Distributed versus compartment models for PET receptor studies

IEEE Transactions on Medical Imaging

Volumn 22, Issue 1, 2003, Pages 11-21

  Muzic Jr , Raymond F ^a,b   Saidel, Gerald M ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b Case Western Reserve University   (United States)

Author keywords

Compartment model; Distributed model; Positron emission tomography; Receptor experiment

Indexed keywords

COMPUTER SIMULATION; ESTIMATION; IMAGE ANALYSIS; MATHEMATICAL MODELS; NUCLEAR MEDICINE; POSITRON EMISSION TOMOGRAPHY;

COMPARTMENT MODEL; DISTRIBUTED MODEL;

MEDICAL IMAGING;

CELL SURFACE RECEPTOR; DIAGNOSTIC AGENT; LIGAND; RADIOPHARMACEUTICAL AGENT;

ARTICLE; BIOLOGICAL MODEL; CHEMICAL MODEL; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER SIMULATION; EVALUATION; HEART; HEART MUSCLE; HUMAN; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; PHYSIOLOGY; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

COMPUTER SIMULATION; HEART; HUMANS; LIGANDS; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; MODELS, CARDIOVASCULAR; MODELS, CHEMICAL; MYOCARDIUM; RADIOPHARMACEUTICALS; RECEPTORS, CELL SURFACE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0037255984     PISSN: 02780062     EISSN: None     Source Type: Journal    
DOI: 10.1109/TMI.2002.806576     Document Type: Article

References (33)

1. K. Zierler, "A critique of compartmental analysis," Annu. Rev. Biophys. Bioeng., vol. 10.531-62, pp. 531-562, 1981.
2. R. F. Muzic, Jr, A. D. Nelson, G. M. Saidel, and F. Miraldi, "Optimal experiment design for PET quantification of receptor concentration," IEEE Trans. Med. Imag., vol. 15, pp. 2-12, Feb. 1996.
3. R. F. Muzic, Jr., G. M. Saidel, N. Zhu, A. D. Nelson, L. Zheng, and M. S. Berridge, "Iterative optimal design of PET experiments for estimating β-adrenergic receptor concentration," Med. Biol. Eng. Comput., vol. 38, no. 6, pp. 593-602, Nov. 2000.
4. J. R. Votaw, R. M. Kessler, and T. de Paulis, "Failure of the three compartment model to describe the pharmacokinetics in brain of a high affinity substituted benzamide," Synapse, vol. 15, no. 3, pp. 177-190, Nov. 1993.
5. B. R. Zeeberg, R. C Reid, K. A. Murphy, and R. C. Reba, "Theoretical effects of radioligand diffusional gradients and microscopic neuroreceptor distribution in in vivo kinetic studies," Bull. Math. Biol., vol. 50, no. 5, pp. 423-444, 1988.
6. J. Delforge, A. Syrota, and B. Bendriem, "Reaction volume concept [letter; comment]," J. Nucl. Med., vol. 38, no. 2, pp. 341-342, Feb. 1997.
7. J. Delforge, A. Syrota, and B. M. Mazoyer, "Experimental design optimization: Theory and application to estimation of receptor model parameters using dynamic positron emission tomography," Phys. Med. Biol., vol. 34, no. 4, pp. 419-435, Apr. 1989.
8. R. F. Muzic, Jr. A. D. Nelson, G. M. Saidel, and F. Miraldi, "Optimal experimental design for receptor modeling," Ann. Biomed. Eng., vol. 22, no. Suppl 1, p. 43, 1994.
9. E. D. Morris, N. M. Alpert, and A. J. Fischman, "Comparison of two compartmental models for describing receptor ligand kinetics and receptor availability in multiple injection PET studies," J. Cereb. Blood Flow Metab., vol. 16, no. 5, pp. 841-853, Sept. 1996.
10. R. F. Muzic, Jr. and S. Cornelius, "COMKAT: compartment model kinetic analysis tool," J. Nucl. Med., vol. 42, no. 4, pp. 636-645, Apr. 2001.
11. J. B. Bassingthwaighte, B. Winkler, and R. B. King, "Potassium and thallium uptake in dog myocardium," J. Nucl. Med., vol. 38, no. 2, pp. 264-274, Feb. 1997.
12. D. A. Beard and J. B. Bassingthwaighte, "Advection and diffusion of substances in biological tissues with complex vascular networks," Ann. Biomed. Eng., vol. 28, no. 3, pp. 253-268, 2000.
13. W. E. Schiesser and C. A. Silebi, Computational Transport Phenomena. Cambridge, U.K.: Cambridge Univ.y Press, 1997.
14. L. F. Shampine and M. W. Reichelt, "The MATLAB ODE suite," SIAM J. Scientif. Computing, vol. 18, no. 1, pp. 1-22, 1997.
15. J. Delforge, A. Syrota, and B. M. Mazoyer, "Identifiability analysis and parameter identification of an in vivo ligand-receptor model from PET data," IEEE Trans. Biomed. Eng., vol. 37, pp. 653-661, July 1990.
16. T. Coleman, M. Branch, and A. Grace, Optimization Toolbox for Use with Matlab, User's Guide. South Natick, MA: The Mathworks, Inc., 1999.
17. K. B. Larson, J. Markham, and M. E. Raichle, "Tracer-kinetic models for measuring cerebral blood flow using externally detected radiotracers," J. Cereb. Blood Flow Metab., vol. 7, no. 4, pp. 443-463, Aug. 1987.
18. Y. Sawada, Y. Sugiyama, T. Iga, and M. Hanano, "Tracer disposition kinetics in the determination of local cerebral blood flow by a venous equilibrium model, tube model, and distributed model," J. Cereb. Blood Flow Metab., vol. 7, no. 4, pp. 433-442, Aug. 1987.
19. R. P. Quarles, M. A. Mintun, K. B. Larson, J. Markham, A. M. MacLeod, and M. E. Raichle, "Measurement of regional cerebral blood flow with positron emission tomography: A comparison of [15O] water to [11C] butanol with distributed-parameter and compartmental models," J. Cereb. Blood Flow Metab., vol. 13, no. 5, pp. 733-747, Sept. 1993.
20. K. A. Bergstrom, M. Yu, J. T. Kuikka, K. K. Akerman, J. Hiltunen, J. Lehtonen, C. Halldin, and J. Tiihonen, "Metabolism of [123I] epidepride may affect brain dopamine D2 receptor imaging with single-photon emission tomography," Eur. J. Nucl. Med., vol. 27, no. 2, pp. 206-208, Feb. 2000.
21. A. N. Gifford, S. J. Gatley, and C. R. Ashby, Jr, "Endogenously released dopamine inhibits the binding of dopaminergic PET and SPECT ligands in superfused rat striatal slices," Synapse, vol. 22, no. 3, pp. 232-238, Mar. 1996.
22. B. R. Zeeberg, R. E. Gibson, and R. C. Reba, "Elevated D2 dopamine receptors in drug-naive schizophrenics [letter]," Science, pt. 1, vol. 239, no. 4841, pp. 789-791, Feb. 1988.
23. J. B. Bassingthwaighte, C. Y. Wang, and I. S. Chan, "Blood-tissue exchange via transport and transformation by capillary endothelial cells," Circ. Res., vol. 65, no. 4, pp. 997-1020, Oct. 1989.
24. J. B. Bassingthwaighte, I. S. Chan, and C. Y. Wang, "Computationally efficient algorithms for convection-permeation-diffusion models for blood-tissue exchange," Ann. Biomed. Eng., vol. 20, no. 6, pp. 687-725, 1992.
25. M. A. Mintun, M. E. Raichle, M. R. Kilbourn, G. F. Wooten, and M. J. Welch, "A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography," Ann. Neurol., vol. 15, no. 3, pp. 217-227, Mar. 1984.
26. S. C. Huang, M. E. Phelps, E. J. Hoffman, K. Sideris, C. J. Selin, and D. E. Kuhl, "Noninvasive determination of local cerebral metabolic rate of glucose in man," Amer. J. Physiol., vol. 238, no. 1, pp. E69-E82, Jan. 1980.
27. M. E. Phelps, S. C. Huang, E. J. Hoffman, C. Selin, L. Sokoloff, and D. E. Kuhl, "Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: Validation of method," Ann. Neurol., vol. 6, no. 5, pp. 371-388, Nov. 1979.
28. M. Reivich, D. Kuhl, A. Wolf, J. Greenberg, M. Phelps, T. Ido, V. Casella, J. Fowler, B. Gallagher, E. Hoffman, A. Alavi, and L. Sokoloff, "Measurement of local cerebral glucose metabolism in man with 18F-2-fluoro-2-deoxy-d-glucose," Acta Neurol. Scand. Suppl., vol. 64, no. 190-1, pp. 190-191, 1977.
29. 14C]-2-deoxy-d-glucose method for measuring local cerebral glucose utilization. Mathematical analysis and determination of the "lumped" constants," Neurosci. Res. Program. Bull., vol. 14, no. 4, pp. 466-468, Sept. 1976.
30. 14C] deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthesized albino rat," J. Neurochem., vol. 28, no. 5, pp. 897-916, May 1977.
31. 15O. II. Implementation and validation," J. Nucl. Med., vol. 24, no. 9, pp. 790-798, Sept. 1983.
32. 15O. I. Theory and error analysis," J. Nucl. Med., vol. 24, no. 9, pp. 782-789, Sept. 1983.
33. S. Middleman, Transport Phenomena in the Cardiovascular System. New York: Wiley, 1972.