Identification of differentially expressed genes in brains of newborn Borna disease virus-infected rats in the absence of inflammation

Archives of Virology

Volumn 148, Issue 1, 2003, Pages 45-63

  Jehle, C ^a   Herpfer, I ^a   Rauer, M ^a   Schwemmle, M ^a,b   Sauder, Christian ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ANIMALS, NEWBORN; BETA 2-MICROGLOBULIN; BORNA DISEASE; BORNA DISEASE VIRUS; BRAIN; CHEMOKINES; CHEMOKINES, CXC; FATTY ACIDS; GENE EXPRESSION; HIPPOCAMPUS; INFLAMMATION; KINETICS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGAN CULTURE TECHNIQUES; PROTEIN BINDING; RATS; RATS, INBRED LEW; UP-REGULATION;

ANIMALIA; BORNA DISEASE VIRUS; DNA VIRUSES; EUKARYOTA;

EID: 0037218591     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-002-0906-3     Document Type: Article

References (55)

1. Bilzer T, Stitz L (1994) Immune-mediated brain atrophy. CD8+ T cells contribute to tissue destruction during Borna disease. J Immunol 153: 818-823
2. Birkle DL (1993) Regional and temporal variations in the accumulation of unesterified fatty acids and diacylglycerols in the rat brain during kainic acid induced limbic seizures. Brain Res 613: 115-122
3. Boehm U, Klamp T, Groot M, Howard JC (1997) Cellular responses to interferon-gamma. Annu Rev Immunol 15: 749-795
4. Carbone KM, Trapp BD, Griffin JW, Duchala CS, Narayan O (1989) Astrocytes and Schwann cells are virus-host cells in the nervous system of rats with Borna disease. J Neuropathol Exp Neurol 48: 631-644
5. Carbone KM, Park SW, Rubin SA, Waltrip II, Vogelsang GB (1991) Borna disease: Association with a maturation defect in the cellular immune response. J Virol 65: 6154-6164
6. Cole T, Dickson PW, Esnard F, Averill S, Risbridger GP, Gauthier F, Schreiber G (1989) The cDNA structure and expression analysis of the genes for the cysteine proteinase inhibitor cystatin C and for beta 2-microglobulin in rat brain. Eur J Biochem 186: 35-42
7. Corriveau RA, Huh GS, Shatz CJ (1998) Regulation of class I MHC gene expression in the developing and mature CNS by neural activity. Neuron 21: 505-520
8. de la Torre JC (1994) Molecular biology of Borna disease virus: Prototype of a new group of animal viruses. J Virol 68: 7669-7675
9. Dhib-Jalbut SS, Cowan EP (1993) Direct evidence that interferon-beta mediates enhanced HLA-class I expression in measles virus-infected cells. J Immunol 151: 6248-6258
10. Drew PD, Lonergan M, Goldstein ME, Lampson LA, Ozato K, McFarlin DE (1993) Regulation of MHC class I and beta 2-microglobulin gene expression in human neuronal cells. Factor binding to conserved cis-acting regulatory sequences correlates with expression of the genes. J Immunol 150: 3300-3310
11. Eisenman LM, Brothers R, Tran MH, Kean RB, Dickson GM, Dietzschold B, Hooper DC (1999) Neonatal Borna disease virus infection in the rat causes a loss of Purkinje cells in the cerebellum. J Neurovirol 5: 181-189
12. Feng L, Hatten ME, Heintz N (1994) Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS. Neuron 12: 895-908
13. Frotscher M, Heimrich B (1993) Formation of layer-specific fiber projections to the hippocampus in vitro. Proc Natl Acad Sci USA 90: 10400-10403
14. Gonzalez-Dunia D, Eddleston M, Mackman N, Carbone K, de la Torre JC (1996) Expression of tissue factor is increased in astrocytes within the central nervous system during persistent infection with Borna disease virus. J Virol 70: 5812-5820
15. Gonzalez-Dunia D, Watanabe M, Syan S, Mallory M, Masliah E, de la Torre JC (2000) Synaptic pathology in borna disease virus persistent infection. J Virol 74: 3441-3448
16. Gosztonyi G, Ludwig H (2001) Interactions of viral proteins with neurotransmitter receptors may protect or destroy neurons. Curr Top Microbiol Immunol 253: 121-144
17. Hallensleben W, Schwemmle M, Hausmann J, Stitz L, Volk B, Pagenstecher A, Staeheli P (1998) Borna disease virus-induced neurological disorder in mice: Infection of neonates results in immunopathology. J Virol 72: 4379-4386
18. Hans A, Syan S, Crosio C, Sassone-Corsi P, Brahic M, Gonzalez-Dunia D (2001) Borna disease virus persistent infection activates mitogen-activated protein kinase and blocks neuronal differentiation of pc12 cells. J Biol Chem 276: 7258-7265
19. Hausmann J, Hallensleben W, de la Torre JC, Pagenstecher A, Zimmermann C, Pircher H, Staeheli P (1999) T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein. Proc Natl Acad Sci USA 96: 9769-9774
20. Hirano N, Kao M, Ludwig H (1983) Persistent, tolerant or subacute infection in Borna disease virus-infected rats. J Gen Virol 64: 1521-1530
21. Hornig M, Weissenböck H, Horscroft N, Lipkin WI (1999) An infection-based model of neurodevelopmental damage. Proc Natl Acad Sci USA 96: 12102-12107
22. Horwitz MS, Evans CF, Klier FG, Oldstone MB (1999) Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the central nervous system: Astrocytes fail to express major histocompatibility complex class I and II molecules. Lab Invest 79: 235-242
23. Israel A, Kimura A, Fournier A, Fellous M, Kourilsky P (1986) Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H-2 gene. Nature 322: 743-746
24. Jehle C, Lipkin WI, Staeheli P, Marion RM, Schwemmle M (2000) Authentic Borna disease virus transcripts are spliced less efficiently than cDNA-derived viral RNAs. J Gen Virol 81: 1947-1954
25. Jordan I, Lipkin WI (2001) Borna disease virus. Rev Med Virol 11: 37-57
26. Kao M, Ludwig H, Gosztonyi G (1984) Adaptation of Borna disease virus to the mouse. J Gen Virol 65: 1845-1849
27. Kimura T, Griffin DE (2000) The role of CD8(+) T cells and major histocompatibility complex class I expression in the central nervous system of mice infected with neurovirulent sindbis virus. J Virol 74: 6117-6125
28. Klein MA, Frigg R, Flechsig E, Raeber AJ, Kalinke U, Bluethmann H, Bootz F, Suter M, Zinkernagel RM, Aguzzi A (1997) A crucial role for B cells in neuroinvasive scrapie. Nature 390: 687-690
29. Kreutzberg GW (1996) Microglia: A sensor for pathological events in the CNS. Trends Neurosci 19: 312-318
30. Kurtz A, Zimmer A, Schnutgen F, Bruning G, Spener F, Muller T (1994) The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development. Development 120: 2637-2649
31. Lampson LA (1995) Interpreting MHC class I expression and class I/class II reciprocity in the CNS: Reconciling divergent findings. Microscopy Res Tech 32: 267-285
32. Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, Aguet M (1994) Functional role of type I and type II interferons in antiviral defense. Science 264: 1918-1921
33. Neumann H, Schmidt H, Cavalie A, Jenne D, Wekerle H (1997) Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: Differential regulation by interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha. J Exp Med 185: 305-316
34. Njenga MK, Pease LR, Wettstein P, Mak T, Rodriguez M (1997) Interferon alpha/beta mediates early virus-induced expression of H-2D and H-2K in the central nervous system. Lab Invest 77: 71-84
35. Owada Y, Yoshimoto T, Kondo H (1996) Spatio-temporally differential expression of genes for three members of fatty acid binding proteins in developing and mature rat brains. J Chem Neuroanat 12: 113-122
36. Parnes JR, Robinson RR, Seidman JG (1983) Multiple mRNA species with distinct 3′ termini are transcribed from the beta 2-microglobulin gene. Nature 302: 449-452
37. Pavlovic J, Arzet HA, Hefti HP, Frese M, Rost D, Ernst B, Kolb E, Staeheli P, Haller O (1995) Enhanced virus resistance of transgenic mice expressing the human MxA protein. J Virol 69: 4506-4510
38. Planz O, Bilzer T, Sobbe M, Stitz L (1993) Lysis of major histocompatibility complex class I-bearing cells in Borna disease virus-induced degenerative encephalopathy. J Exp Med 178: 163-174
39. Prosniak M, Hooper DC, Dietzschold B, Koprowski H (2001) Effect of rabies virus infection on gene expression in mouse brain. Proc Natl Acad Sci USA 98: 2758-2763
40. Raivich G, Bohatschek M, Kloss CU, Werner A, Jones LL, Kreutzberg GW (1999) Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 30: 77-105
41. Rott R, Becht H (1995) Natural and experimental Borna disease in animals. In: Koprowski H, Lipkin WI (eds) Borna Disease. Springer, Berlin Heidelberg NewYork Tokyo pp 17-30
42. Sauder C, de la Torre JC (1999) Cytokine expression in the rat central nervous system following perinatal Borna disease virus infection. J Neuroimmunol 96: 29-45
43. Sauder C, Hallensleben W, Pagenstecher A, Schneckenburger S, Biro L, Pertlik D, Hausmann J, Suter M, Staeheli P (2000) Chemokine gene expression in astrocytes of Borna disease virus-infected rats and mice in the absence of inflammation. J Virol 74: 9267-9280
44. Sauder C, Wolfer DP, Lipp HP, Staeheli P, Hausmann J (2001) Learning deficits in mice with persistent Borna disease virus infection of the CNS associated with elevated chemokine expression. Behav Brain Res 120: 189-201
45. Schwemmle M (2001) Borna disease virus infection in psychiatric patients: Are we on the right track? Lancet Infect Dis 1: 46-52
46. Staeheli P, Sauder C, Hausmann J, Ehrensperger F, Schwemmle M (2000) Epidemiology of Borna disease virus. J Gen Virol 81: 2123-2135
47. Staeheli P, Sentandreu M, Pagenstecher A, Hausmann J (2001) Alpha/beta interferon promotes transcription and inhibits replication of borna disease virus in persistently infected cells. J Virol 75: 8216-8223
48. Stitz L, Bilzer T, Planz O (2002) The immunopathogenesis of Borna disease virus infection. Front Biosci 7: 541-555
49. Stoppini L, Buchs PA, Muller D (1991) A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37: 173-182
50. Streit WJ, Walter SA, Pennell NA (1999) Reactive microgliosis. Prog Neurobiol 57: 563-581
51. Veerkamp JH, Zimmerman AW (2001) Fatty acid-binding proteins of nervous tissue. J Mol Neurosci 16: 133-142; discussion 151-157
52. von Rheinbaben F, Stitz L, Rott R (1985) Influence of interferon on persistent infection caused by Borna disease virus in vitro. J Gen Virol 66: 2777-2780
53. Weissenböck H, Hornig M, Hickey WF, Lipkin WI (2000) Microglial activation and neuronal apoptosis in Bornavirus infected neonatal Lewis rats. Brain Pathol 10: 260-272
54. Young JK, Baker JH, Muller T (1996) Immunoreactivity for brain-fatty acid binding protein in gomori- positive astrocytes. Glia 16: 218-226
55. Zocher M, Czub S, Schulte-Mönting J, de la Torre JC, Sauder C (2000) Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection. J Neurovirol 6: 462-477