Treatment of neonatal abstinence syndrome

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 88, Issue 1, 2003, Pages

  Johnson, K ^a   Gerada, C ^b   Greenough, A ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b Hurley Clinic   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CHLORAL HYDRATE; CHLORPROMAZINE; CLONIDINE; COCAINE; DIAMORPHINE; DIAZEPAM; METHADONE; MORPHINE; OPIATE; PAREGORIC; PETHIDINE; PHENOBARBITAL;

APNEA; BRAIN DYSFUNCTION; CLINICAL FEATURE; CLINICAL TRIAL; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG EXCRETION; DRUG INDICATION; DRUG MECHANISM; DRUG METABOLISM; GASTROINTESTINAL SYMPTOM; HEART DISEASE; HEMATOLOGIC DISEASE; HOSPITALIZATION; HUMAN; HYPOVENTILATION; METABOLIC DISORDER; MULTIPLE DRUG ABUSE; MUSCLE HYPOTONIA; NAUSEA; NEWBORN; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RESPIRATION DEPRESSION; RETROSPECTIVE STUDY; REVIEW; SEIZURE; SUCKING; TREATMENT OUTCOME; VOMITING; WELLBEING; WITHDRAWAL SYNDROME;

EID: 0037235079     PISSN: 00039888     EISSN: 13592998     Source Type: Journal    
DOI: 10.1136/fn.88.1.f2     Document Type: Review

References (53)

1. Farkas AG, Colbert DL, Erskine KJ. Anonymous testing for drug abuse in an antenatal population. Br J Obstet Gynaecol 1995;102:563-4.
2. Sherwood RA, Keating J, Kavvadia V, et al. Substance misuse in early pregnancy and relationship to fetal outcome. Eur J Pediatr 1999;158:488-92.
3. Milner AD, Marsh MJ, Ingram DM, et al. Effects of smoking in pregnancy on neonatal lung function. Arch Dis Child Fetal Neonatal Ed 1999;80:F8-14.
4. English DR, Hulse GK, Milne E, et al. Maternal cannabis use and birthweight: a meta-analysis. Addiction 1997;92:1553-60.
5. Gillogley KM, Evans AT, Hansen RL, et al. The perinatal impact of cocaine, amphetamine, and opiate use detected by universal intrapartum screening. Am J Obstet Gynecol 1990;163:1535-42.
6. Lissauer T, Ghaus K, Rivers RPA. Maternal drug abuse: effects on the child. Current Paediatrics 1994;4:235-9.
7. Edelin KC, Gurganious L, Golar K, et al. Methadone maintenance in pregnancy: consequences to care and outcome. Obstet Gynecol 1988;71:399-404.
8. Kandall SR, Albin S, Gartner LM, et al. The narcotic-dependent mother: fetal and neonatal consequences. Early Hum Dev 1977;1:159-69.
9. Wilson GS, Desmond MM, Wait RB. Follow-up of methadone treated and untreated narcotic dependent women and their infants: Health developmental and social implications. J Pediatr 1981;98:716-22.
10. Chasnoff IJ, Landress HJ, Barrett ME. The prevalence of illicit-drug use during pregnancy and discrepancies in mandatory reporting in Pinellas County, Florida. N Engl J Med 1990;322:1202-6.
11. Coghlan D, Milner M, Clarke T, et al. Neonatal abstinence syndrome. Ir Med J 1999;92:232-3.
12. Blumenthal I, Lindsay S. Neonatal barbiturate withdrawal. Postgrad Med J 1977;53:157-8.
13. Desmond MM, Schwanecke RP, Wilson GS, et al. Maternal barbiturate utilization and neonatal withdrawal symptomatology. J Pediatr 1972;80:190-7.
14. Brown HL, Britton KA, Mahaffey D, et al. Methadone maintenance in pregnancy: a reappraisal. Am J Obstet Gynecol 1998;179:459-63.
15. King TA, Perlman JM, Laptook AR, et al. Neurologic manifestations of in utero cocaine exposure in near term and term infants. Pediatrics 1995;96:259-64.
16. Delaney-Black V, Covington C, Ostrea E, et al. Prenatal cocaine and neonatal outcome: evaluation of dose-response relationship. Pediatrics 1996;98:735-40.
17. Napiorkowski B, Lester BM, Freier MC, et al. Effect of in utero exposure on infant neurobehaviour. Pediatrics 1996;98:71-5.
18. Fulroth R, Phillips B, Durand DJ. Perinatal autcome of infants exposed to cocaine and/or heroin in utero. American Journal of Diseases in Children 1989;143:905-10.
19. Strauss ME, Andresko M, Stryker JC, et al. Methadone maintenance during pregnancy: pregnancy, birth and neonate characteristics. Am J Obstet Gynecol 1974;120:895-900.
20. van Baar AL, Fleury P, Soepatmi S, et al. Neonatal behaviour after drug dependent pregnancy. Arch Dis Child 1989;64:235-40.
21. Morrison CL, Siney C. A survey of the management of neonatal opiate withdrawal in England and Wales. Eur J Pediatr 1996;155:323-6.
22. Beitner DB, Duman RS, Nestler EJ. A novel action of morphine in the rat locus ceruleus: persistent decrease in adenylate cyclase. Mol Pharmacol 1989;35:559-64.
23. Duman RS, Tallman JF, Nestler EJ. Acute and chronic opiate regulation of adenylate-cyclase in brain: specific effects in locus ceruleus. J Pharmacol Exp Ther 1988;246:1033-9.
24. Di Chiara G, North RA. Neurobiology of opiate abuse. Trends Pharmacol Sci 1992;13:185-93.
25. Aghajanian GK. Tolerance of locus ceruleus neurones to morphine and suppression of withdrawal response by clonidine. Nature 1978;276:186-8.
26. Little PJ, Price RR, Hinton RK, et al. Role of noradrenergic hyperactivity in neonatal opiate abstinence. Drug Alcohol Depend 1996;41:47-54.
27. Rasmussen K, Beitner-Johnson DB, Krystal JH, et al. Opiate withdrawal and the rat locus ceruleus: behavioural, electrophysiological and biochemical correlates. J Neurosci 1990;10:2308-17.
28. Holtzman SG, Sung YF. Pain control with opioid analgesics. In: Brody T, Larner J, Minneman K, eds. Human pharmacology. Chicago: Mosby, 1998:395-407.
29. Rech RH. Drugs used to treat anxieties and other related disorders. In: Brody T, Larner J, Minneman K, eds. Human pharmacology. Chicago: Mosby, 1998:365-71.
30. Hoder EL, Leckman JF, Poulsen J, et al. Clonidine treatment of neonatal narcotic abstinence syndrome. Psychiatry Res 1984;13:243-51.
31. Nathensen G, Golden GS, Litt IF. Diazepam in the management of the neonatal narcotic withdrawal syndrome. Pediatrics 1971;48:523-7.
32. Finnegan LP, Connaughton JF, Kron RE, et al. Neonatal abstinence syndrome: assessment and management. Addict Dis 1975;2:141-58.
33. Kron RE, Litt M, Finnegan LP. Narcotic addiction in the newborn: differences in behavior generated by methadone and heroin. Int J Clin Pharmacol Ther Toxicol 1975;12:63-9.
34. Kron RE, Litt M, Phoenix MD, et al. Neonatal narcotic abstinence: effects of pharmacotherapeutic agents and maternal drug usage on nutritive sucking behavior. J Pediatr 1976;88:637-41.
35. Rivers RPA. Infants of drug addicted mothers, In: Rennie JM, Roberton NRC, eds. Textbook of neonatology. Edinburgh: Churchill Livingston, 1999:443-51.
36. Herzlinger RA, Kandall SR, Vaughan HG. Neonatal seizures associated with narcotic withdrawal. J Pediatr 1977;91:638-41.
37. Pacifico P, Nardelli E, Pantarotto MF. Neonatal heroin withdrawal syndrome: evaluation of different pharmacological treatments. Pharmacol Res 1989;21:63-4.
38. Kandall SR, Doberczak TM, Mauer KR, et al. Opiate vs CNS depressant therapy in neonatal drug abstinence syndrome. American Journal of Diseases in Children 1983;137:378-82.
39. Kahn E, Neumann L, Polk GA. The course of the heroin withdrawal syndrome in newborn infants treated with phenobarbital or chlorpromazine. Pediatrics 1969;75:495-500.
40. Kaltenbach K, Finnegan LP. Neonatal abstinence syndrome: pharmacotherapy and developmental outcome. Neurobehav Toxicol Teratol 1986;8:353-5.
41. Carin I, Glass L, Parekh A, et al. Neonatal methadone withdrawal. Effect of two treatment regimens. American Journal of Diseases in Children 1983;137:1166-9.
42. Madden JD, Chappel JN, Zuspan F, et al. Observation and treatment of neonatal narcotic withdrawal. Am J Obstet Gynecol 1977;127:199-201.
43. Finnegan LP, Ehrlich S. Maternal drug abuse during pregnancy: evaluation and pharmacotherapy for neonatal abstinence. Modern Methods in Pharmacology 1990;6:255-63.
44. Finnegan LP, Michael H, Leifer B, et al. An evaluation of neonatal abstinence treatment modalities. NIDA Research Monograph 1984;49:282-8.
45. Coyle MG, Ferguson A, Lagasse L, et al. Diluted tincture of opium (DTO) and phenobarbital versus DTO alone for neonatal opiate withdrawal in term infants. J Pediatr 2002;140:561-4.
46. Hamunen K. Ventilatory effects of morphine, pethidine and methadone in children. Br J Anaesth 1993;70:414-18.
47. Glass L, Rajegowda BK, Kahn EJ, et al. Effect of heroin withdrawal on the respiratory rate and acid-base status in the newborn. N Engl J Med 1972;286:746-8.
48. Glass J, Rajecowda BK, Evans HE. Absence of respiratory distress syndrome in premature infants of heroin-addicted mothers. Lancet 1971;ii:685-6.
49. Taeusch HW, Carson SH, Wang NS, et al. Heroin induction of lung maturation and growth retardation. J Pediatr 1973;82:869-75.
50. American Academy of Pediatrics Committee on Drugs. Neonatal drug withdrawal. Pediatrics 1998;101:1079-88.
51. Schiff D, Chan G, Stern L. Fixed drug combinations and the displacement of bilirubin from albumin. Pediatrics 1971;48:139-41.
52. Morselli PL, Principi N, Tognoni G, et al. Diazepam elimination in premature and full term infants and children. J Perinat Med 1973;1:133-41.
53. Cree JE, Meyer J, Hailey DM. Diazepam in labour: its metabolism and effect on the clinical condition and thermogenesis of the newborn. BMJ 1973;4:251-5.