Conformational studies of novel estrogen receptor ligands by 1D and 2D NMR spectroscopy and computational methods

Magnetic Resonance in Chemistry

Volumn 41, Issue 4, 2003, Pages 246-252

  Sebag, Albert B ^a   Hanson, Robert N ^a   Forsyth, David A ^a   Lee, Choon Young ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

1D NOESY; 2D NOESY; Conformational studies; COSY; DEPT; Estrogen receptor ligands; HMQC; NMR

Indexed keywords

BINDING ENERGY; LIGANDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

1D AND 2D NMR SPECTROSCOPIES; 1D NOESY; 2D NOESY; CONFORMATIONAL STUDY; COSY; DEPT; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR LIGAND; HMQC; RECEPTOR LIGANDS;

CONFORMATIONS;

17ALPHA (2 TRIFLUOROMETHYLPHENYL)VINYLESTRADIOL; 17ALPHA (4 TRIFLUOROMETHYLPHENYL)VINYLESTRADIOL; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; LIGAND; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG CONFORMATION; HORMONE RECEPTOR INTERACTION; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR OCCUPANCY; STATISTICAL ANALYSIS; STRUCTURE ANALYSIS; THEORETICAL STUDY;

EID: 0037240217     PISSN: 07491581     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrc.1150     Document Type: Article

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