Photodynamic therapy: Is it a valuable treatment option for actinic keratoses?

American Journal of Clinical Dermatology

Volumn 4, Issue 3, 2003, Pages 149-155

  Chamberlain, Alexander J ^a   Kurwa, Habib A ^a  

^a CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYACID; AMINOLEVULINIC ACID; AMINOLEVULINIC ACID METHYL ESTER; COLCHICINE; DICLOFENAC; FLUOROURACIL; IMIQUIMOD; KERATOLYTIC AGENT; NORDIHYDROGUAIARETIC ACID; PHOTOSENSITIZING AGENT; PORPHYRIN DERIVATIVE; PROTOPORPHYRIN; RETINOID; SALICYLIC ACID DERIVATIVE; TRICHLOROACETIC ACID;

ACTINIC KERATOSIS; CLINICAL TRIAL; CRYOTHERAPY; CURETTAGE; CYTOTOXICITY; DRUG METABOLISM; HUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; REVIEW; SAFETY; SENSITIZATION; SKIN ABRASION; TREATMENT FAILURE;

FEMALE; HUMANS; KERATOSIS; MALE; PATIENT SATISFACTION; PHOTOCHEMOTHERAPY; PROGNOSIS; RANDOMIZED CONTROLLED TRIALS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SUNLIGHT; TREATMENT OUTCOME;

EID: 0037244413     PISSN: 11750561     EISSN: None     Source Type: Journal    
DOI: 10.2165/00128071-200304030-00001     Document Type: Review

References (56)

1. Marks R, Ponsford MW, Selwood TS, et al. Non-melanotic skin cancer and solar keratoses in Victoria. Med J Aust 1983; 24: 619-22
2. Frost CA, Green AC. Epidemiology of solar keratoses. Br J Dermatol 1994; 131: 455-64
3. Memon AA, Tomenson JA, Bothwell J, et al. Prevalence of solar damage and actinic keratosis in a Merseyside population. Br J Dermatol 2000; 142: 1154-9
4. Salasche SJ. Epidemiology of actinic keratoses and squamous cell carcinoma. J Am Acad Dermatol 2000 Jan; 42: S4-7
5. Frost C, Williams G, Green A. High incidence and regression rates of solar keratoses in a Queensland community. J Invest Dermatol 2000 Aug; 115: 273-7
6. Callen JP, Bickers DR, Moy RL. Actinic keratoses. J Am Acad Dermatol 1997 April; 36: 650-3
7. Dinehart SM. The treatment of actinic keratoses. J Am Acad Dermatol 2000 Jan; 42: S25-8
8. Feldman SR, Fliescher AB, Williford PM, et al. Destructive procedures are the standard of care for treatment of actinic keratoses. J Am Acad Dermatol 1999; 40: 43-7
9. Marks R, Rennie G. Selwood TS. Malignant transformation of solar keratoses to squamous cell carcinoma. Lancet 1988; I: 795-7
10. Montgomery H, Dorffel J. Verruca senilis und keratoma senile. Arch Dermatol Syph 1932; 166: 286-96
11. Dodson JM, Hewett JE, Clark DP. Malignant potential of actinic keratoses and the controversy over treatment. Arch Dermatol 1991; 127: 1029-31
12. Marks R, Foley P, Goodman G, et al. Spontaneous remission of solar keratoses: the case for conservative management. Br J Dermatol 1986; 115: 649-55
13. Kinlen LJ, Sheil AGR, Peto J, et al. Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs. BMJ 1979; 11: 1461-6
14. Jeffes EW, McCullough JL, Weinstein GD, et al. Photodynamic therapy of actinic keratosis with topical 5-aminolevulinic acid. Arch Dermatol 1997; 133: 727-32
15. Lubritz RR, Smolewski SA. Cryosurgery cure rate of actinic keratoses. J Am Acad Dermatol 1982; 7: 631-2
16. Thai KE, Fergin P, Freeman M, et al. A prospective study of the use of cryosurgery for the treatment of actinic keratoses. Annals Dermatol Venereol 2002; 129: 1S177-8
17. Pearlman L. Weekly pulse dosing: effective and comfortable topical 5-flourouracil treatment of multiple facial actinic keratoses. J Am Acad Dermatol 1991; 25: 665-7
18. Coleman III WP, Yarborough JM, Mandy SH. Dermabrasion for prophylaxis and treatment of actinic keratoses. Dermatol Surg 1996 Jan; 22: 17-21
19. Sander CA, Pfeiffer C, Kligman AM, et al. Chemotherapy for disseminated actinic keratoses with 5-fluorouracil and isotretinoin. J Am Acad Dermatol 1997 Feb; 36: 236-8
20. Thorne EG. Long-term clinical experience with a topical retinoid. Br J Dermatol 1991; 41: 31-6
21. Olsen EA, Abernathy L, Kulp-Shorten C, et al. A double-blind vehicle-controlled study evaluating masoprocol cream in the treatment of actinic keratoses on the head and neck. J Am Acad Dermatol 1991; 24: 738-43
22. Grimaitre M, Etienne A, Fathi M, et al. Topical colchicine therapy for actinic keratoses. Dermatology 2000; 200: 346-8
23. Stockgleth E, Meyer T, Benninghoff B, et al. Successful treatment of actinic keratosis with imiquimod cream 5.0%: a report of 6 cases. Br J Dermatol 2001 May; 144: 1050-3
24. Rivers JK, Arlette J, Shear N, et al. Topical treatment of actinic keratoses with 3.0% diclofenac in 2.5% hyaluronan gel. Br J Dermatol 2002 Jan; 146: 94-100
25. Epstein E. Warning! Masoprocol is a potent sensitizer. J Am Acad Dermatol 1994; 31: 295-6
26. Drake LA, Ceilley RI, Cornelison RL, et al. Guidelines of care for actinic keratoses. J Am Acad Dermatol 1995; 32: 95-8
27. Wolling U, Konrad H, Karamfilov T. Treatment of common warts and actinic keratoses by Er:YAG laser. J Cutan Laser Ther 2001 Jun; 3: 63-6
28. Fritsch C, Goerz G, Ruzicka T. Photodynamic therapy in dermatology. Arch Dermatol 1998 Feb; 134: 207-14
29. Pass HI. Photodynamic therapy in oncology: mechanisms and clinical use. J Natl Cancer Inst 1993; 85: 443-56
30. Kalka K, Merk H, Mukhtar H. Photodynamic therapy in dermatology. J Am Acad Dermatol 2000 Mar; 42: 389-413
31. Gomer CJ. Preclinical examination of first and second-generation photosensitizers used in photodynamic therapy. Photochem Photobiol 1991; 54: 109-7
32. Kennedy JC, Pottier RH, Pross DC. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J Photochem Photobiol 1990; 6: 143-8
33. Wolf P, Rieger E, Kerl H. Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulinic acid: an alternative treatment modality for solar keratoses, superficial squamous cell carcinomas, and basal cell carcinomas? J Am Acad Dermatol 1993; 28: 17-21
34. Iinuma S, Farshi SS, Ortel B, et al. A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin. Br J Cancer 1994; 70: 21-8
35. Morton CA, Brown SB, Collins S, et al. Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group. Br J Dermatol 2002; 146: 552-67
36. Karrer S, Baumier W, Abels C, et al. Long-pulse dye laser for photodynamic therapy: investigations in vitro and in vivo. Lasers Surg Med 1999; 25: 51-9
37. Stables GI. Photodynamic therapy in dermatology. J Dermatol Treat 1999; 10: 213-9
38. Kennedy JC, Pottier RH. Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy. J Photochem Photobiol B 1992; 14: 275-92
39. Calzavara-Pinton PG. Repetitive photodynamic therapy with topical delta-aminolevulinic acid as an alternative approach to the routine treatment of superficial non-melanoma skin tumours. J Photochem Photobiol B 1995; 29: 53-7
40. Morton CA, Whitehurst C, Moseley H, et al. Development of an alternative light source to lasers for photodynamic therapy: 1. Clinical evaluation in the treatment of pre-malignant and non-melanoma skin cancer. Lasers Med Sci 1995; 10: 165-71
41. Fijan S, Hoenigsmann H, Ortel B. Photodynamic therapy of epithelial skin tumours using delta-aminolevulinic acid and desferrioxamine. Br J Dermatol 1995; 133: 282-8
42. Szeimies RM, Karrer S, Sauerwald A, et al. Photodynamic therapy with topical application of 5-aminolevulinic acid in the treatment of actinic keratoses: an initial clinical study. Dermatol 1996; 192: 246-51
43. Meijnders PJN, Star WM, De Bruijn RS, et al. Clinical results of photodynamic therapy for superficial skin malignancies or actinic keratoses using topical 5-aminolevulinic acid. Lasers Med Sci 1996; 11: 123-31
44. Fink-Puches R, Hopfer A, Smolle J, et al. Primary clinical response and long-term follow-up of solar keratoses treated with topically applied 5-aminolevulinic acid and irradiation by different wave bands of light. J Photochem Photobiol B 1997; 41: 145-51
45. Stefanidou M, Tosca A, Themelis G, et al. In vivo fluorescence kinetics and photodynamic therapy efficacy of delta-aminolevulinic acid-induced porphyrins in basal cell carcinomas and actinic keratoses; implications for optimization of photodynamic therapy. Eur J Dermatol 2000; 10: 351-6
46. Itoh Y, Ninomiya Y, Henta T, et al. Topical delta-aminolevulinic acid-based photodynamic therapy for Japanese actinic keratoses. J Dermatol 2000; 27: 513-8
47. Jeffes EW, McCullough JL, Weinstein GD, et al. Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light. J Am Acad Dermatol 2001; 45: 96-104
48. Markham T, Collins P. Topical 5-aminolevulinic acid photodynamic therapy for extensive scalp actinic keratoses. Br J Dermatol 2001; 145: 502-4
49. Varma S, Wilson H, Kurwa HA, et al. Bowen's disease, solar keratoses and superficial basal cell carcinomas treated by photodynamic therapy using a large-field incoherent light source. Br J Dermatol 2001; 144: 567-74
50. Lang K, Schulte KW, Ruzicka T, et al. Aminolevulinic acid (Levulan®) in photodynamic therapy of actinic keratoses. Skin Therapy Lett 2001 Sept; 6: 1-5
51. Fristch C, Stege H, Saalmann G, et al. Green light is effective and less painful than red light in photodynamic therapy of facial solar keratoses. Photodermatol Photoimmunol Photomed 1997; 13: 181-5
52. Ceburkov O, Gollnick H. Photodynamic therapy in dermatology. Eur J Dermatol 2000; 10: 568-76
53. Kurwa HA, Yong-Gee SA, Seed PT, et al. A randomized paired comparison of photodynamic therapy and topical 5-fluorouracil in the treatment of actinic keratoses. J Am Acad Dermatol 1999; 41: 414-8
54. Foley P, Freeman M, Vinciullo C, et al. A comparison of photodynamic therapy using metvix with cryotherapy in actinic keratosis [abstract]. J Eur Acad Dermatol Venereol 2001; 15 Suppl. 2: 223
55. Szeimies RM, Karrer S, Radakovic-Fijan S, et al. Photodynamic therapy using topical methyl 5-aminolevulinate compared with cryotherapy for actinic keratosis: a prospective randomized study. J Am Acad Dermatol 2002; 47: 258-62
56. Lang K, Lehmann P, Bolsen K, et al. Aminolevulinic acid: pharmacological profile and clinical indication. Expert Opin Investig Drugs 2001 Jun; 10: 1139-56