Homocysteine alters monocyte-endothelial interaction in vitro

Chinese Medical Journal

Volumn 116, Issue 1, 2003, Pages 34-38

  Guo, Xuewei ^a   Peter, Dudman Nicholas ^b  

^a GANSU PROVINCIAL HOSPITAL   (China)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Endothelium; Homocysteine; Monocytes

Indexed keywords

CATALASE; CD11B ANTIGEN; CD14 ANTIGEN; CD18 ANTIGEN; HOMOCYSTEINE; HYDROGEN PEROXIDE; MONOCLONAL ANTIBODY;

ANALYTIC METHOD; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM LESION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MONOCYTE; UPREGULATION;

ARTERIOSCLEROSIS; CELL ADHESION; CELL COMMUNICATION; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HOMOCYSTEINE; HUMANS; MONOCYTES;

EID: 0037253667     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Roth J, Goebeler M, Ludwig S, et al. Homocysteine inhibits tumor necrosis factor-induced activation of endothelium via modulation of nuclear factor-kappa B activity. Biochim Biophys Acta 2001;22;1540:154-165.
2. Wang J, Dudman NPB, Wilken DEL. Effects of homocysteine and related compounds on prostacyclin production by cultured human vascular endothelial cells. Thromb Haemost 1993;70:1047-1052.
3. Dudman NP, Temple SE, Guo XW, et al. Homocysteine enhances Neutrophil-endothelial interactions in both cultured human cells and rats in vivo. Circ Resear 1999;84:409-417.
4. Jaffe EA. Culture and identification of large vessel endothelial cells. In: Jaffe EA. Biology of Endothelial Cells. ed. Boston, Mass: Martinus Nijhoff 1984:1-13.
5. Harlan JM. Leukocyte-endothelial interactions. Blood 1985;65:513.
6. Meerschaert J, Furie MB. The adhesion molecules used by monocytes for migration across endothelium include CDI1a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium. J Immunol 1995;154:4099-4112.
7. Beekhuizen H, Blokland I, Corsel-van Tilburg AJ, et al. CD14 contributes to the adherence of human monocytes to cytokine-stimulated endothelial cells. J Immunol 1991;147:3761-3767.
8. Owen CA, Campbell EJ, Stockley RA. Monocyte adherence to fibronectin: role of CD11/CD18 integrins and relationship to other monocyte functions. J Leuk Biol 1992;51:400-408.
9. Nathan C, Srimal S, Farber C, et al. Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins. J Cell Biol 1989;109:1341-1349.
10. Guo XW, Dudman NP. Homocysteine induces expressions of adhesive molecules on leukocytes in whole blood. Chin Med J 2001;114:1235-1239.