The effects of aqueous extract of Lavandula angustifolia flowers in glutamate-induced neurotoxicity of cerebellar granular cell culture of rat pups

Journal of Ethnopharmacology

Volumn 84, Issue 1, 2003, Pages 91-94

  Büyükokuroǧlu, Mehmet Emin ^a   Gepdiremen, Akçahan ^a   Hacimüftüoǧlu, Ahmet ^a   Oktay, Münir ^b  

^a ATATURK UNIVERSITY   (Turkey)

^b ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Culture; Glutamate; Lavandula angustifolia; Neuron

Indexed keywords

ANTIOXIDANT; GLUTAMIC ACID; LAVANDULA ANGUSTIFOLIA EXTRACT; NEUROPROTECTIVE AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBELLUM CORTEX; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; FLOWER; GRANULAR CELL; LAVANDULA ANGUSTIFOLIA; LAVENDER; MEDICINAL PLANT; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; RAT;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOWERS; GLUTAMIC ACID; LAVANDULA; NEURONS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0037217452     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(02)00286-6     Document Type: Article

References (23)

1. Baytop T. Therapy with Medicinal Plants in Turkey (Past and Present). 3255:1984;316 Publications of the Istanbul University, Istanbul.
2. Brum L.F., Elisabetsky E., Souza D.O. Effects of linalool on [(3)H]MK801 and [(3)H]musimol binding in mouse cortical membranes. Phytotherapy Research. 15:(5):2001;422-425.
3. Davis P.H. Flora of Turkey. 7:1982;76 Edinburgh University Press, Edinburgh.
4. Elisabetsky E., Marschner J., Souza D.O. Effects of linalool on glutamegic system in the rat cerebral cortex. Neurochemical Research. 20:1995;462-465.
5. Elisabetsky E., Brum L.F., Souza D.O. Anticonvulsant properties of linalool on glutamate-related seizure model. Phytomedicine. 6:(2):1999;107-113.
6. Frandsen A., Schousboe A. Excitatory amino acid mediated cytotoxicity and calcium homeostasis in cultured neurons. Journal of Neurochemistry. 60:1995;1202-1211.
7. Gepdiremen A., Düzenli S., Hacimüftüoǧlu A., Bulucu D., Süleyman H. The effects of melatonin in glutamate-induced neurotoxicity of rat cerebellar granular cell culture. Japanese Journal of Pharmacology. 84:2000;467-469.
8. Gepdiremen A., Düzenli S., Hacimüftüoǧlu A., Süleyman H., Öztaǧ S. The effects of dantrolene alone or combination with nimodipine in glutamate-induced neurotoxicity in cerebellar granular cell cultures of rat pups. Pharmacolgical Research. 43:(3):2001;241-244.
9. Ghelardini C., Galeotti N., Salvatore G., Mazzanti G. Local anaesthetic activity of the essential oil of Lavandula angustifolia. Planta Medica. 65:(8):1999;700-703.
10. Gilani A.H., Aziz N., Khan M.A., Shaheen F., Jabeen Q., Siddiqui B.S., Herzig J.W. Ethnopharmacological evaluation of the anticonvulsant, sedative and antispasmodic activities of Lavandula stoechas L. Journal of Ethnopharmacology. 71:2000;161-167.
11. Hohmann J., Zupko I., Redei D., Csanyi M., Falkay G., Mathe I., Janicsak G. Protective effects of the aerial parts of Salvia officinalis, Melissa officinalis and Lavandula angustifolia and their constituents against enzyme-dependent and enzyme-independent lipid peroxidation. Planta Medica. 65:(6):1999;576-578.
12. Hosseinzadeh H., Ramezani M., Salmani G. Antinociceptive, anti-inflammatory and acute toxicity effects of Zataria multiflora Boiss extract in mice and rats. Journal of Ethnopharmacology. 73:2000;379-385.
13. Kovatcheva A.G., Koleva I.I., Ilieva M., Pavlov A., Mincheva M., Konushlieva M. Antioxidant activity of extract from Lavandula vera MM cell cultures. Food Chemistry. 72:2001;295-300.
14. Lis-Balchin M., Hart S. A preliminary study of the effect of essential oils on skeletal and smooth muscle in vitro. Journal of Ethnopharmacology. 58:1997;183-187.
15. Lis-Balchin M., Hart S. Studies on the mode of action of the essential oil of lavender (Lavandula angustifolia P. Miller). Phytotherapy Research. 13:1999;540-542.
16. 2+ elevation in cerebellar slice: a comparative study with the values found in hippocampal slice. Acta Neuropathologica. 89:1995;2-7.
17. Schulz J.B., Henshaw D.R., Siwek D., Jenkins B.G., Ferrante R.J., Cipolloni P.B., Kowall N.W., Rosen B.R., Beal M.F. Involvement of free radicals in excitotoxicity in vivo. Journal of Neurochemistry. 64:1995;2239-2247.
18. 2+) in hypoxia and ischemia in rat brain in vivo. Journal of General Physiology. 95:1990;837-866.
19. Szekely A.N., Costa E., Grayson D.R. Transcriptinal program coordination by N-methyl-D-aspartate-sensitive glutamate receptor stimulation in primary cultures of cerebellar neurons. Molecular Pharmacology. 38:(5):1990;624-633.
20. Wei H., Perry D.C. Dantrolene is cytoprotective in two models of neuronal cell death. Journal of Neurochemistry. 67:(6):1996;2390-2398.
21. Xu J., Wojcik W.J. Gamma aminobutiric acid B receptor mediated inhibition of adenylate cyclase in cultured cerebellar granular cells: blocked by islet activating protein. Journal of Pharmacology and Experimental Therapeutics. 239:1985;568-573.
22. Yildirim A., Mavi A., Oktay M., Kara A.A., Algur O.F., Bilaloglu V. Comparison of antioxidant and antimicrobial activities of tilia (Tilia argentea Desf ex DC), sage (Salvia triloba L.), and black tea (Camellia sinensis) extracts. Journal of Agriculture Food and Chemistry. 48:(10):2000;5030-5034.
23. Zheng W., Wang S.Y. Antioxidant activity and phenolic compounds in selected herbs. Journal of Agriculture Food Chemistry. 49:(11):2001;5165-5170.