The role of sodium-hydrogen ion exchange in patients undergoing coronary artery bypass grafting

Journal of Cardiac Surgery

Volumn 18, Issue SUPPL. 1, 2003, Pages 21-26

  Bolli, Roberto ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARIPORIDE;

CALCIUM CELL LEVEL; CELL DEATH; CELL PH; CONFERENCE PAPER; CORONARY ARTERY BYPASS GRAFT; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART MUSCLE REPERFUSION; HEART PROTECTION; HUMAN; PROTON SODIUM EXCHANGE; STUNNED HEART MUSCLE;

ANTI-ARRHYTHMIA AGENTS; CLINICAL TRIALS; CORONARY ARTERY BYPASS; GUANIDINES; HUMANS; HYDROGEN-ION CONCENTRATION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIAL STUNNING; SODIUM-HYDROGEN ANTIPORTER; SULFONES;

EID: 0037240008     PISSN: 08860440     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1540-8191.18.s1.4.x     Document Type: Conference Paper

References (18)

1. American Heart Association. 2002 heart and stroke statistical update. [American Heart Association Web site]. Available at http://216.185.112.5/downloadable/heart/10148328094661013190990123HS_State_ 02.pdf. Accessed July 12, 2002.
2. Eagle KA, Berger PB, Calkins H, et al. ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Circulation 2002;105:1257-1267.
3. Eagle KA, Guyton RA, Davidoff R, et al. ACC/AHA guidelines for coronary artery bypass graft surgery: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 1999;34:1262-1347.
4. Ferguson TB Jr, Hammill BG, Peterson ED, et al. A decade of change - risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-99: A report from the STS National Database Committee and the Duke Clinical Research Institute. Society of Thoracic Surgeons. Ann Thorac Surg 2002;73:480-489.
5. Mangano DT. Cardiovascular morbidity and CABG surgery - a perspective: Epidemiology, costs, and potential therapeutic solutions. J Card Surg 1995;10:366-368.
6. Vinten-Johansen J, Thourani VH. Myocardial protection: An overview. J Extra Corpor Technol 2000;32:38-48.
7. Bolli R. Basic and clinical aspects of myocardial stunning. Prog Cardiovasc Dis 1998;40:477-516.
8. Breisblatt WM, Stein KL, Wolfe CJ, et al. Acute myocardial dysfunction and recovery: A common occurrence after coronary bypass surgery. J Am Coll Cardiol 1990;15:1261-1269.
9. Bolli R, Hartley CJ, Chelly JE, et al. An accurate, nontraumatic ultrasonic method to monitor myocardial wall thickening in patients undergoing cardiac surgery. J Am Coll Cardiol 1990;15:1055-1065.
10. Bolli R. Why myocardial stunning is clinically important. Basic Res Cardiol 1998;93:169-172.
11. Ballantyne CM, Verani MS, Short HD, et al. Delayed recovery of severely 'stunned' myocardium with the support of a left ventricular assist device after coronary artery bypass graft surgery. J Am Coll Cardiol 1987;10:710-712.
12. Baliga RR. Apoptosis in myocardial ischemia, infarction, and altered myocardial states. Cardiol Clin 2001;19:91-112.
13. Leem CH, Lagadic-Gossmann D, Vaughan-Jones RD. Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte. J Physiol 1999;517:159-180.
14. Karmazyn M. Mechanisms of protection of the ischemic and reperfused myocardium by sodium-hydrogen exchange inhibition. J Thromb Thrombolysis 1999;8:33-38.
15. Myers ML. Protection of the myocardium with sodium-hydrogen exchange inhibitors: A cardiac surgical perspective. J Thromb Thrombolysis 1999;8:53-60.
16. Theroux P, Chaitman BR, Danchin N, et al. Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Guard during ischemia against necrosis (GUARDIAN) Investigators. Circulation 2000;102:3032-3038.
17. Avkiran M. Rational basis for use of sodium-hydrogen exchange inhibitors in myocardial ischemia. Am J Cardiol 1999;83:10G-18G.
18. Scholz W, Jessel A, Albus U. Development of the Na+/H+ exchange inhibitor cariporide as a cardioprotective drug: From the laboratory to the GUARDIAN trial. J Thromb Thrombolysis 1999;8:61-70.