Small bowel allografts maintained by administration of Bombesin while under immunosuppression

Journal of Pediatric Surgery

Volumn 38, Issue 1, 2003, Pages 83-87

  Furukawa, Taizo ^a   Kimura, Osamu ^a   Go, Seitetsu ^a   Iwai, Naomi ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Bombesin; Crypt cell proliferation; Proliferative cell nuclear antigen; Small bowel transplantation; Thiry Vella fistula

Indexed keywords

BOMBESIN; CELL NUCLEUS ANTIGEN; EOSIN; HEMATOXYLIN; SODIUM CHLORIDE; TACROLIMUS;

ACUTE GRAFT REJECTION; ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL PROLIFERATION; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; CRYPT CELL; EPITHELIUM CELL; EVALUATION; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE GRAFT; INTESTINE VILLUS; LAMINA PROPRIA; MALE; MUCOSAL IMMUNITY; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT;

EID: 0037240831     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1053/jpsu.2003.50016     Document Type: Conference Paper

References (25)

1. Cicalese L, Sileri P, Green M, et al: Bacterial translocation in clinical intestinal transplantation. Transplantation 71:1414-1417, 2001
2. Todo S, Reyes J, Furukawa H, et al: Outcome analysis of 71 clinical intestinal transplantations. Ann Surg 222:270-280, 1995
3. Erspamer V, Erspamer GF, Inselvini M: Some pharmacological action of alytensin and bombesin. J Pharm Pharmacol 22:875-876, 1970
4. Lehy T, Puccio F: Influence of bombesin on gastrointestinal and pancreatic cell growth in adult and suckling animals. Ann N Y Acad Sci 547:255-267, 1988
5. Dembinski A, Konturek PK, Konturek SJ: Role of gastrin and cholecystokinin in the growth-promoting action of bombesin on the gastroduodenal mucosa and the pancreas. Regul Pept 27:343-354, 1990
6. Furukawa T, Kimura O, Iwai N, et al: The effect of bombesin on syngeneically transplanted intestinal mucosa. Transplant Proc 34:1025-1026, 2002
7. Mochik GJ, Russel PS: Transplantation of small bowel in the rat. Surgery 70:693-702, 1971
8. Wallander J, Holtz A, Larsson E, et al: Small-bowel transplantation in the rat with a nonsuture cuff technique. Transplant Int 1:135-139, 1988
9. Toyama N, Kobayashi E, Kamada N, et al: Small bowel transplantation in rats: Endoscopic and histological evaluation of graft rejection, Gastroenterol Jpn 28:209-217, 1993
10. Yoshikawa R, Utsunomiya J: Cell proliferation kinetics are abnormal in transitional mucosa adjacent to colorectal carcinoma. Br J Surg 83:36-39, 1996
11. Okuyama H, Urao M, Lee D, et al: The effect of epidermal growth factor on bacterial translocation in newborn rabbits. J Pediatr Surg 33:225-228, 1998
12. Helmrath MA, Shin CE, Erwin CR, et al: Epidermal growth factor upregulates the expression of its own intestinal receptor after small bowel resection. J Pediatr Surg 33:229-234, 1998
13. Byrne TA, Morrissey TB, Nattakom TV, et al: Growth hormone, glutamine, and a modified diet enhance nutrient absorption in patients with severe short bowel syndrome. JPEN J Parenter Enteral Nutr 19:296-302, 1995
14. Gomez de Segura IA, Prieto Y, Grande AG, et al: Growth hormone reduces mortality and bacterial translocation in irradiated rats. Acta Oncol 37:179-185, 1998
15. Chao JC, Donovan S: Effects of insulin, insulin-like growth factors and epidermal growth factor on mitogenesis and disaccharidase activity in rat (IEC-6) and human (FHs 74 Int) intestinal cells. Chin J Physiol 39:253-263, 1996
16. Chono E, Kurokawa T, Oda C, et al: Expression of rac 1 protein in the crypt-villus axis of rat small intestine: In reference to insulin action. Biochem Biophys Res Commun 233:455-458, 1997
17. Park JH, Vanderhoof JA: Growth hormone did not enhance mucosal hyperplasia after small-bowel resection. Scand J Gastroenterol 31:349-354, 1996
18. Shulman DI, Hu CS, Duckett G, et al: Effects of short-term growth hormone therapy in rats undergoing 75% small intestinal resection. J Pediatr Gastroenterol Nutr 14:3-11, 1992
19. Van der hoof JA, Kollman KA, Griffin S, et al: Growth hormone and glutamine do not stimulate intestinal adaptation following massive small bowel resection in the rat. J Pediatr Gastroenterol Nutr 25:327-331, 1997
20. Eizaguirre BI, Aldazabal P, Barrena MJ, et al: Effect of growth hormone, epidermal growth factor and insulin on bacterial translocation in experimental short bowel syndrome. J Pediatr Surg 35:692-695, 2000
21. Zhang W, Bain A, Rombeau JL: Insulin-like growth factor (IGF-I) and glutamine improve structure and function in the small bowel allograft. J Surg Res 14:6-12, 1995
22. Keith HM, Zarzaur BL, Fukatsu K, et al: Individual neuropeptides regulate gut-associated lymphoid tissue integrity, intestinal immunoglobulin A levels, and respiratory antibacterial immunity. J Parenter Enteral Nutr 24:261-268, 2000
23. ZarZaur BL, Wu Y, Fukatsu K, et al: The neuropeptide bombesin improves IgA-mediated mucosal immunity with preservation of gut interleukin-4 in total parenteral nutrition-fed mice. Surgery 131:59-65, 2002
24. DeWitt RC, Wu Y, Renege KB, et al: Bombesin recovers gut-associated lymphoid tissue and preserves immunity to bacterial pneumonia in mice receiving total parenteral nutrition. Ann Surg 231:1-8, 2000
25. Kimura O, Go S, Furukawa T, et al: Influence of bombesin on the intestinal mucosal immunologic response under immunosuppression. Transplant Proc 32:1269-1271, 2000