrey P. Breath analysis to detect recent exposure to carbon monoxide. Postgrad Med 2002;78:233-8.
18. Horvath I, Donnelly LE, Kiss A, et al. Combined use of exhaled hydrogen peroxide and nitric oxide in monitoring asthma. Am J Respir Crit Care Med 1998;158:1042-6.
19. Keatings VM, Jatakanon A, Worsdell MY, et al. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med 1997;155:542-8.
20. Kharitonov SA, Rajakulasigam K, O'Connor B, et al. Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids. J Allergy Clin Immunol 1997;99:58-64.
21. Ho JP, Innes JA, Greening AP. Exhaled nitric oxide is not elevated in the inflammatory airway diseases of cystic fibrosis and bronchiectasis. Eur Respir J 1998;12:1290-4.
22. Arnal JF, Flores P, Rami J, et al. Nasal nitric oxide concentration in paranasal sinus inflammatory diseases. Eur Respir J 1999;13:307-12.
23. Lindberg S, Cervin A, Runer T. Nitric oxide (NO) production in the upper airways is decreased in chronic sinusitis. Acta Otolaryngol 1997;117:113-7.
24. Eller J, Lapa-e-Silva JR, Poulter LW, et al. Cells and cytokines in chronic bronchial infection. Ann NY Acad Sci 1994;725:331-45.
25. Choi AMK, Alam J. Heme oxygenase-1: Function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am J Respir Cell Mol Biol 1996;15:9-19.
26. Loukides S, Horváth I, Wodehouse T, et al. Elevated levels of expired breath hydrogen peroxide in bronchiectasis. Am J Respir Crit Care Med 1998;158:991-4.
27. Donnelly LE, Barnes PJ. Expression of heme oxygenase in human airway epithelial cells. Am J Respir Cell Mol Biol 2001;24:295-303.
28. Paredi P, Shah PL, Montuschi P, et al. Increased carbon monoxide in exhaled air of patients with cystic fibrosis. Thorax 1999;54:917-20.