Remifentanil produces vasorelaxation in isolated rat thoracic aorta strips

Acta Anaesthesiologica Scandinavica

Volumn 47, Issue 1, 2003, Pages 65-69

  Ünlügenç, Hakki ^a   Itegin, M ^a   Ocal I ^a   Ozalevli M ^a   Guler T ^a   Isik, G ^a  

^a CUKUROVA UNIVERSITY   (Turkey)

Author keywords

Analgesic; Arteries; Endothelium; Relaxation; Remifentanil; Smooth muscle; Vasodilation

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; INDOMETACIN; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHLORIDE; REMIFENTANIL;

ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; THORACIC AORTA; VASCULAR RING; VASODILATATION;

ACETYLCHOLINE; ANALGESICS, OPIOID; ANIMALS; AORTA, THORACIC; CALCIUM CHANNEL BLOCKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; EPOPROSTENOL; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; PHENYLEPHRINE; PIPERIDINES; POTASSIUM CHLORIDE; RATS; RATS, WISTAR; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0037223788     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-6576.2003.470111.x     Document Type: Article

References (21)

1. Elliott PO, -Hare R, Bill KM et al. Severe cardiovascular depression with remifentanil. Anesth Analg 2000: 91: 58-61.
2. Sebel PS, Hoke JF, Westmorland C et al. Histamine concentrations and hemodynamic responses after remifentanil. Anesth Analg 1995: 80: 990-993.
3. Chang KSK, Feng MD, Davis RF. Midazolam produces vasodilation by mixed endothelium-dependent and - Independent mechanism. Anesth Analg 1994: 78: 710-717.
4. Gelb AW, Zhang C, Hamilton JT. Propofol induces dilation and inhibits constriction in guinea pig basilar arteries. Anesth Analg 1996: 83: 472-476.
5. Godfraind T, Kaba A. Blockade or reversal of the contraction induced by calcium and adrenaline in depolarized arterial smooth muscle. Br J Pharmacol 1969: 36: 549-560.
6. Rinaldi GJ, Cingolani HE. Effect of diabetes on fast response to norepinephrine in rat aorta. Diabetes 1992: 41: 30-34.
7. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980: 288: 373-376.
8. Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987: 327: 524-526.
9. Moncada S, Gryglewski R, Bunting S, Vane JR. An enzyme isolated from arteries transforms prostoglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 1976: 263: 663-665.
10. Palmer RMJ, Rees DD, Ashton DS, Moncada S. L-Arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun 1988: 153: 1251-1256.
11. Fleckenstein A. Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. Annu Rev Pharmacol Toxicol 1977: 17: 149-166.
12. Bolton TB. Mechanisms of action of transmitters and other substances on smooth muscle. Physiol Rev 1979: 59: 606-718.
13. Godfraind T, Miller R, Wibo M. Calcium antagonism and calcium entry blockade. Pharmacol Rev 1986: 38: 321-416.
14. Atechson R, Lambert DG. Update on opioid receptors. Br J Anaesth 1994: 73: 132-134.
15. Yaksh TL. The postinjury state. Curr Opin Neurol Neurosurg 1993: 6: 250-256.
16. Bürkle H, Dunbar S, Aken HV. Remifentanil: A novel, short-acting, μ-opioid. Anesth Analg 1996: 83: 646-651.
17. White DA, Reitan JA, Kien ND, Thorup SJ. Decrease in vascular resistance in the isolated canine hindlimb after graded doses of alfentanil, fentanyl, and sufentanil. Anesth Analg 1990: 71: 29-34.
18. Bailey PL. Narcotic intravenous anesthetics. In: Miller RD, ed. Anesthesia, 3rd Edn. Place: Churchill Livingstone Inc, New York 1990: 281-366.
19. Starck T, Hall D, Freas W et al. Peripheral vascular depression with sufentanil in the dog. Anesth Analg 1989: 68: S277.
20. O'Keefe R, Domalik -Wawrzynski L, Guerrero JL, Rosow CE, Lowenstein E, Powell WJ. Local and neurally mediated effects of sufentanil on canine skeletal muscle vascular resistance. J Pharmacol Exp Ther 1987: 242: 699-706.
21. Lowenstein E, Whiting RB, Bittar DA, Sanders CA Powell WJ. Local and neurally mediated effects of morphine on skeletal muscle vascular resistance. J Pharmacol Exp Ther 1972: 180: 359-367.