Ultraviolet A radiation transiently disrupts gap junctional communication in human keratinocytes

American Journal of Physiology - Cell Physiology

Volumn 284, Issue 1 53-1, 2003, Pages

  Provost, Nicolas ^a   Moreau, Marielle ^a,c   Leturque, Armelle ^b   Nizard, Carine ^a,c  

^a PSL RESEARCH UNIVERSITY   (France)

^b INSERM   (France)

^c Parfums Christian Dior   (France)

Author keywords

Actin cytoskeleton; Connexin43; GJIC; Photoaging; Skin physiology

Indexed keywords

CONNEXIN 43; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ACTIN FILAMENT; AGING; ARTICLE; CELL COMMUNICATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; EPIDERMIS; GAP JUNCTION; HUMAN; HUMAN CELL; INTERNALIZATION; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RADIATION DOSE; SKIN CANCER; SKIN DEFECT; ULTRAVIOLET A RADIATION;

EID: 0037213266     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00205.2002     Document Type: Article

References (34)

1. Banrud H, Mikalsen SO, Berg K, and Moan J. Effects of ultraviolet radiation on intercellular communication in V79 Chinese hamster fibroblasts. Carcinogenesis 15: 233-239, 1994.
2. Banrud H, Moan J, and Berg K. Early induction of binucleated cells by ultraviolet A (UVA) radiation: A possible role of microfilaments. Photochem Photobiol 70: 199-205, 1999.
3. Brissette JL, Kumar NM, Gilula NB, Hall JE, and Dotto GP. Switch in gap junction protein expression is associated with selective changes in junctional permeability during keratinocyte differentiation. Proc Natl Acad Sci USA 91: 6453-6457, 1994.
4. Cooper CD, Solan JL, Dolejsi MK, and Lampe PD. Analysis of connexin phosphorylation sites. Methods 20: 196-204, 2000.
5. Denning MF, Wang Y, Nickoloff BJ, and Wrone-Smith T. Protein kinase C delta is activated by caspase-dependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes. J Biol Chem 273: 29995-30002, 1998.
6. Goodenough DA, Goliger JA, and Paul DL. Connexins, connexons, and intercellular communication. Annu Rev Biochem 65: 475-502, 1996.
7. Guo H, Acevedo P, Don Parsa F, and Bertram JS. Gap-junctional protein connexin 43 is expressed in dermis and epidermis of human skin: Differential modulation by retinoids. The Society for Investigative Dermatology 99: 460-467, 1992.
8. Haftek M, Kowalewski C, Mesnil M, Blaszczyk M, and Schmitt D. Internalization of gap junctions in benign familial pemphigus (Hailey-Hailey disease) and keratosis follicularis (Darier's disease). Br J Dermatol 141: 224-230, 1999.
9. Holder JW, Elmore E, and Barrett JC. Gap junction function and cancer. Cancer Res 53: 3475-3485, 1993.
10. Husoy T, Cruciani V, Sanner T, and Mikalsen SO. Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 fibroblasts: Minor role of protein kinase Cbeta 1 and mu. Carcinogenesis 22: 221-231, 2001.
11. Kumar NM and Gilula NB. The gap junction communication channel. Cell 84: 381-388, 1996.
12. Labarthe MP, Bosco D, Saurat JH, Meda P, and Salomon D. Upregulation of connexin 26 between keratinocytes of psoriatic lesions. J Invest Dermatol 111: 72-76, 1998.
13. Lampe PD and Lau AF. Regulation of gap junctions by phosphorylation of connexins. Arch Biochem Biophys 384: 205-215, 2000.
14. Maestrini E, Korge BP, Ocana-Sierra J, Calzolari E, Cambiaghi S, Scudder PM, Hovnanian A, Monaco AP, and Munro CS. A missense mutation in connexin26, D66H, causes mutilating keratoderma with sensorineural deafness (Vohwinkel's syndrome) in three unrelated families. Hum Mol Genet 8: 1237-1243, 1999.
15. Martyn KD, Kurata WE, Warn-Cramer BJ, Burt JM, Ten-Broek E, and Lau AF. Immortalized connexin43 knockout cell lines display a subset of biological properties associated with the transformed phenotype. Cell Growth Differ 8: 1015-1027, 1997.
16. Matsui MS and DeLeo VA. Induction of protein kinase C activity by ultraviolet radiation. Carcinogenesis 11: 229-234, 1990.
17. Matsui MS, Wang N, MacFarlane D, and DeLeo VA. Long-wave ultraviolet radiation induces protein kinase C in normal human keratinocytes. Photochem Photobiol 59: 53-57, 1994.
18. Mazzoleni G, Telo P, Camplani A, Tanganelli S, Monarca S, and Ragnotti G. Influence of the herbicide Linuron on growth rate and gap-junctional intercellular communication of cultured endothelial cells. J Environ Pathol Toxicol Oncol 13: 1-10, 1994.
19. Morliere P, Moysan A, Santus R, Huppe G, Maziere JC, and Dubertret L. UVA-induced lipid peroxidation in cultured human fibroblasts. Biochim Biophys Acta 1084: 261-268, 1991.
20. Poswig A, Wenk J, Brenneisen P, Wlaschek M, Hommel C, Quel G, Faisst K, Dissemond J, Briviba K, Krieg T, and Scharffetter-Kochanek K. Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation. J Invest Dermatol 112: 13-18, 1999.
21. Rafferty NS, Rafferty KA, and Zigman S. Comparative response to UV irradiation of cytoskeletal elements in rabbit and skate lens epithelial cells. Curr Eye Res 16: 310-319, 1997.
22. Reaume AG, de Sousa PA, Kulkarni S, Langille BL, Zhu D, Davies TC, Juneja SC, Kidder GM, and Rossant J. Cardiac malformation in neonatal mice lacking connexin43. Science 267: 1831-1834, 1995.
23. Rivedal E, Mollerup S, Haugen A, and Vikhamar G. Modulation of gap junctional intercellular communication by EGF in human kidney epithelial cells. Carcinogenesis 17: 2321-2328, 1996.
24. Salomon D, Masgrau E, Vischer S, Ullrich S, Dupont E, Sappino P, Saurat JH, and Meda P. Topography of mammalian connexins in human skin. J Invest Dermatol 103: 240-247, 1994.
25. Salomon D, Saurat JH, and Meda P. Cell-to-cell communication within intact human skin. J Clin Invest 82: 248-254, 1988.
26. Scharffetter-Kochanek K, Wlaschek M, Brenneisen P, Schauen M, Blaudschun R, and Wenk J. UV-induced reactive oxygen species in photocarcinogenesis and photoaging. Biol Chem 378: 1247-1257, 1997.
27. Simon AM and Goodenough DA. Diverse functions of vertebrate gap junctions. Trends Cell Biol 8: 477-483, 1998.
28. Tebbe B, Wu S, Geilen CC, Eberle J, Kodelja V, and Orfanos CE. L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-1α and IL-6 in cultured human keratinocytes in vitro. J Invest Dermatol 108: 302-306, 1997.
29. Temme A, Buchmann A, Gabriel HD, Nelles E, Schwarz M, and Willecke K. High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32. Curr Biol 7: 713-716, 1997.
30. VanSlyke JK and Musil LS. Analysis of connexin intracellular transport and assembly. Methods 20: 156-164, 2000.
31. Watt FM. Epidermal stem cells: Markers, patterning and the control of stem cell fate. Philos Trans R Soc Lond B Biol Sci 353: 831-837, 1998.
32. Wilgoss A, Leigh IM, Barnes MR, Dopping-Hepenstal P, Eady RA, Walter JM, Kennedy CT, and Kelsell DP. Identification of a novel mutation R42P in the gap junction protein beta-3 associated with autosomal dominant erythrokeratoderma variabilis. J Invest Dermatol 113: 1119-1122, 1999.
33. Zamansky GB, Nguyen U, and Chou IN. An immunofluorescence study of the effects of ultraviolet radiation on the organization of microfilaments, keratin intermediate filaments, and microtubules in human keratinocytes. Cell Motil Cytoskeleton 22: 296-306, 1992.
34. Zhang Y, Dong Z, Nomura M, Zhong S, Chen N, and Bode AM. Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation. J Biol Chem 28: 28, 2001.