Baculovirus vectors: Novel mammalian cell gene-delivery vehicles and their applications

American Journal of PharmacoGenomics

Volumn 3, Issue 1, 2003, Pages 53-63

  Hüser, Andreas ^a   Hofmann, Christian ^a  

^a DeveloGen AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GENE PRODUCT; MONOCLONAL ANTIBODY; PROTEIN P53; RECOMBINANT PROTEIN; VACCINE; VIRUS VECTOR;

BACULOVIRUS; DNA SEQUENCE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; IMMUNE RESPONSE; MAMMAL CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RAT; RECOMBINANT GENE; REVIEW; TECHNOLOGY; VIRAL GENE DELIVERY SYSTEM; VIRUS INFECTION;

ANIMALS; BACULOVIRIDAE; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; GENE THERAPY; GENETIC VECTORS; HUMANS;

INSECTA; MAMMALIA; UNIDENTIFIED BACULOVIRUS;

EID: 0037221944     PISSN: 11752203     EISSN: None     Source Type: Journal    
DOI: 10.2165/00129785-200303010-00007     Document Type: Review

References (79)

1. Ayres MD, Howard SC, Kuzio J, et al. The complete DNA sequence of Autographa californica nuclear polyhedrosis virus. Virology 1994; 202: 586-605
2. Berghold GH. Die Isolierung des Polyedervirus und die Natur der Polyeder. Z Naturforsch [B] 1947; 2b: 122-43
3. Smith GE, Summers MD, Fraser MJ. Production of human beta interferon in insect cells infected with a baculovirus expression vector. Mol Cell Biol 1983; 3: 2156-65
4. Hofmann C, Sandig V, Jennings G, et al. Efficient gene transfer into human hepatocytes by baculovirus vectors. Proc Natl Acad Sci U S A 1995; 92: 10099-103
5. Monsma SA, Blissard GW. Identification of a membrane fusion domain and an oligomerization domain in the baculovirus GP64 envelope fusion protein. J Virol 1995; 69: 2583-95
6. Miller LK. Baculoviruses: high-level expression in insect cells. Curr Opin Genet Dev 1993; 3: 97-101
7. Cory JS, Bishop DH. Use of baculoviruses as biological insecticides. Mol Biotechnol 1997; 7: 303-13
8. Vaughn JL, Goodwin RH, Tompkins GJ, et al. The establishment of two cell lines from the insect Spodoptera frugiperda (Lepidoptera; Noctuidae). In Vitro 1977; 13: 213-7
9. Altmann F, Staudacher E, Wilson IB, et al. Insect cells as hosts for the expression of recombinant glycoproteins. Glycoconj J 1999; 16: 109-23
10. Luckow VA, Lee SC, Barry GF, et al. Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli. J Virol 1993; 67: 4566-79
11. Kitts PA, Possee RD. A method for producing recombinant baculovirus expression vectors at high frequency. Biotechniques 1993; 14: 810-7
12. Patterson RM, Selkirk JK, Merrick BA. Baculovirus and insect cell gene expression: review of baculovirus biotechnology. Environ Health Perspect 1995; 103: 756-9
13. Doller G, Reimann R, Groner A. Baculovirus proteins binding to human immunoglobulins without neutralizing activity. Naturwissenschaften 1983; 70: 370-1
14. Tjia ST, zu Altenschildesche GM, Doerfler W. Autographa californica nuclear polyhedrosis virus (AcNPV) DNA does not persist in mass cultures of mammalian cells. Virology 1983; 125: 107-17
15. Carbonell LF, Miller LK. Baculovirus interaction with nontarget organisms: a virus-borne reporter gene is not expressed in two mammalian cell lines. Appl Environ Microbiol 1987; 53: 1412-7
16. Carbonell LF, Klowden MJ, Miller LK. Baculovirus-mediated expression of bacterial genes in dipteran and mammalian cells. J Virol 1985; 56: 153-60
17. Hartig PC, Chapman MA, Hatch GG, et al. Insect virus: assays for toxic effects and transformation potential in mammalian cells. Appl Environ Microbiol 1989; 55: 1916-20
18. Hartig PC, Cardon MC, Kawanishi CY. Insect virus: assays for viral replication and persistence in mammalian cells. J Virol Methods 1991; 31: 335-44
19. Boyce FM, Bucher NL. Baculovirus-mediated gene transfer into mammalian cells. Proc Natl Acad Sci U S A 1996; 93: 2348-52
20. Duisit G, Saleun S, Douthe S, et al. Baculovirus vector requires electrostatic interactions including heparan sulfate for efficient gene transfer in mammalian cells. J Gene Med 1999; 1: 93-102
21. Tani H, Nishijima M, Ushijima H, et al. Characterization of cell-surface determinants important for baculovirus infection. Virology 2001; 279: 343-53
22. Volkman LE, Goldsmith PA. Mechanism of neutralization of budded Autographa californica nuclear polyhedrosis virus by a monoclonal antibody: inhibition of entry by adsorptive endocytosis. Virol 1985; 143: 185-95
23. Hofmann C, Lehnert W, Strauss M. The baculovirus vector system for gene delivery into hepatocytes. Gene Ther Mol Biol 1998; 1: 231-9
24. Charlton CA, Volkman LE. Penetration of Autographa californica nuclear polyhedrosis virus nucleocapsids into IPLB Sf 21 cells induces actin cable formation. Virology 1993; 197: 245-54
25. van Loo ND, Fortunati E, Ehlert E, et al. Baculovirus infection of nondividing mammalian cells: mechanisms of entry and nuclear transport of capsids. J Virol 2001; 75: 961-70
26. Shoji I, Aizaki H, Tani H, et al. Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors. J Gen Virol 1997; 78: 2657-64
27. Park SW, Lee HK, Kim TG, et al. Hepatocyte-specific gene expression by baculovirus pseudotyped with vesicular stomatitis virus envelope glycoprotein. Biochem Biophys Res Commun 2001; 289: 444-50
28. Condreay JP, Witherspoon SM, Clay WC, et al. Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector. Proc Natl Acad Sci U S A 1999; 96: 127-32
29. Sarkis C, Serguera C, Petres S, et al. Efficient transduction of neural cells in vitro and in vivo by a baculovirus-derived vector. Proc Natl Acad Sci U S A 2000; 97: 14638-43
30. Chen WY, Bailey EC, McCune SL, et al. Reactivation of silenced, vitally transduced genes by inhibitors ofhistone deacetylase. Proc Natl Acad Sci U S A 1997; 94: 5798-803
31. Hüser A. Hüllmodifiziertes Bakulovirus Autographa californica als Gentransfervektor in vitro und in vivo [dissertation]. Berlin: Humboldt University, 2001
32. Barsoum J, Brown R, McKee M, et al. Efficient transduction of mammalian cells by a recombinant baculovirus having the vesicular stomatitis virus G glycoprotein. Hum Gene Ther 1997; 8: 2011-8
33. Mangor JT, Monsma SA, Johnson MC, et al. A GP64-null baculovirus pseudotyped with vesicular stomatitis virus G protein. J Virol 2001; 75: 2544-56
34. Boublik Y, Di Bonito P, Jones IM. Eukaryotic virus display: engineering the major surface glycoprotein of the Autographa californica nuclear polyhedrosis virus (AcNPV) for the presentation of foreign proteins on the virus surface. Biotechnology (N Y) 1995; 13: 1079-84
35. Grabherr R, Ernst W, Doblhoff-Dier O, et al. Expression of foreign proteins on the surface of Autographa californica nuclear polyhedrosis virus. Biotechniques 1997; 22: 730-5
36. Mottershead D, van der Linden I, von Bonsdorff CH, et al. Baculoviral display of the green fluorescent protein and rubella virus envelope proteins. Biochem Biophys Res Commun 1997; 238: 717-22
37. Lindley KM, Su JL, Hodges PK, et al. Production of monoclonal antibodies using recombinant baculovirus displaying gp64-fusion proteins. J Immunol Methods 2000; 234: 123-35
38. Mottershead DG, Alfthan K, Ojala K, et al. Baculoviral display of functional scFv and synthetic IgG-binding domains. Biochem Biophys Res Commun 2000; 275: 84-90
39. Grabherr R, Ernst W, Oker-Blom C, et al. Developments in the use of baculoviruses for the surface display of complex eukaryotic proteins. Trends Biotechnol 2001; 19: 231-6
40. Harris JD, Lemoine NR. Strategies for targeted gene therapy. Trends Genet 1996; 12: 400-5
41. Hüser A, Rudolph M, Hofmann C. Incorporation of decay-accelerating factor into the baculovirus envelope generates complement-resistant gene transfer vectors. Nat Biotechnol 2001; 19: 451-5
42. Gao R, McCormick CJ, Arthur MJ, et al. High efficiency gene transfer into cultured primary rat and human hepatic stellate cells using baculovirus vectors. Liver 2002; 22: 15-22
43. Ma L, Tamarina N, Wang Y, et al. Baculovirus-mediated gene transfer into pancreatic islet cells. Diabetes 2000; 49: 1986-91
44. Kronschnabl M, Marschall M, Stamminger T. Efficient and tightly regulated expression systems for the human cytomegalovirus major transactivator protein IE2p86 in permissive cells. Virus Res 2002; 83: 89-102
45. Condreay JP. Application of recombinant baculoviruses to mammalian cell-based assay development [abstract]. 5th Gene Delivery and Cellular Protein Expression Conference; 2001 Sep 9-13, Semmering, Austria
46. Yap CC, Ishii K, Aoki Y, et al. A hybrid baculovirus-T7 RNA polymerase system for recovery of an infectious virus from cDNA. Virology 1997; 231: 192-200
47. Delaney WEI, Edwards R, Colledge D, et al. Cross-resistance testing of antihepadnaviral compounds using novel recombinant baculoviruses which encode drug-resistant strains of hepatitis B virus. Antimicrob Agents Chemother 2001; 45: 1705-13
48. Delaney WE, Isom HC. Hepatitis B virus replication in human HepG2 cells mediated by hepatitis B virus recombinant baculovirus. Hepatology 1998; 28: 1134-46
49. Delaney WE, Miller TG, Isom HC. Use of the hepatitis B virus recombinant baculovirus-HepG2 system to study the effects of (-)-beta-2′,3′-dideoxy-3′-thiacytidine on replication of hepatitis B virus and accumulation of covalently closed circular DNA. Antimicrob Agents Chemother 1999; 43: 2017-26
50. Yap CC, Ishii K, Aizaki H, et al. Expression of target genes by coinfection with replication-deficient viral vectors. J Gen Virol 1998; 79: 1879-88
51. Fipaldini C, Bellei B, La Monica N. Expression of hepatitis C virus cDNA in human hepatoma cell line mediated by a hybrid baculovirus-HCV vector. Virology 1999; 255: 302-11
52. McCormick CJ, Rowlands DJ, Harris M. Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors. J Gen Virol 2002; 83: 383-94
53. Hagglund R, Munger J, Poon AP, et al. U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner. J Virol 2002; 76: 743-54
54. Ye GJ, Roizman B. The essential protein encoded by the UL31 gene of herpes simplex virus 1 depends for its stability on the presence of UL34 protein. Proc Natl Acad Sci U S A 2000; 97: 11002-7
55. Ye GJ, Vaughan KT, Vallee RB, et al. The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol 2000; 74: 1355-63
56. Zhou G, Galvan V, Campadelli-Fiume G, et al. Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins. J Virol 2000; 74: 11782-91
57. Munger J, Roizman B. The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins. Proc Natl Acad Sci U S A 2001; 98: 10410-5
58. Munger J, Chee AV, Roizman B. The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage. J Virol 2001; 75: 5491-7
59. Lopez P, Van Sant C, Roizman B. Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1. J Virol 2001; 75: 3832-40
60. Sciortino MT, Taddeo B, Poon AP, et al. Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection. Proc Natl Acad Sci U S A 2002; 99: 8318-23
61. Dwarakanath RS, Clark CL, McElroy AK, et al. The use of recombinant baculoviruses for sustained expression of human cytomegalovirus immediate early proteins in fibroblasts. Virology 2001; 284: 297-307
62. Cheshenko N, Krougliak N, Eisensmith RC, et al. A novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus. Gene Ther 2001; 8: 846-54
63. Sollerbrant K, Elmen J, Wahlestedt C, et al. A novel method using baculovirus-mediated gene transfer for production of recombinant adeno-associated virus vectors. J Gen Virol 2001; 82: 2051-60
64. Palombo F, Monciotti A, Recchia A, et al. Site-specific integration in mammalian cells mediated by a new hybrid baculovirus-adeno-associated virus vector. J Virol 1998; 72: 5025-34
65. Kost TA, Klein JL, Condreay JP. Application of recombinant baculoviruses in biopharmaceutical research. In: Al-Rubeai M, editor. Cell engineering. Dordrecht: Kluwer Academic Publishers, 2000: 1-28
66. Merrihew RV, Clay WC, Condreay JP, et al. Chromosomal integration of transduced recombinant baculovirus DNA in mammalian cells. J Virol 2001; 75: 903-9
67. Sandig V, Hofmann C, Steinert S, et al. Gene transfer into hepatocytes and human liver tissue by baculovirus vectors. Hum Gene Ther 1996; 7: 1937-45
68. Hofmann C, Strauss M. Baculovirus-mediated gene transfer in the presence of human serum or blood facilitated by inhibition of the complement system. Gene Ther 1998; 5: 531-6
69. Hofmann C, Hüser A, Lehnert W, et al. Protection of baculovirus-vectors against complement-mediated inactivation by recombinant soluble complement receptor type 1. Biol Chem 1999; 380: 393-5
70. Gronowski AM, Hilbert DM, Sheehan KC, et al. Baculovirus stimulates antiviral effects in mammalian cells. J Virol 1999; 73: 9944-51
71. Beck NB, Sidhu JS, Omiecinski CJ. Baculovirus vectors repress phenobarbital-mediated gene induction and stimulate cytokine expression in primary cultures of rat hepatocytes. Gene Ther 2000; 7: 1274-83
72. Bilello JP, Delaney WE, Boyce FM, et al. Transient disruption of intercellular junctions enables baculovirus entry into nondividing hepatocytes. J Virol 2001; 75: 9857-71
73. Hoare JM, Waddington SN, Khan S, et al. Soluble complement receptor 1(SCR1) rescues mice from fatal toxicity following intra-portal administration of baculovirus vectors [abstract]. Mol Ther 2002; 5: S152
74. Kircheis R, Wightman L, Schreiber A, et al. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 2001; 8: 28-40
75. Airenne KJ, Hiltunen MO, Turunen MP, et al. Baculovirus-mediated periadventitial gene transfer to rabbit carotid artery. Gene Ther 2000; 7: 1499-504
76. Haeseleer F, Imanishi Y, Saperstein DA, et al. Gene transfer mediated by recombinant baculovirus into mouse eye. Invest Ophthalmol Vis Sci 2001; 42: 3294-300
77. Aoki H, Sakoda Y, Jukuroki K, et al. Induction of antibodies in mice by a recombinant baculovirus expressing pseudorabies virus glycoprotein B in mammalian cells. Vet Microbiol 1999; 68: 197-207
78. Pieroni L, Maione D, La Monica N. In vivo gene transfer in mouse skeletal muscle mediated by baculovirus vectors. Hum Gene Ther 2001; 12: 871-81
79. Song SU, Boyce FM. Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin). Exp Mol Med 2001; 33: 46-53