STAT5a regulates the GlcNAc-1-phosphate transferase gene transcription and expression

Cellular Physiology and Biochemistry

Volumn 13, Issue 2, 2003, Pages 85-92

  Zhang, Xiao Lian ^a   Qu, Xue Ju ^a   Vijay, Inder K ^b  

^a WUHAN UNIVERSITY   (China)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

Dpagt2; EMSA; Promoter; STAT5; Transfection

Indexed keywords

DOLICHYLPHOSPHATE ALPHA N ACETYLGLUCOSAMINE PHOSPHOTRANSFERASE 2; GLUCOCORTICOID RECEPTOR; LUCIFERASE; PHOSPHORUS 32; PHOSPHOTRANSFERASE; PROLACTIN RECEPTOR; STAT PROTEIN; STAT5A PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; FEMALE; FIBROBLAST; GEL MOBILITY SHIFT ASSAY; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN FUNCTION; TRANSCRIPTION REGULATION;

EID: 0037235064     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000070252     Document Type: Article

References (17)

1. Gao N, Lehrman MA: Coupling of the dolichol-P-P-oligosaccharide pathway to translation by perturbation-sensitive regulation of the initiating enzyme GlcNAc-1-P transferase. J Biol Chem 2002;277:39425-39435.
2. Marquardt T, Freeze H: Congenital disorders of glycosylation: glycosylation defects in man and biological models for their study. Biol Chem 2001;382:161-177.
3. Chantret I, Dupre T, Delenda C, Bucher S, Dancourt J, Barnier A, Charollais A, Heron D, Bader-Meunier B, Danos O, Seta N, Durand G, Oriol R, Codogno P, Moore SE: Congenital disorders of glycosylation type Ig is defined by a deficiency in dolichyl-P-mannose: Man7GlcNAc2-PP-dolichyl mannosyltransferase. J Biol Chem 2002;277:25815-25822.
4. Abeijon C, Hirschberg CB: Topography of initiation of N-glycosylation reactions. J Biol Chem 1990;265:14691-14695.
5. Ma J, H Saito, Oka T, Vijay IK: Negative regulatory element involved in the hormonal regulation of GlcNAc-1-P transferase gene in mouse mammary gland. J Biol Chem 1996;271:11197-11203.
6. Rajput B, Ma J, Muniappa N, Schantz L, Naylor SL, Lalley PA, Vijay IK: Mouse UDP-GlcNAc: dolichyl phosphate N-acetylglucosaminephosphotransferase. Molecular cloning of the cDNA, generation of anti-peptide antibodies and chromosomal localization. Biochem J 1992;285:985-992.
7. Rajput B, Ma J, Vijay IK: Structure and Organization of Mouse GlcNAc-1-phosphate Transferase Gene. J Biol Chem 1994;269:9590-9597.
8. Darnell Jr JE: STATs and Gene Regulation. Science 1997;277:1630-16358.
9. Hennighauseb L, Robinson GW, Wagner K-U, Liu X: Prolactin Signaling in Mammary Gland Development. J Biol Chem 1997;272:7567-7569.
10. Rajput B, Muniappa N, Vijay IK: Developmental and Hormonal Regulation of UDP-GlcNAc:Dolichol Phosphate GlcNAc-1-P Transferase in Mouse Mammary Gland. J Biol Chem 1994;269:16054-16061.
11. Saito H, Oka T: Hormonally regulated double- and single-stranded DNA-binding complexes involved in mouse beta-casein gene transcription. J Biol Chem 1996;271:8911-8918.
12. Wakao H, Gouilleux F, Groner B: Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J 1994;13:2182-2191.
13. Schindler CW: Series Introduction: JAK-STAT signaling in human disease. J Clin Invest 2002;109:1139-1142.
14. O'Shea JJ, Gadina M, Schreiber RD: Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 2002;109:Suppl. S121-131.
15. Bromberg J: Stat proteins and oncogenesis. J Clin Invest 2002;109:1139-1142.
16. Chida D, Wakao H, Yoshimura A, Miyajima A: Transcriptional regulation of the beta-casein gene by cytokines: cross-talk between STAT5 and other signaling molecules. Mol Endocrinol 1998;12:1792-1806.
17. Moriggl R, Berchtold S, Friedrich K, Standke GJ, Kammer W, Heim M, Wissler M, Stocklin E, Gouilleux F, Groner B: Comparison of the Transactivation Domains of Stat5 and Stat6 in Lymphoid cells and mammary epithelial cells. Mol Cellular Biol 1997;17:3663-3678.