Merit and demerit of polyvalent snake antivenoms

Journal of Toxicology - Toxin Reviews

Volumn 22, Issue 1, 2003, Pages 77-89

  Ratanabanangkoon, Kavi ^a  

^a Mahidol University ^*  (Thailand)

Author keywords

Monovalent; Polyvalent; Snake antivenom

Indexed keywords

NEUTRALIZING ANTIBODY; POLYVALENT SNAKE ANTIVENOM; SNAKE VENOM; SNAKE VENOM ANTISERUM; UNCLASSIFIED DRUG;

ANAPHYLACTIC SHOCK; ANAPHYLAXIS; DRUG COST; DRUG EFFICACY; DRUG MANUFACTURE; DRUG POTENCY; DRUG PURITY; DRUG SAFETY; ENVENOMATION; GOOD MANUFACTURING PRACTICE; HUMAN; IMMUNIZATION; REVIEW; SERUM SICKNESS; SNAKEBITE; URTICARIA;

SERPENTES;

EID: 0037239894     PISSN: 07313837     EISSN: None     Source Type: Journal    
DOI: 10.1081/TXR-120019563     Document Type: Review

References (41)

1. Bogarin, G., Segura, E., Duran, G., Lomonte, B., Rojas, G., Gutierrez, J. M. (1995). Evaluation of neutralizing ability of four commercially available antivenoms against the venom of Bothrops asper from Costa Rica. Toxicon 33:1242-1247.
2. Boquet, P. (1979). Immunological properties of snake venoms. In: Lee, C. Y., ed. Snake Venoms. Berlin: Springer, pp. 751-824.
3. Braz, A., Minozzo, J., Abreu, J. C., Gubert, I. C., Chavez-Olortegui, C. (1999). Development and evaluation of the neutralizing capacity of horse antivenom against the Brazilian spider Loxosceles intermedia. Toxicon 37:1323-1328.
4. Chinonavanig, L., Billings, P. B., Matangkasombut, P., Ratanabanangkoon, K. (1988). Antigenic relationships and relative immunogenicities of venom proteins of six poisonous snakes of Thailand. Toxicon 26:883-890.
5. Chippaux, J. P., Goyffon, M. (1991). Production and use of snake antivenin. In: Tu, A. T., ed. Handbook of Natural Toxins. Vol. 5. New York: Marcel Dekker, pp. 529-555.
6. Chippaux, J. P., Goyffon, M. (1998). Venoms, antivenoms and immunotherapy. Toxicon 36:823-846.
7. 2 equine antivenom in 223 African snake envenomations: a field trial in Cameroon. VAO (Venin Afrique de l'Ouest) Investigators. Trans. R. Soc. Trop. Med. Hyg. 92:657-662.
8. 2: results of a clinical trial in northern Cameroon. Am. J. Trop. Med. Hyg. 61:1017-1018.
9. Chotwiwatthanakun, C., Pratanaphon, R., Akesowan, S., Sriprapat, S., Ratanabanangkoon, K. (2001). Production of potent polyvalent antivenom against three elapid venoms using a low dose, low volume, multi-site immunization protocol. Toxicon 39:1487-1494.
10. Christensen, P. A. (1979). Production and standardization of antivenin. In: Lee, C. Y., ed. Snake Venoms. Berlin: Springer, pp. 825-846.
11. Coetzer, P. W. W., Tilburg, C. R. (1982). The epidemiology of snakebite in northern Natal. S. Afr. Med. J. 62:206-212.
12. Coulter, A. R., Harris, R. D., Sutherland, S. K. (1980). Enzyme immunoassay for the rapid clinical identification of snake venom. Med. J. Aust. 1:433-435.
13. 2 antisnake venom by caprylic acid: a fast method for obtaining IgG fragments with high neutralization activity, purity and yield. Toxicon 27:297-303.
14. Ganthavorn, S. (1969). Toxicities of Thailand snake venoms and neutralization capacity of antivenin. Toxicon 7:239-241.
15. Gingrich, W. C., Hohenadel, J. C. (1956). Standardization of polyvalent antivenins. Venoms. Washington, DC: A.A.A.S.
16. Gutierrez, J. M., Gene, J. A., Rojas, G., Cerdas, L. (1985). Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom. Toxicon 23:887-893.
17. Karlson-Stiber, C., Persson, H., Heath, A., Smith, D., Al-Abdulla, I. H., SyÖstrom, L. (1997). First clinical experiences with specific sheep Fab fragments in snake bite. Report of a multicenter study of Vipera berus envenoming. J. Int. Med. 241:53-58.
18. Kittigul, L., Ratanabanangkoon, K. (1993). Reverse passive hemagglutination tests for rapid diagnosis of snake venoms. J. Immunoassay. 14: 105-127.
19. Kornalik, F., Taborska, E. (1989). Cross reactivity of mono- and polyvalent antivenoms with Viperidae and Crotalidae snake venoms. Toxicon 27:1135-1142.
20. Kukongviriyapan, V., Poopyruchpong, N., Ratanabanangkoon, K. (1982). Some parameters of affinity chromatography in the purification of antibody against Naja naja siamensis Toxin 3. J. Immunol. Methods 49:97-104.
21. Malasit, P., Warrell, D. A., Chanthavanich, P., Viravan, C., Mongkolsapaya, J., Singhthong, B., Supich, C. (1986). Prediction, prevention and mechanism of early (anaphylactic) antivenom reactions in victims of snake bites. Br. Med. J. 292:17-20.
22. 2 isolated from cobra venoms: neutralization by polyvalent antivenoms. Toxicon 24:1001-1008.
23. Mebs, D., Pohlmann, S., Von Tenspolde, W. (1988). Snake venom hemorrhagins: neutralization by commercial antivenoms. Toxicon 26:453-458.
24. Meyer, W. P., Habib, A. G., Onayade, A. A., Yakubu, A., Smith, D. C., Nasidi, A., Daudu, I. J., Warrell, D. A., Theakston, R. D. G. (1997). First clinical experiences with a new Fab Echis ocellatus snake bite antivenom in Nigeria: randomized comparative trial with Institute Pasteur Serum (IPSER) Africa antivenom. Am. J. Trop. Med. Hyg. 56:291-300.
25. Minton, S. A. Jr. (1979). Common antigens in snake venoms. In: Lee, C. Y., ed. Snake Venoms. Berlin: Springer, pp. 847-862.
26. Mohamed, A. H., Bakr, I. R., Kamel, A. (1966). Egyptian polyvalent antisnake bite serum; technique of preparation. Toxicon 4:69-72.
27. Moran, N. F., Newman, W. J., Theakston, R. D., Warrell, D. A., Wilkinson, D. (1998). High incidence of early anaphylactoid reaction to SAIMR polyvalent snake antivenom. Trans. R. Soc. Trop. Med. Hyg. 92:69-70.
28. Offerman, S. R., Smith, T. S., Derlet, R. W. (2001). Does the aggressive use of polyvalent antivenin for rattlesnake bites result in serious acute side effects? West. J. Med. 175:88-91.
29. Otero, R., Nunez, V., Osorio, R. G., Gutierrez, J. M., Giraldo, C. A., Posada, L. E. (1995). Ability of six Latin American antivenoms to neutralize the venom of mapana equis (Bothrops atrox) from Antioquia and Choco (Colombia). Toxicon 33:809-815.
30. Otero, R., Gutierrez, J. M., Nunez, V., Robles, A., Estrada, R., Segura, E., Toro, M. F., Garcia, M. E., Diaz, A., Ramirez, E. C., Gomez, G., Castaneda, J., Moreno, M. E. (1996). A randomized double-blind clinical trial of two antivenoms in patients bitten by Bothrops atrox in Colombia. The Regional Group on Antivenom Therapy Research (REGATHER). Trans. R. Soc. Trop. Med. Hyg. 90:696-700.
31. Pratanaphon, R., Akesowan, S., Khow, O., Sriprapat, S., Ratanabanangkoon, K. (1997). Production of highly potent horse antivenom against the Thai cobra (Naja kaouthia). Vaccine 15:1523-1528.
32. Pross, H. F., Eidinger, D. (1974). Antigenic competition: a review of nonspecific antigen-induced suppression. Adv. Immunol. 18:133-168.
33. Rojas, G., Jimenez, J. M., Gutierrez, J. M. (1994). Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production. Toxicon 32:351-363.
34. Sells, P. G., Jones, R. G., Laing, G. D., Smith, D. C., Theakston, R. D. (1994). Experimental evaluation of ovine antisera. to Thai cobra (Naja kaouthia) venom and its alpha-neurotoxin. Toxicon 32:1657-1665.
35. Smith, D. C., Krisana, R. R., Laing, G., Theakston, R. G. D., Landon, J. (1992). An affinity purified ovine antivenom for the treatment of Vipera berus envenoming. Toxicon 30:865-871.
36. Songsumard, S. (1995). Snakebite in Thailand. In: Annual Epidemiology Surveillance Report, Ministry of Public Health. pp. 324-333.
37. Sunthornandh, P., Matangkasombut, P., Ratanabanangkoon, K. (1992). Preparation, characterization and immunogenicity of various polymers and conjugates of elapid post-synaptic neurotoxins. Mol. Immunol. 29:501-510.
38. Tan, N. H., Choy, S. K., Chin, K. M., Ponnudurai, G. (1994). Cross-reactivity of monovalent and polyvalent Trimeresurus antivenoms with venoms from various species of Trimeresurus (lance-headed pit viper) snake. Toxicon 32:849-853.
39. Theakston, R. D., Laing, G. D., Fielding, C. M., Lascano, A. F., Touzet, J. M., Vallejo, F., Guderian, R. H., Nelson, S. J., Wuster, W., Richards, A. M. (1995). Treatment of snake bites by Bothrops species and Lachesis muta in Ecuador: laboratory screening of candidate antivenoms. Trans. R. Soc. Trop. Med. Hyg. 89:550-554.
40. Weinstein, S. A., Schmidt, J. J., Smith, L. A. (1991). Protein lethal toxins and cross-neutralization of venoms from the African water cobras, Boulengerina annulata annulata and Boulengerina christyi. Toxicon 29:1315-1327.
41. White, J. (1998). Envenoming and antivenom use in Australia. Toxicon 36:1483-1492.