Response: Mechanism of action of high-dose factor VIIa

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 23, Issue 1, 2003, Pages 10-

  Mann, Kenneth G ^a   Butenas, Saulius ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; PHOSPHOLIPID; RECOMBINANT BLOOD CLOTTING FACTOR 7A; THROMBIN; THROMBOPLASTIN;

BLEEDING; DRUG MECHANISM; EDITORIAL; HEMOPHILIA; HEMOPHILIA A; HEMOPHILIA B; HEMOSTASIS; PRIORITY JOURNAL; THROMBOCYTE;

EID: 0037233946     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000047646.64969.8B     Document Type: Editorial

References (11)

1. Hedner U. Recombinant factor VIIa (NovoSeven) as a hemostatic agent. Semin Hematol. 2001;38(suppl 12):43-47.
2. Santagostino A, Morfini M, Rocino A, Baudo F, Scaraggi FA, Gringeri A. Relationship between factor VII activity and clinical efficacy of recombinant factor VIIa given by continuous infusion to patients with factor VIII inhibitors. Thromb Haemost. 2001;86:954-958.
3. Smith MP, Ludlam CA, Collins PW, Hay SRM, Wilde JT, Grigeri A, Melsen T, Savidge GF. Elective surgery on factor VIII inhibitor patients using continuous infusion of recombinant activated factor VII. Thromb Haemost. 2001;86:949-953.
4. Henderson N, Key NS, Christie B, Kisiel W, Foster D, Nelsestuen GL. Response of factor VIII and IX-deficient blood to wild type and high membrane affinity mutant factor VIIa in an in vitro whole blood clotting assay: possible correlation to clinical outcome. Thromb Haemost. 2002;88:98-103.
5. Butenas S, Brummel KE, Branda RF, Paradis SG, Mann KG. Mechanism of factor VIIa-dependent coagulation in hemophilia blood. Blood. 2002;99:923-930.
6. Butenas S, Brummel KE, Paradis SG, Mann KG. Influence of factor VIIa and phospholipids on coagulation in "acquired" hemophilia. Arterioscler Thromb Vasc Biol. 2002;22:123-129.
7. Butenas S, Branda RF, van't Veer C, Cawthern KM, Mann KG. Platelets and phospholipids in tissue factor-initiated thrombin generation. Thromb Haemost. 2001:86:660-667.
8. Giles AR, Nesheim ME, Hoogendoorn H, Tracy PB, Mann KG. The coagulant-active phospholipid content is a major determinant of in vivo thrombogenicity of prothrombin complex (Factor IX) concentrates in rabbits. Blood. 1982;59:401-407.
9. Giles AR, Nesheim ME, Hoogendoorn H, Tracy PB, Mann KG. Stroma free human platelet lysates potentiate the in vivo thrombogenicity of factor Xa by the provision of coagulant-active phospholipid. Br J Haematol. 1982;51:457-468.
10. Monroe DM, Hoffman M, Oliver JA, Roberts HR. Platelet activity of high-dose factor VIIa is independent of tissue factor. Br J Haematol. 1997;99:542-547.
11. Hoffman M, Monroe DM, Roberts HR. Activated factor VII activates factors IX and X on the surface of activated platelets: thoughts on the mechanism of action of high-dose activated factor VII. Blood Coagul Fibrinolysis. 1998:9(suppl 1):S61-S65.