Amyloid β protein enhances the clearance of extracellular L-glutamate by cultured rat cortical astrocytes

Neuroscience Research

Volumn 45, Issue 1, 2003, Pages 25-31

  Abe, Kazuho ^a   Misawa, Miwa ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Amyloid protein; Astrocyte; Culture; Glutamate; Glutamate transporter

Indexed keywords

AMYLOID BETA PROTEIN; ANTIOXIDANT; CATALASE; GALLIC ACID PROPYL ESTER; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; TROLOX C;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL CULTURE; CONTROLLED STUDY; INCUBATION TIME; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TIME; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMINO ACID TRANSPORT SYSTEM X-AG; AMYLOID BETA-PROTEIN; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; ASTROCYTES; BLOTTING, WESTERN; CELLS, CULTURED; CEREBRAL CORTEX; EXTRACELLULAR SPACE; GLUTAMIC ACID; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0037223547     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(02)00190-6     Document Type: Article

References (37)

1. Abe K., Abe Y., Saito H. Evaluation of L-glutamate clearance capacity of cultured rat cortical astrocytes. Biol. Pharm. Bull. 23:2000;204-207.
2. Abe K., Kato M., Saito H. Human amylin mimics amyloid β protein-induced reactive gliosis and inhibition of cellular redox activity in cultured astrocytes. Brain Res. 762:1997;285-288.
3. 2+-dependent late phase. J. Neurochem. 67:1996;2074-2078.
4. Abe K., Matsuki N. Measurement of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction activity and lactate dehydrogenase release using MTT. Neurosci. Res. 38:2000;325-329.
5. Abe K., Saito H. Adenosine stimulates stellation of cultured rat cortical astrocytes. Brain Res. 804:1998;63-71.
6. Abe K., Saito H. Amyloid β protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes. Neurosci. Res. 31:1998;295-305.
7. Abe K., Saito H. Both oxidative stress-dependent and independent effects of amyloid β protein are detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assay. Brain Res. 830:1999;146-154.
8. Abe K., Saito H. L-Glutamate suppresses amyloid β protein-induced stellation of cultured rat cortical astrocytes. J. Neurochem. 74:2000;280-286.
9. Bales K.R., Du Y., Dodel R.C., Yan G.M., Hamilton-Byrd E., Paul S.M. The NF-κB/Rel family of proteins mediates Aβ-induced neurotoxicity and glial activation. Mol. Brain Res. 57:1998;63-72.
10. Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid β protein toxicity. Cell. 77:1994;817-827.
11. Burdick D., Soregham B., Kwon M., Kosmoski J., Knauer M., Henschen A., Yates J., Cotman C., Glabe C. Assembly and aggregation properties of synthetic Alzheimer's A4/β amyloid peptide analogs. J. Biol. Chem. 267:1992;546-554.
12. Canning D.R., McKeon R.J., DeWitt D.A., Perry G., Wujek J.R., Frederickson R.C.A., Silver J. β-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal growth. Exp. Neurol. 124:1993;289-298.
13. Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-634.
14. Dickson D.W., Farlo J., Davies P., Crystal H., Fuld P., Yen S.C. A double-labeling immunohistochemical study of senile plaques. Am. J. Pathol. 132:1988;86-101.
15. Duffy P.E., Rapport M., Graf L. Glial fibrillary acidic protein and Alzheimer-type senile dimentia. Neurology. 30:1990;778-782.
16. Funato H., Yoshimura M., Yamazaki T., Saido T.C., Ito Y., Yokofujita J., Okeda R., Ihara Y. Astrocytes containing amyloid β-protein (Aβ)-positive granules are associated with Ab40-positive diffuse plaques in the aged human brain. Am. J. Pathol. 152:1998;983-992.
17. +-dependent glutamate uptake in rat hippocampal astrocyte cultures. J. Neurochem. 67:1996;277-286.
18. Hu J., Akama K.T., Kraft G.A., Chromy B.A., Van Eldik L.J. Amyloid-β peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release. Brain Res. 785:1998;195-206.
19. Kato M., Saito H., Abe K. Nanomolar amyloid β protein-induced inhibition of cellular redox activity in cultured astrocytes. J. Neurochem. 68:1997;1889-1895.
20. Koh J.Y., Yang L.L., Cotman C.W. β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. 533:1990;315-320.
21. Mandybur T.I., Chuirazzi C.C. Astrocytes and the plaques of Alzheimer's disease. Neurology. 40:1990;635-639.
22. Mattson M.P., Cheng B., Davis D., Bryant K., Lieberburg I., Rydel R.E. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12:1992;376-389.
23. Mattson M.P., Tomaselli K.J., Rydel R.E. Calcium-destabilization and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF. Brain Res. 621:1993;35-49.
24. Parpura-Gill A., Beitz D., Uemura E. The inhibitory effects of β-amyloid on glutamate and glucose uptakes by cultured astrocytes. Brain Res. 754:1997;65-71.
25. Patel A.J., Gunasekera S., Jen A., Rohande Silva H.A. β-Amyloid-mediated inhibition of redox activity (MTT reduction) is not an indicator of astroglial degeneration. Neuroreport. 7:1996;2026-2030.
26. Pike C.J., Walencewicz A.J., Glabe C.G., Cotman C.W. In vivo aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563:1991;311-314.
27. Pike C.J., Cummings B.J., Monzavi R., Cotman C.W. β-Amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease. Neuroscience. 63:1994;517-531.
28. Pines G., Danbolt N.C., Bjoras M., Zhang Y., Bendahan A., Eide L., Koepsell H., Storm-Mathisen J., Seeberg E., Kanner B.I. Cloning and expression of a rat brain L-glutamate transporter. Nature. 360:1992;464-467.
29. Rothman S.M., Olney J.W. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 19:1986;105-111.
30. +-dependent glutamate transporters by cyclic AMP analogs and neurons. Mol. Pharmacol. 53:1998;355-369.
31. Schwarcz R., Foster A.C., French E.D., Whetsell W.O., Kohler C. Excitotoxic models for neurodegenerative disorders. Life Sci. 35:1984;19-32.
32. +-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. USA. 89:1992;10955-10959.
33. Swanson R.A., Liu J., Miller J.W., Rothstein J.D., Farrel K., Stein B.A., Longuemare M.C. Neuronal regulation of glutamate transporter subtype expression in astrocytes. J. Neurosci. 17:1997;932-940.
34. Tanaka K. Expression cloning of a rat glutamate transporter. Neurosci. Res. 16:1993;149-153.
35. Terzi E., Holzemenn G., Seeling J. Reversible random coil-β sheet transition of the Alzheimer β-amyloid fragment (25-35). Biochemistry. 33:1994;1345-1350.
36. Yamaguchi H., Sugihara S., Ogawa A., Saito T.C., Ihara Y. Diffuse plaques associated with astroglial amyloid β protein, possibly showing a disappearing stage of senile plaques. Acta Neuropathol. (Berl). 95:1998;217-222.
37. Yankner B.A., Duffy L.K., Kirschner D.A. Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science. 25:1990;279-282.