메뉴 건너뛰기




Volumn 55, Issue 1, 2003, Pages 62-67

NAT2 and CYP1A2 phenotyping with caffeine: Head-to-head comparison of AFMU vs. AAMU in the urine metabolite ratios

Author keywords

AAMU; AFMU; Caffeine; CYP1A2; NAT2; Phenotyping

Indexed keywords

1 METHYLURIC ACID; 1 METHYLXANTHINE; 1,7 DIMETHYLURIC ACID; 5 ACETAMIDO 6 AMINO 3 METHYLURACIL; 5 ACETAMIDO 6 FORMYLAMINO 3 METHYLURACIL; ACYLTRANSFERASE; CAFFEINE; CYTOCHROME P450 1A2; DRUG METABOLITE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

EID: 0037244653     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2003.01730.x     Document Type: Article
Times cited : (21)

References (25)
  • 1
    • 0025992864 scopus 로고
    • Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
    • Guengerich FP, Shimada T. Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chem Res Toxicol 1991;4: 391-407.
    • (1991) Chem Res Toxicol , vol.4 , pp. 391-407
    • Guengerich, F.P.1    Shimada, T.2
  • 2
    • 0028131808 scopus 로고
    • Genetic polymorphism in xenobiotic metabolism
    • Smith CAD, Smith G, Wolf CR. Genetic polymorphism in xenobiotic metabolism. Eur J Cancer 1994; 30A: 1921-1935.
    • (1994) Eur J Cancer , vol.30 A , pp. 1921-1935
    • Smith, C.A.D.1    Smith, G.2    Wolf, C.R.3
  • 3
    • 0021151820 scopus 로고
    • A simple test for acetylator phenotype using caffeine
    • Grant DM, Tang BK, Kalow W. A simple test for acetylator phenotype using caffeine. Br J Clin Pharmacol 1984;17: 459-464.
    • (1984) Br J Clin Pharmacol , vol.17 , pp. 459-464
    • Grant, D.M.1    Tang, B.K.2    Kalow, W.3
  • 4
    • 0026621673 scopus 로고
    • Racial and gender differences in N-acetyltransferase, xanthine oxidase, and CYP1A2 activities
    • Relling MV, Lin JS, Ayers GD, Evans WE. Racial and gender differences in N-acetyltransferase, xanthine oxidase, and CYP1A2 activities. Clin Pharmacol Ther 1992;52: 643-658.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 643-658
    • Relling, M.V.1    Lin, J.S.2    Ayers, G.D.3    Evans, W.E.4
  • 5
    • 0032426427 scopus 로고    scopus 로고
    • Determination of drug-metabolizing enzyme activityin vivo: Pharmacokinetic and statistical issues
    • Tucker GT, Rostami-Hodjegan A, Jackson PR. Determination of drug-metabolizing enzyme activityin vivo: pharmacokinetic and statistical issues. Xenobiotica 1998;28: 1255-1273.
    • (1998) Xenobiotica , vol.28 , pp. 1255-1273
    • Tucker, G.T.1    Rostami-Hodjegan, A.2    Jackson, P.R.3
  • 6
  • 7
    • 0023227456 scopus 로고
    • A urinary metabolite ratio that reflects systemic caffeine clearance
    • Campbell ME, Spielberg SP, Kalow W. A urinary metabolite ratio that reflects systemic caffeine clearance. Clin Pharmacol Ther 1987;42: 157-165.
    • (1987) Clin Pharmacol Ther , vol.42 , pp. 157-165
    • Campbell, M.E.1    Spielberg, S.P.2    Kalow, W.3
  • 9
    • 0027197152 scopus 로고
    • The use of caffeine for enzyme assays: A critical appraisal
    • Kalow W, Tang BK. The use of caffeine for enzyme assays: a critical appraisal. Clin Pharmacol Ther 1993;53: 503-514.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 503-514
    • Kalow, W.1    Tang, B.K.2
  • 10
    • 0031910445 scopus 로고    scopus 로고
    • Pharmacokinetics and effect on caffeine metabolism of the proton pump inhibitors, omeprazole, lansoprazole, and pantoprazole
    • Andersson T, Holmberg J, Röhss K, Walan A. Pharmacokinetics and effect on caffeine metabolism of the proton pump inhibitors, omeprazole, lansoprazole, and pantoprazole. Br J Clin Pharmacol 1998;45: 369-375.
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 369-375
    • Andersson, T.1    Holmberg, J.2    Röhss, K.3    Walan, A.4
  • 11
    • 0031863228 scopus 로고    scopus 로고
    • Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2, and xanthine oxidase activity determined with caffeine phenotyping
    • Kashuba ADM, Bertino JS, Kearns GL et al. Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2, and xanthine oxidase activity determined with caffeine phenotyping. Clin Pharmacol Ther 1998;63: 540-551.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 540-551
    • Kashuba, A.D.M.1    Bertino, J.S.2    Kearns, G.L.3
  • 12
    • 18844474725 scopus 로고    scopus 로고
    • Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenecity and urine flow
    • Sinués B, Sáenz MA, Lanuza J et al. Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenecity and urine flow. Cancer Epidemiol Biomarkers Prev 1999;8: 159-166.
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 159-166
    • Sinués, B.1    Sáenz, M.A.2    Lanuza, J.3
  • 13
    • 0032710101 scopus 로고    scopus 로고
    • Tacrine is not an ideal probe drug for measuring CYP1A2 activityin vivo
    • Larsen JT, Hansen LL, Brosen K. Tacrine is not an ideal probe drug for measuring CYP1A2 activityin vivo. Br J Clin Pharmacol 1999;48: 663-668.
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 663-668
    • Larsen, J.T.1    Hansen, L.L.2    Brosen, K.3
  • 15
    • 0024383059 scopus 로고
    • Potential artefacts in the use of caffeine to determine acetylation phenotype
    • Lorenzo B, Reidenberg MM. Potential artefacts in the use of caffeine to determine acetylation phenotype. Br J Clin Pharmacol 1989;28: 207-208.
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 207-208
    • Lorenzo, B.1    Reidenberg, M.M.2
  • 16
    • 0026879487 scopus 로고
    • Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites
    • Butler MA, Lang NP, Young JF et al. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. Pharmacogenetics 1992;2: 116-127.
    • (1992) Pharmacogenetics , vol.2 , pp. 116-127
    • Butler, M.A.1    Lang, N.P.2    Young, J.F.3
  • 17
    • 0037093680 scopus 로고    scopus 로고
    • Stability of 5-acetamido-6-formylamino-3-methyluracil in buffers and urine
    • Wong P, Villeneuve G, Tessier V et al. Stability of 5-acetamido-6-formylamino-3-methyluracil in buffers and urine. J Pharm Biomed Anal 2002;28: 693-700.
    • (2002) J Pharm Biomed Anal , vol.28 , pp. 693-700
    • Wong, P.1    Villeneuve, G.2    Tessier, V.3
  • 18
    • 0026670643 scopus 로고
    • Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers
    • Graf T, Broly F, Hoffmann F, Probst M, Meyer UA, Howald H. Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers. Eur J Clin Pharmacol 1992;43: 399-403.
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 399-403
    • Graf, T.1    Broly, F.2    Hoffmann, F.3    Probst, M.4    Meyer, U.A.5    Howald, H.6
  • 19
    • 0031745325 scopus 로고    scopus 로고
    • Acetylation polymorphism expression in patients before and after liver transplantation: Influence of host/graft genotypes
    • Bendriss EK, Bechtel YC, Paintaud G et al. Acetylation polymorphism expression in patients before and after liver transplantation: influence of host/graft genotypes. Pharmacogenetics 1998;8: 201-209.
    • (1998) Pharmacogenetics , vol.8 , pp. 201-209
    • Bendriss, E.K.1    Bechtel, Y.C.2    Paintaud, G.3
  • 20
    • 0025892853 scopus 로고
    • Caffeine as a metabolic probe: Validation of its use for acetylator phenotyping
    • Tang BK, Kadar D, Qian L, Iriah J, Yip J, Kalow W. Caffeine as a metabolic probe: validation of its use for acetylator phenotyping. Clin Phamacol Ther 1991;49: 648-657.
    • (1991) Clin Phamacol Ther , vol.49 , pp. 648-657
    • Tang, B.K.1    Kadar, D.2    Qian, L.3    Iriah, J.4    Yip, J.5    Kalow, W.6
  • 21
    • 0034467572 scopus 로고    scopus 로고
    • Correlation between acetylation phenotype and genotype in Chinese women
    • Zhao B, Seow A, Lee EJD, Lee HP. Correlation between acetylation phenotype and genotype in Chinese women. Eur J Clin Pharmacol 2000;56: 689-692.
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 689-692
    • Zhao, B.1    Seow, A.2    Lee, E.J.D.3    Lee, H.P.4
  • 22
    • 0027189936 scopus 로고
    • Acetylator phenotypingvia analysis of four caffeine metabolites in human urine by micellar electrokinetic capillary chromatography with multiwavelength detection
    • Guo R, Thormann W. Acetylator phenotypingvia analysis of four caffeine metabolites in human urine by micellar electrokinetic capillary chromatography with multiwavelength detection. Electrophoresis 1993;14: 547-553.
    • (1993) Electrophoresis , vol.14 , pp. 547-553
    • Guo, R.1    Thormann, W.2
  • 23
    • 0028022691 scopus 로고
    • Determination of caffeine and its metabolites in urine by high-performance liquid chromatography and capillary electrophoresis
    • Rodopoulos N, Norman A. Determination of caffeine and its metabolites in urine by high-performance liquid chromatography and capillary electrophoresis. Scand J Clin Lab Invest 1994;54: 305-315.
    • (1994) Scand J Clin Lab Invest , vol.54 , pp. 305-315
    • Rodopoulos, N.1    Norman, A.2
  • 24
    • 0035810721 scopus 로고    scopus 로고
    • Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment
    • Nyéki A, Biollaz J, Kesselring UW, Décosterd LA. Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment. J Chromatogr B 2001; 755: 73-84.
    • (2001) J Chromatogr B , vol.755 , pp. 73-84
    • Nyéki, A.1    Biollaz, J.2    Kesselring, U.W.3    Décosterd, L.A.4
  • 25
    • 0032890885 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N-acetyltransferase 2 and CYP1A2 activities
    • Fuchs P, Haefeli WE, Ledermann HR, Wenk M. Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N-acetyltransferase 2 and CYP1A2 activities. Eur J Clin Pharmacol 1999;54: 869-876.
    • (1999) Eur J Clin Pharmacol , vol.54 , pp. 869-876
    • Fuchs, P.1    Haefeli, W.E.2    Ledermann, H.R.3    Wenk, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.