Monitoring of acid-base status of workers at a methyl methacrylate and polymethyl methacrylate production plant in bulgaria

American Industrial Hygiene Association Journal

Volumn 64, Issue 1, 2003, Pages 11-16

  Prakova, Gospodinka R ^a  

^a TRAKIA UNIVERSITY   (Bulgaria)

Author keywords

Acid base status; Methyl methacrylate

Indexed keywords

METHACRYLIC ACID METHYL ESTER; METHANOL; POLY(METHYL METHACRYLATE);

ACID BASE BALANCE; ADULT; AIR MONITORING; ARTICLE; BICARBONATE BLOOD LEVEL; BLOOD CARBON DIOXIDE TENSION; BLOOD PH; BULGARIA; CONTROLLED STUDY; HUMAN; LUNG VENTILATION; MAJOR CLINICAL STUDY; MAXIMUM ALLOWABLE CONCENTRATION; METABOLIC ACIDOSIS; OCCUPATIONAL EXPOSURE; OXYGEN TENSION; RESPIRATORY ACIDOSIS;

ACID-BASE IMBALANCE; BULGARIA; CHEMICAL INDUSTRY; HUMANS; METHYLMETHACRYLATE; OCCUPATIONAL EXPOSURE; POLYMETHYL METHACRYLATE; PROTECTIVE CLOTHING; VASODILATOR AGENTS;

EID: 0037230038     PISSN: 15428117     EISSN: None     Source Type: Journal    
DOI: 10.1080/15428110308984774     Document Type: Article

References (27)

1. World Health Organization (WHO): Concise International Chemical Assessment. Document N4. Methyl methacrylate. Geneva: WHO, 1998.
2. Govila, A.: Use of methyl methacrylate in bone reconstruction. Br. J. Plastic Surg. 43:210–217 (1990).
3. Kaaber, S.: Allergy to dental materials with special reference to the use of amalgam and polymethylmethacrylate. Int. Dent. J. 40:359–365 (1990).
4. Raje, R., S. Ahmad, and S. Weisbroth: Methyl methacrylate: Tissue distribution and pulmonary damage in rats following acute inhalation. Res. Comm. Chem. Pathol. Pharmacol. 50:151–154 (1985).
5. Cary, R., L. Morris, J. Cocker, et al.: Methyl Methacrylate, Criteria for an Occupational Exposure Limit. London: UK Health and Safety Executive, 1995.
6. Chan, P.C., S.L. Eustis, J.E. Huff, et al.: Two-year inhalation carcinogenesis studies of methyl methacrylate in rats and mice: Inflammation and degeneration of nasal epithelium. Toxicology 52:237–252 (1988).
7. Tansy, M.F., and F.M. Kendall: Update on the toxicity of inhaled methyl methacrylate vapor. Drug Chem. Toxicol. 2:315–330 (1979).
8. Matveeva, V.A., G.S. Saliamon, and L.A. Tiunova: About mechanism of toxicological action of the methylmethacrylate. In Toxicology and Hygiene of High Molecular Compounds and Chemical Sources Used for Their Synthesis, pp. 151–178. Moscow: Nauka, 1966.
9. Paulet, G., S. Desbrousses, and P. Toulouse: Toxicologie du methacrylate de methyl. Evolution de la concentration dans le sang chez le lapin et le chien in vivo. Arch. Malad. Prof. 4,5:604–611 (1979).
10. Crout, D., J.A. Corkill, M.L. James, et al. Methyl methacrylate metabolism in man. The hydrolysis of methylmethacrylate to methacrylic acid during total hip replacement. Clin. Orthopaed. Related Res. 141: 90–95 (1979).
11. Bereznowski, Z.: In vivo assessment of methacrylate metabolism and toxicity. Int. J. Biochem. Cell. Biol. 27:1311–1316 (1995).
12. Popov, T., Z. Zaprjanov, I. Benchev, et al.: Methanol. In Atlas of Toxicokinetics, pp 127–128. Sofia, Bulgaria: MF, 1984.
13. Bereznowski, Z.: Methacrylate uptake by isolated hepatocytes and perfused rat liver. Int. J. Biochem. Cell. Biol. 29:675–679 (1994).
14. Crout, D., E. Lloyd, and J. Singh: Metabolism of methyl methacrylate: Evidence for metabolism by the valine pathway of catabolism in rat and man. Xenbiotica 12:821–829 (1982).
15. Murray, R.K., D.K. Granner, P.A. Mayes, and V. W. Rodwell: Harper’s Biochemistry, 25th ed. Stamford, Conn.: Appleton & Lange, 2000.
16. Bulgarian National Standard (BNSA): Harmful Compounds in Working Media Air. Sampling, Analysis and Evaluation (BNS 12 430–74). Sofia, Bulgaria: MF, 1975.
17. Bulgarian National Standard (BNS): Harmful Compounds and TLV (BNS 16 608–87). Sofia, Bulgaria: MF, 1987.
18. Kovalenko, A.L., S.A. Getta, and T.A. Manukian: Reconstruction of production of souvenirs by cold polymerisation of methylmethacrylate as an important means in providing healthier working conditions. Med. Tr. Prom. Ekol. 1:31–33 (1995).
19. Nachev, N.: Acid-base status. In Physiology, pp. 292–307. Sofia, Bulgaria: MF, 1985.
20. Charakchiev, D.: Acid-base status and blood gases in occupational diseases with toxic and chemical ethyology. In D. Charakchiev, ed., Blood Gases and Acid-Base Status of the Organism in Occupational Diseases, pp. 182–204. Sofia, Bulgaria: MF, 1983.
21. Monov, A.: Intoxication with methanol. In A. Monov, ed., Clinical Toxicology, pp. 346–351. Sofia, Bulgaria: MF, 1981.
22. Jedrychowski, W.A.: Styrene and methyl methacrylate in the industrial environment as a risk factor of chronic obstructive lung disease. Int. Arch. Occup. Environ. Health 51:151–157 (1982).
23. Prakova, G., and L. Mikhov: Respiratory system functional status in workers professionally exposed to methylmethacrylate (MMA). Hyg. Public Health 2:21–24 (1995).
24. Kirjakov, K.: Acetone cyanhydrine. In Occupational Diseases, vol. I, pp. 448–450. Sofia, Bulgaria: MF, 1976.
25. Mizunuma, K., T. Kawai, T. Yasagui, et al.: Biological monitoring and possible health effects in workers occupationally exposed to methyl methacrylate. Int. Arch. Occup. Environ. Health 65:227–232 (1993).
26. Prakova, G.: Occupational and Health Problems of Workers from Production and Processing of Methyl Methacrylate. PhD diss., Thracian University, Stara Zagora, Bulgaria, 1999.
27. Cromer, J., and K.A. Kronover: Study of Methyl Methacrylate Exposures and Employee Health (DHEW [NIOSH] 77–119). Cincinnati, Ohio: National Institute for Occupational Safety and Health, 1976.