Propofol anaesthesia and metabolic acidosis in children

Paediatric Anaesthesia

Volumn 13, Issue 1, 2003, Pages 53-57

  Özlü, Onur ^a,d   Özkara, H Asuman ^b   Eris, Senay ^a   Öcal, Turgay ^c  

^a Pediatric Hematology Oncology Clinic   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

^c HACETTEPE UNIVERSITY   (Turkey)

^d NONE   (Turkey)

Author keywords

Children; Metabolic acidosis; Propofol

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; HALOTHANE; HEART ENZYME; LACTATE DEHYDROGENASE; LIVER ENZYME; PHOSPHOTRANSFERASE; PROPOFOL; THIOPENTAL;

ACID BASE BALANCE; ANESTHESIA; ARTICLE; BLOOD SAMPLING; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INFUSION; HUMAN; METABOLIC ACIDOSIS; PH; POSTOPERATIVE PERIOD; PRIORITY JOURNAL;

ACIDOSIS; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; BLOOD GAS ANALYSIS; CHILD; CHILD, PRESCHOOL; HALOTHANE; HUMANS; LIVER; MYOCARDIUM; PROPOFOL; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 0037238109     PISSN: 11555645     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9592.2003.00965.x     Document Type: Article

References (16)

1. Browne BL, Prys-Roberts C, Wolf AR. Propofol and alfentanil in children. infusion technique and dose requirement for total iv anaesthesia. Br J Anaesth 1992; 69: 570-576.
2. Richards MJ, Skues MA, Jarvis AP et al. Total iv anaesthesia with propofol and alfentanil. dose requirements for propofol and the effect of premedication with clonidine. Br J Anaesth 1990; 65: 157-163.
3. Vangerven M, Hemelrijck J, Wouters P et al. Light anaesthesia with propofol for paediatric MRI. Anaesthesia 1992; 47: 706-707.
4. Aun CS, Sung RYO, Mera ME et al. Cardiovascular effects of iv induction in children: comparison between propofol and thiopentone. Br J Anaesth 1993; 70: 647-653.
5. Susla GM. Propofol toxicity in critically ill pediatric patients. Show us the proof. Crit Care Med 1998; 26: 1959-1960.
6. Bray RJ. Propofol infusion syndrome in children. Paed Anaesth 1998; 8: 491-499.
7. Parke TJ, Stevens JE, Rice ASC et al. Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports. BMJ 1992; 305: 613-616.
8. Strickland RA, Murray MJ. Fatal metabolicacidosis in a pediatric patient receiving an infusion of propofol in the intensive care unit: is there a relationship? Crit Care Med 1995; 23: 405-408.
9. Hanna JP, Ramundo ML. Rhabdomyolysis and hypoxia associated with prolonged propofol infusion in children. Neurology 1998; 50: 301-303.
10. Hatch DJ. Propofol infusion syndrome in children. Lancet 1999; 353: 1117-1118.
11. Saint-Maurice C, Cockshott ID, Douglas EJ et al. Pharmacokinetcs of propofol in young children after a single dose. Br J Anaesth 1989; 63: 667-670.
12. Marsh B, White M, Morton N et al. Pharmacokinetic model driven infusion of propofol in children. Br J Anaesth 1991; 67: 41-48.
13. Browne BL, Wolf AR. Prys-Roberts. Dose requirements for propofol in children during total iv anaesthesia. Br J Anaesth 1990; 64: 396P.
14. Ohkawa H, Iwakawa T, Ohtomo N et al. Clinical study on intraoperative hyperketonemia in non-diabetic surgical patients under general anesthesia. Masui 1993; 42: 1803-1807.
15. Martin PH, Murthy BVS, Petros AJ. Metabolic, biochemical and haemodynamic effects of infusion of propofol for long-term sedation of children undergoing intensive care. Br J Anaesth 1997; 79: 276-279.
16. D'Souza JP, Sine HE, Horvitz RA et al. The significance of the MB isoenzyme in patients with acute cardiovascular disease with a normal or borderline total CPK activity. Clin Biochem 1978; 11: 204-209.