Systematic changes in motor cortex cell activity with arm posture during directional isometric force generation

Journal of Neurophysiology

Volumn 89, Issue 1, 2003, Pages 212-228

  Sergio, Lauren E ^a   Kalaska, John F ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARM MUSCLE; ARTICLE; CONTROLLED STUDY; MALE; MOTOR CORTEX; MUSCLE FORCE; MUSCLE ISOMETRIC CONTRACTION; NERVE CELL EXCITABILITY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY;

ANIMALS; ARM; ELECTROMYOGRAPHY; HAND; ISOMETRIC CONTRACTION; MACACA MULATTA; MALE; MOTOR CORTEX; MOVEMENT; MUSCLE, SKELETAL; NEURONS; POSTURE; PSYCHOMOTOR PERFORMANCE; REGRESSION ANALYSIS;

EID: 0037246172     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00016.2002     Document Type: Article

References (75)

1. Ajemian R, Bullock D, and Grossberg S. Kinematic coordinates in which motor cortical cells encode movement direction. J Neurophysiol 84: 2191-2203, 2000.
2. Ashe J. Force and the motor cortex. Behav Brain Res. 87: 255-269, 1997.
3. Baraduc P, Guigon E, and Burnod Y. Recoding arm position to learn visuomotor transformations. Cereb Cortex 11: 906-917, 2001.
4. Bhushan N and Shadmehr R. Computational nature of human adaptive control during learning of reaching movements in force fields. Biol Cybern 81: 39-60, 1999.
5. Boussaoud D, Jouffrais C, and Bremmer F. Eye position effects on the neural activity of dorsal premotor cortex in the macaque monkey. J Neurophysiol 80: 1132-1150, 1998.
6. Boussaoud D and Bremmer F. Gaze effects in the cerebral cortex: reference frames for space coding and action. Exp Brain Res 128: 170-180, 1999.
7. Buchanan TS, Almdale DPJ, Lewis JL, and Rymer WZ. Characteristics of synergic relations during isometric contractions of human elbow muscles. J Neurophysiol 56: 1225-1241, 1986.
8. Buneo CA, Soechting JF, and Flanders M. Postural dependence of muscle actions: implications for neural control. J Neurosci 17: 2128-2142, 1997.
9. Burnod Y, Baraduc P, Battaglia-Mayer A, Guigon E, Koechlin E, Ferraina S, Lacquaniti F, and Caminiti R. Parieto-frontal coding of reaching: an integrated framework. Exp Brain Res 129: 325-346, 1999.
10. Cabel DW, Cisek P, and Scott SH. Neural activity in primary motor cortex related to mechanical loads applied to the shoulder and elbow during a postural task. J Neurophysiol 86: 2102-2108, 2001.
11. Caminiti R, Johnson PB, Galli C, Ferraina S, and Burnod Y. Making arm movements within different parts of space: the premotor and motor cortical representation of a coordinate system for reaching to visual targets. J Neurosci 11: 1182-1197, 1991.
12. Caminiti R, Johnson PB, and Urbano A. Making arm movements within different parts of space: dynamic aspects in the primate motor cortex. J Neurosci 10: 2039-2058, 1990.
13. Cisek P and Kalaska JF. Modest gaze-related discharge modulation in monkey dorsal premotor cortex during a reaching task performed with free fixation. J Neurophysiol 88: 1064-172, 2002.
14. Conditt MA, Gandolfo F, and Mussa-Ivaldi FA. The motor system does not learn the dynamics of the arm by rote memorization of past experience. J Neurophysiol 78: 554-560, 1997.
15. Crammond DJ and Kalaska JF. Differential relation of discharge in primary motor cortex and premotor cortex to movements versus actively maintained postures during a reaching task. Exp Brain Res 108: 45-61, 1996.
16. Crammond DJ and Kalaska JF. Prior information in motor and premotor cortex: activity during the delay period and effect on pre-movement activity. J Neurophysiol 84: 986-1005, 2000.
17. Desmurget M and Grafton S. Forward modeling allows feedback control for fast reaching movements. Trends Cognit Sci 1: 423-431, 2000.
18. Flanagan JR and Lolley S. The inertial anisotropy of the arm is accurately predicted during movement planning. J Neurosci 15: 1361-1369, 2001.
19. Flanagan JR and Wing AM. The role of internal models in motion planning and control: evidence from grip force adjustments during movements of hand-held loads. J Neurosci 17: 1519-1528, 1997.
20. Flanders M and Soechting JF. Arm muscle activation for static forces in three-dimensional space. J Neurophysiol 64: 1818-1837, 1990.
21. Flash T and Mussa-Ivaldi F. Human arm stiffness characteristics during the maintenance of posture. Exp Brain Res 82: 315-326, 1990.
22. Fromm C. Changes in steady state activity in motor cortex consistent with the length-tension relation of muscle. Pfluegers Arch 398: 318-323, 1983.
23. Georgopoulos AP, Ashe J, Smyrnis N, and Taira M. The motor cortex and the coding of force. Science 256: 1692-1695, 1992.
24. Georgopoulos AP, Caminiti R, Kalaska JF, and Massey JT. Spatial coding of movement: a hypothesis concerning the coding of movement direction by motor cortical populations. Exp Brain Res Suppl 7: 327-336, 1983.
25. Georgopoulos AP, Kettner RE, and Schwartz AB. Primate motor cortex and free arm movements to visual targets in three-dimensional space. II. Coding of the direction of arm movement by a neural population. J Neurosci 8: 2928-2937, 1988.
26. Georgopoulos AP, Lurito JT, Petrides M, Schwartz AB, and Massey JT. Mental rotation of the neuronal population vector. Science 243: 234-236, 1989.
27. Ghilardi MF, Gordon J, and Ghez C. Learning an visuomotor transformation in a local area of workspace produces directional biases in other areas. J Neurophysiol 73: 2535-2539, 1995.
28. Gordon J, Ghilardi MF, Cooper SE, and Ghez C. Accuracy of planar reaching movements. II. Systematic extent errors resulting from inertial anisotropy. Exp Brain Res 99: 112-130, 1994.
29. Hoffman DS, and Strick PL. Step-tracking movements of the wrist. IV: Muscle activity associated with movements in different directions. J Neurophysiol 81: 319-333, 1999.
30. Johnson MT, Mason CR, and Ebner TJ. Central processes for the multiparametric control of arm movements in primates. Curr Opin Neurobiol 11: 684-688, 2001.
31. Jordan MI. Motor learning and the degrees of freedom problem. In: Attention and Performance. XIII. Motor Representation and Control, edited by Jeannerod M. Hillside, NJ: Erlbaum, 1990, p. 796-836.
32. Jouffrais C and Boussaoud D. Neuronal activity related to eye-hand coordination in the primate premotor cortex. Exp Brain Res 128: 205-209, 1999.
33. Kakei S, Hoffman DS, and Strick PL. Muscle and movement representations in the primary motor cortex. Science 285: 2136-2139, 1999.
34. Kalaska JF, Cohen DA, Hyde ML, and Prud'Homme M. A comparison of movement direction-related versus load direction-related activity in primate motor cortex using a two-dimensional reaching task. J Neurosci 9: 2080-2102, 1989.
35. Kalaska JF and Hyde ML. Area 4 and area 5: differences between the load direction-dependent discharge variability of cells during active postural fixation. Exp Brain Res 59: 197-202, 1985.
36. Kalaska JF, Scott SH, Cisek P, and Sergio LE. Cortical control of reaching movements. Curr Opin Neurobiol 7: 849-859, 1997.
37. Kalaska JF, Sergio LE, and Cisek P. Cortical control of whole-arm motor tasks. In: Sensory Guidance of Movement. Novartis Foundation Symposium. New York: Wiley, 1998, vol. 218, p. 176-200.
38. Karst GM and Hasan Z. Initiation rules for planar two-joint arm movements: agonist selection for movements throughout the workspace. J Neurophysiol 66: 1579-1593, 1991a.
39. Karst GM and Hasan Z. Timing and magnitude of electromyographic activity for two-joint arm movements in different directions. J Neurophysiol 66: 1594-1604, 1991b.
40. Kawato M. Internal models for motor control and trajectory planning. Curr Opin Neurobiol 9: 718-727, 1999.
41. Krakhauer JW, Ghilardi MF, and Ghez C. Independent learning of internal models for kinematic and dynamic control of reaching. Nat Neurosci 2: 1026-1031, 1999.
42. Mardia KV. Statistics of Directional Data. London: Academic, 1972.
43. Massey JT, Drake RA, and Georgopoulos AP. Cognitive spatial-motor processes. IV. Specification of the direction of visually guided isometric forces in two-dimensional space: information transmitted and effects of visual force-feedback. Exp Brain Res 83: 439-445, 1991.
44. Moran DW and Schwartz AB. Motor cortical activity during drawing movements: population representation during spiral tracing. J Neurophysiol 82: 2693-2704, 1999a.
45. Moran DW and Schwartz AB. Motor cortical representation of speed and direction during reaching. J Neurophysiol 82: 2676-2692, 1999b.
46. Mussa-Ivaldi FA, Hogan N, and Bizzi E. Neural, mechanical, and geometric factors subserving arm posture in humans. J Neurosci 5: 2732-2743, 1985.
47. Pouget A and Sejnowski TJ. Spatial transformation in the parietal cortex using basis functions. J Cognit Neurosci 9: 222-237, 1997.
48. Ramsay JO and Silverman BW. Functional Data Analysis. New York: Springer-Verlag. 1997.
49. Sabes PN. The planning and control of reaching movements. Curr Opin Neurobiol 10: 740-746, 2000.
50. Salinas E and Abbott L. Transfer of coded information from sensory to motor networks. J Neurosci 15: 6461-6464, 1995.
51. Schwartz AB, Kettner RE, and Georgopoulos AP. Primate motor cortex and free arm movements to visual targets in three-dimensional space. I. Relations between single cell discharge and direction of movement. J Neurosci 8: 2913-2927, 1988.
52. Schwartz AB. Motor cortical activity during drawing movements: single-unit activity during sinusoid tracing. J Neurophysiol 68: 528-541, 1992.
53. Scott SH, Gribble PL, Graham KM, and Cabel DW. Dissociation between hand motion and population vectors from neural activity in motor cortex. Nature 413: 161-165, 2001.
54. Scott SH and Kalaska JF. Temporal changes in the effect of arm orientation on directional tuning of cells in monkey primary motor (MI) and dorsal premotor (PMd) cortex during reaching. Soc Neurosci Abstr 22: 1829, 1996.
55. Scott SH and Kalaska JF. Reaching movements with similar hand paths but different arm orientations. I. Activity of individual cells in motor cortex. J Neurophysiol 77: 826-853, 1997.
56. Scott SH, Sergio LE, and Kalaska JF. Reaching movements with similar hand paths but different arm orientations. II. Activity of individual cells in dorsal premotor cortex and parietal area 5. J Neurophysiol 78: 2413-2426, 1997.
57. Sergio LE and Kalaska JF. Systematic changes in directional tuning of motor cortex cell activity with hand location while generating static isometric forces in constant spatial directions. J Neurophysiol 78: 1170-1174, 1997a.
58. Sergio LE and Kalaska JF. The effect of arm posture on MI cell discharge during isometric force generation in constant spatial directions. Soc Neurosci Abstr 23: 607.2, 1997b.
59. Sergio LE and Kalaska JF. Changes in the temporal pattern of primary motor cortex activity in a directional isometric force versus limb movement task. J Neurophysiol 80: 1577-1583, 1998.
60. Shadmehr R and Moussavi ZMK. Spatial generalization from learning dynamics of reaching movements. J Neurosci 20: 7807-7815, 2000.
61. Shadmehr R and Mussa-Ivaldi FA. Adaptive representation of dynamics during learning of a motor task. J Neurosci 14: 3208-3224, 1994.
62. Shen L and Alexander GE. Preferential representation of instructed target location versus limb trajectory in dorsal premotor area. J Neurophysiol 77: 1195-1212, 1997a.
63. Shen L and Alexander GE. Neural correlates of a spatial sensory-to-motor transformation in primary motor cortex. J Neurophysiol 77: 1171-1194, 1997b.
64. Smyrnis N, Gourtzelidis P, and Evdokimidis I. A systematic error in 2-D arm movements increases with increasing delay between visual target presentation and movement execution. Exp Brain Res 131: 111-120, 2000.
65. Soechting JF and Flanders M. Sensorimotor representations for pointing to targets in three-dimensional space. J Neurophysiol 62: 582-594, 1989.
66. Taira M, Boline J, Smyrnis N, Georgopoulos AP, and Ashe J. On the relations between single cell activity in the motor cortex and the direction and magnitude of three-dimensional static isometric force. Exp Brain Res 109: 367-376, 1996.
67. Thoroughman KA and Shadmehr R. Electromyographic correlates of learning an internal model of reaching movements. J Neurosci 19: 8573-88, 1999.
68. Todorov E. Direct cortical control of muscle activation in voluntary arm movements: a model. Nat Neurosci 3: 391-398, 2000.
69. Van Zuylen EJ, Gielen CCAM, and Denier van der Gon JJ. Coordination and inhomogeneous activation of human arm muscles during isometric torques. J Neurophysiol 60: 1523-1548, 1988.
70. Wadman WJ, Denier van der Gon JJ, and Derksen RJ. Muscle activation patterns for fast goal-directed arm movements. J Hum Mov Stud 6: 19-37, 1980.
71. Winters JM and Woo S. (Editors). Multiple Muscle Systems: Biomechanics and Movement Organization. New York: Springer-Verlag, 1990.
72. Wolpert DM and Ghahramani Z. Computational principles of movement neuroscience. Nat Neurosci 3 Suppl: 1212-1217, 2000.
73. Wolpert DM, Ghahramani Z, and Jordan NI. An internal model for sensorimotor integration. Science 269: 1880-1882, 1995.
74. Zhang J, Riehle A, Requin J, and Kornblum S. Dynamics of single neuron activity in monkey primary motor cortex related to sensorimotor transformation. J Neurosci 17: 2227-2246, 1997.
75. Zipser D and Andersen RA. A back-propagation programmed network that simulates response properties of a subset of posterior parietal neurons. Nature 331: 679-684, 1988.