Thrombus precursor protein, endogenous thrombin potential, von-Willebrand factor and activated factor VII in suspected deep vein thrombosis: Is there a place for new parameters?

British Journal of Haematology

Volumn 120, Issue 1, 2003, Pages 123-128

  Bucek, Robert A ^a   Reiter, Markus ^a   Quehenberger, Peter ^a   Weltermann, Ansgar ^a   Kyrle, Paul A ^a   Minar, Erich ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Activated factor VII; Deep vein thrombosis; Endogenous thrombin potential; Thrombus precursor protein; von Willebrand factor

Indexed keywords

BLOOD CLOTTING FACTOR 7; D DIMER; PROTEIN PRECURSOR; PROTHROMBIN COMPLEX; THROMBIN; THROMBIN ANTITHROMBIN COMPLEX; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; BLOOD COMPONENT; CONTROLLED STUDY; CORRELATION ANALYSIS; DEEP VEIN THROMBOSIS; DIAGNOSTIC ACCURACY; DISEASE COURSE; ECHOGRAPHY; EVALUATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PARAMETER; PHLEBOGRAPHY; PRIORITY JOURNAL; SYMPTOMATOLOGY;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BLOOD COAGULATION FACTORS; FACTOR VIIA; FEMALE; FIBRIN; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; ROC CURVE; SENSITIVITY AND SPECIFICITY; THROMBIN; VENOUS THROMBOSIS; VON WILLEBRAND FACTOR;

EID: 0037219745     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.03984.x     Document Type: Article

References (29)

1. Aschwanden, M., Labs, K.H., Jeannerer, C., Gehrig, A. & Jaeger, K.A. (1999) The value of rapid D-Dimer testing combined with structured clinical evaluation for the diagnosis of deep vein thrombosis. Journal of Vascular Surgery, 30, 929-935.
2. Baxter, G.M., McKechnie, S. & Duffy, P. (1990) Colour doppler ultrasound in deep venous thrombosis: A comparison with venography. Clinical Radiology, 42, 32-36.
3. Becker, D.M., Philbrick, J.T., Bachhuber, T.L. & Humphries, J.E. (1996) D-Dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? Archives of Internal Medicine, 156, 939-946.
4. Boneu, B., Bes, G., Pelzer, H., Sie, P. & Boccalon, H. (1991) D-Dimers, thrombin antithombin III complexes and prothrombin fragments 1+2: Diagnostic value in clinically suspected deep vein thrombosis. Thrombosis and Haemostasis, 65, 28-32.
5. Bounameaux, H., de Moerloose, P., Perrier, A. & Reber, G. (1994) Plasma measurement of D-Dimer as diagnostic aid in suspected venous thromboembolism: An overview. Thrombosis and Haemostasis, 71, 1-6.
6. Bucek, R.A., Koca, N., Reiter, M., Haumer, M., Zontsich, T. & Minar, E. (2002) Algorithms for the diagnosis of deep vein thrombosis in patients with low clinical pre-test probability. Thrombosis Research, 105, 43-47.
7. Bucek, R.A., Kos, T., Schober, E., Zontsich, T., Haumer, M., Pötzi, C. & Minar, E. (2001) Ultrasound with Levovist™ in suspected calf vein thrombosis. Ultrasound in Medicine and Biology, 27, 455-460.
8. Carville, D.G.M., Dimitrijevic, N., Walsh, M., Digirolamo, T., Brill, E.M., Drew, N. & Cargan, P.E. (1996) Thrombus precursor protein (TpP™): Marker of thrombosis early in the pathogenesis of myocardial infarction. Clinical Chemistry, 42, 1537-1541.
9. Douglas, M.G. & Sumner, D.S. (1996) Duplex scanning for deep vein thrombosis: Has it replaced both phlebography and non-invasive testing? Seminars in Vascular Surgery, 9, 3-12.
10. Heijboer, J., Ginsberg, J.S., Büller, H.R., Lensing, A.W.A., Colly, L.P. & ten Cate, J.W. (1992) The use of the D-Dimer test in combination with non-invasive testing versus serial non-invasive testing alone for the diagnosis of deep vein thrombosis. Thrombosis and Haemostasis, 67, 510-513.
11. Hemker, H.C. & Beguin, S. (1995) Thrombin generation in plasma: Its assessment via the endogenous thrombin potential. Thrombosis and Haemostasis, 74, 134-138.
12. Janssen, M.C.H., Heebels, A.E., de-Metz, M., Verbruggen, H., Wollersheim, H., Janssen, S., Schuurmans, M.M. & Novakova, T.R. (1997a) Reliability of five rapid D-Dimer assays compared to ELISA in the exclusion of deep venous thrombosis. Thrombosis and Haemostasis, 77, 262-266.
13. Janssen, M.C.H., Verbruggen, B.W., ter Hark, P.J.C. & Novakova, I.R.O. (1997b) Factor VIIa determination compared to D-Dimer in diagnosis of deep venous thrombosis. Thrombosis Research, 86, 423-426.
14. Kadayifcilar, S., Özatli, D., Özcebe, O.I. & Sener, E.C. (2001) Is activated factor VII associated with retinal vein occlusion? British Journal of Ophthalmology, 85, 1174-1178.
15. Kahn, S.R. (1998) The clinical diagnosis of deep venous thrombosis. Integrating incidence, risk factors, and symptoms and signs. Archives of Internal Medicine, 158, 2315-2323.
16. Kher, A., Diere, R.A., Hemker, H.C. & Beguin, S. (1997) Laboratory assessment of antithrombotic therapy: What tests and if so why? Haemostasis, 27, 211-218.
17. Koster, T., Blann, A.D., Briet, E., Vandenboucke, J.P. & Rosendaal, F.R. (1995) Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet, 345, 152-155.
18. LaCapra, S., Arkel, Y.S., Ku, D.H., Gibson, D., Lake, C. & Lam, X. (2000) The use of thrombus precursor protein, D-Dimer, prothrombin fragment 1.2 and thrombin antithombin in the exclusion of proximal deep vein thrombosis and pulmonary embolism. Blood, Coagulation and Fibrinolysis, 11, 371-377.
19. Nilsson, T., Mellbring, C. & Hedner, U. (1986) Relationship between factor XII, von Willebrand factor and postoperative deep vein thrombosis. Acta Chirurgica Scandinavica, 152, 347-349.
20. Nordström, M., Lindblad, B., Bergqvist, D. & Kjellström, T. (1992) A prospective study of the incidence of deep-vein thrombosis within a defined urban population. Journal of Internal Medicine, 232, 155-160.
21. Rose, S.C., Zwiebel, W.J., Nelson, B.D., Priest, D.L., Knighton, R.A., Brown, J.W., Lawrence, P.F., Stults, B.M., Reading, J.C. & Miller, F.J. (1990) Symptomatic lower extremity deep venous thrombosis: Accuracy, limitations, and role of color duplex flow imaging in diagnosis. Radiology, 175, 639-644.
22. Scharrer, I. & Vigh, Z. (1993) Release of von Willebrand factor after venous occlusion: The importance of standardization of venous occlusion tests. Thrombosis and Haemostasis, 67, 880.
23. Speiser, W., Mallek, R., Koppensteiner, R., Stümpflen, A., Kapiotis, S., Minar, E., Ehringer, H. & Lechner, K. (1990) D-Dimer and TAT measurement in patients with deep venous thrombosis. Utility in diagnosis and judgement of anticoagulant treatment effectiveness. Thrombosis and Haemostasis, 64, 196-201.
24. Stead, N.W., Bauer, K.A., Kinney, T.R., Lewis, J.G., Campbell, E.E., Shifman, M.A., Rosenberg, R.D. & Pizzo, S.V. (1983) Venous thrombosis in a family with defective release of vascular plasminogen activator and elevated plasma factor VIII/von Willebrand's factor. The American Journal of Medicine, 74, 33-39.
25. Wells, P.S., Hirsh, J., Anderson, D.R., Lensing, A.W., Foster, G., Kearon, C., Weitz, J., D'Ovidio, R., Cogo, A. & Prandoni, P. (1995) Accuracy of clinical assessment of deep-vein thrombosis. Lancet, 345, 1326-1330.
26. Wells, P.S., Anderson, D.R., Bormanis, J., Guy, F., Mitchell, M., Gray, L., Clement, C., Robinson, K.S. & Lewandowski, B. (1997) Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet, 350, 1795-1798.
27. Wielders, S., Mukherjee, M., Michiels, J., Rijkers, D.T.S., Cambus, J.R., Knebel, R.W.C., Kakkar, V., Hemker, H.C. & Beguin, S. (1997) The routine determination of the endogenous thrombin potential, first results in different forms of hyper- and hypocoagulability. Thrombosis and Haemostasis, 77, 629-636.
28. Wille-Jorgensen, P., Borris, L., Jorgensen, L.N., Hauch, G., Lassen, M.R., Nehen, A.M., Kjaer, L. & Jensen, R. (1992) Phlebography as the gold standard in thromboprophylactic studies? A multi-center interobserver variation study. Acta Radiologica, 33, 24-28.
29. Yamamoto, H., Vreys, I., Stassen, J.M., Yoshimoto, R., Vermylen, J. & Hoylaerts, M.F. (1998) Antagonism of vWF inhibits both injury induced arterial and venous thrombosis in the hamster. Thrombosis and Haemostasis, 79, 202-210.