Adrenomedullin in synovial fluids from patients with rheumatoid arthritis inhibits interleukin 6 production from synoviocytes [2]

Annals of the Rheumatic Diseases

Volumn 62, Issue 1, 2003, Pages 82-83

  Nanke, Y ^a   Kotake, S ^a   Yonemoto, K ^a   Saito, S ^a   Tomatsu, T ^a   Kamatani, N ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; CYTOKINE; ENDOTHELIN 1; INTERLEUKIN 6;

ARTHRITIS; CASE REPORT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LETTER; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; SYNOVIAL FLUID LEVEL; SYNOVIOCYTE;

ADRENOMEDULLIN; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; OSTEOARTHRITIS; PEPTIDES; SYNOVIAL FLUID; SYNOVIAL MEMBRANE;

EID: 0037215240     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.62.1.82     Document Type: Letter

References (8)

1. Kitamura K, Kanagaw K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, et al. Adrenomedullin: A novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 1993;192:553-60.
2. Ishiyama Y, Kitamura K, Ichiki Y, Nakamura S, Kida O, Kangawa K, et al. Hemodynamic effects of a novel hypotensive peptide isolated from human adrenomedullin in rats. Eur J Pharmacol 1993;241:271-3.
3. Sugo S, Minamino N, Shoji H, Kangawa K, Kitamura K, Eto T, et al. Interleukin-1, tumor necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells. Biochem Biophys Res Commun 1995;207:25-32.
4. Kamoi H, Kanazawa H, Hirata K, Kurihara N, Yano Y, Otani S. Adrenomedullin inhibits the secretion of cytokine-induced neutrophil chemoattractant, a member of the interleukin-8 family, from rat alveolar macrophages. Biochem Biophys Res Commun 1995;211:1031-5.
5. Nanke Y, Kotake S, Shimamoto K, Hara M, Kamatani N. Raised plasma adrenomedullin in patients with systemic sclerosis complicated by pulmonary hypertension. Ann Rheum Dis 2000;59:493-4.
6. Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S, et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 1999;103:1345-52.
7. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
8. Kotake S, Sato K, Kim K, Takahashi N, Udagawa N, Nakamura I, et al. Interleukin-6 and soluble interlekin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation. J Bone Miner Res 1996;11:88-9.