Footstrike is the major cause of hemolysis during running

Journal of Applied Physiology

Volumn 94, Issue 1, 2003, Pages 38-42

  Telford, R D ^a   Sly, G J ^b   Hahn, A G ^c   Cunningham, R B ^b   Bryant, C ^b   Smith, J A ^c  

^a GRIFFITH UNIVERSITY   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^c AUSTRALIAN INSTITUTE OF SPORT   (Australia)

Author keywords

Cycling; Erythrocytes; Haptoglobin; Iron status; Methemoglobin

Indexed keywords

HAPTOGLOBIN; HEMOGLOBIN; METHEMOGLOBIN;

ADULT; ARTICLE; CONTROLLED STUDY; CYCLING; EXERCISE; FOOT; GAIT; HEMOGLOBIN DETERMINATION; HEMOLYSIS; HUMAN; HUMAN EXPERIMENT; MALE; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RUNNING;

EID: 0037216293     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00631.2001     Document Type: Article

References (29)

1. Astrand PO and Rodahl K. Textbook of Work Physiology. New York: McGraw-Hill, 1977, p. 454.
2. Bula B, Ziobro E, and Sutylo Z. Myogenic causes of hemolysis. Phys Ed Sport 2: 33-68, 1966.
3. Clark MR. Senescence of red blood cells: progress and problems. Physiol Rev 68: 503-554, 1988.
4. Colt E and Heyman B. Low ferritin levels in runners. J Sports Med Phys Fitness 24: 13-17, 1984.
5. Davidson RJ. Exertional hemoglobinuria: a case report on three cases with studies on the hemolytic mechanism. J Clin Pathol 17: 536-540, 1964.
6. Deiss A. Iron metabolism in reticuloendothelial cells. Semin Hematol 20: 81-90, 1983.
7. Dressendorfer RH, Wade CE, and Frederick EC. Effect of shoe cushioning on the development of reticulocytosis in distance runners. Am J Sports Med 20: 212-216, 1992.
8. Dufaux B, Hoederath A, Streitberger I, Hollmann W, and Assmann G. Serum ferritin, transferrin, haptoglobin and iron in middle and long distance runners, elite rowers, and professional racing cyclists. Int J Sports Med 2: 43-46, 1981.
9. Eichner ER. Gastrointestinal bleeding in athletes. Phys Sports Med 17: 128-140, 1989.
10. Falsetti JL, Burke ER, Feld RD, Frederick EC, and Ratering C. Hematological variations after endurance running with hard soled and air cushioned shoes. Phys Sports Med 11: 118-127, 1983.
11. Gilligan DR, Altschule MD, and Katersky EM. Physiological intra-vascular hemolysis of exercise: hemoglobinemia and hemoglobinuria following cross-country runs. J Clin Lab Invest 22: 859-869, 1943.
12. Green HJ, Carter S, Grant S, Tupling R, Coates G, and Ali M. Vascular volumes and hematology in male and female runners and cyclists. Eur J Appl Physiol 79: 244-250, 1999.
13. Green HJ, Sutton JR, Coates G, Ali M, and Jones S. Response of red cell and plasma volume to prolonged training in humans. J Appl Physiol 70: 1810-1815, 1991.
14. Hunding A, Jordal R, and Paulev PE. Runner's anemia and iron deficiency. Acta Med Scand 209: 315-318, 1981.
15. Kenward J. A method for comparing profiles of repeated measurements. Appl Stat 36: 296-308, 1987.
16. Mairbaurl H, Humpeler E, Schwaberger G, and Pessenhofer H. Training dependent changes in red blood cell density and erythrocytic oxygen transport. J Appl Physiol 55: 1403-1407, 1983.
17. Mansouri A and Lurie AA. Concise review: methemoglobinemia. Am J Hematol 42: 7-12, 1993.
18. Miller BJ, Pate RR, and Burgess W. Foot impact force and intravascular hemolysis during distance running. Int J Sports Med 9: 56-60, 1988.
19. O'Toole ML, Hiller WD, Roalstad MS, and Douglas PS. Hemolysis during triathlon races: its relation to race distance. Med Sci Sports Exerc 20: 272-275, 1988.
20. Poortmans JR and Haralambie G. Biochemical changes in a 100 km run: proteins in serum and urine. Eur J Appl Physiol 40: 245-254, 1979.
21. Raftos JE, Stewart IM, and Lovric VA. Supernatant hemoglobin determinations after prolonged blood storage. Pathology 18: 123-126, 1986.
22. Resina AL, Gatteschi Giamberardino MA, Rubenni MG, Trabassi E, and Troni MG. Comparison of RBC indices and serum iron parameters in trained runners and control subjects. Haematologica 73: 449-454, 1988.
23. Schmidt W, Maassen N, Trost F, and Boning D. Training induced effects on blood volume, erythrocyte turnover, and hemoglobin oxygen binding properties. Eur J Appl Physiol 57: 490-498, 1988.
24. 2 transport and iron status. Eur J Appl Physiol 60: 163-168, 1990.
25. Selby GB and Eichner ER. Endurance swimming, intravascular hemolysis, anemia, and iron depletion. New perspective on athletics anemia. Am J Med 81: 791-794, 1986.
26. Smith JA. Exercise, training and red blood cell turnover. Sports Med 19: 9-31, 1995.
27. Telford RD and Cunningham RB. Sex, sport and body-size dependency of hematology in highly trained athletes. Med Sci Sports Exerc 23: 788-794, 1991.
28. Weight LM. Sports anemia: does it exist? Sports Med 16: 1-4, 1993
29. Weight LM, Byrne MJ, and Jacobs P. Haemolytic effects of exercise. Clin Sci (Lond) 81: 147-152, 1991.