Search for new urinary biochemical markers of collagen degradation in man

Clinica Chimica Acta

Volumn 327, Issue 1-2, 2003, Pages 81-86

  Roth, Marc ^a   Uebelhart, Daniel ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Collagen degradation; HPLC; Paget's disease of bone; Pyridinium crosslinks; Spinal cord injury; Urine

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; COLLAGEN; PYRIDINOLINE; DEOXYPYRIDINOLINE; PEPTIDE; PHENAZOPYRIDINE;

ADOLESCENT; ADULT; ARTICLE; CASE CONTROL STUDY; CHILD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; METABOLISM; MIDDLE AGED; PAGET BONE DISEASE; PARALYSIS; PRESCHOOL CHILD; SPINAL CORD INJURY; URINE; BIOASSAY; BIOCHEMISTRY; COLLAGEN DEGRADATION; CONTROLLED STUDY; CROSS LINKING; EXCRETION; EXTRACELLULAR MATRIX; PRIORITY JOURNAL; URINALYSIS;

ADOLESCENT; ADULT; AMINO ACIDS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN; HUMANS; MALE; MIDDLE AGED; OSTEITIS DEFORMANS; PARALYSIS; SPINAL CORD INJURIES;

EID: 0037212752     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(02)00338-8     Document Type: Article

References (8)

1. Vesper H.W., Demers L.M., Eastell R.et al. Assessment and recommendations on factors contributing to preanalytical variability of urinary pyridinoline and deoxypyridinoline. Clin. Chem. 48:2002;220-235.
2. Gineyts E., Garnero P., Delmas P. Urinary excretion of glucosyl-galactosyl pyridinoline: a specific biochemical marker of synovium degradation. Rheumatology. 40:2001;315-323.
3. Uebelhart D. Bone and Connective Tissue Metabolism in Spinal Cord Injury: A Comparative Study with Bed Rest Unloading. Thesis, University of Geneva, Faculty of Medicine; 1999.
4. Uebelhart D., Gineyts E., Chapuis M.C., Delmas P.D. Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease. Bone Miner. 8:1990;87-96.
5. Seibel M.J., Robins S.P., Bilezikian J.P. Urinary pyridinium crosslinks of collagen. Specific markers of bone resorption in metabolic bone disease. Trends Endocrinol. Metab. 3:1992;263-270.
6. Roth M., Uebelhart D. Determination of pyridinolines (free, peptide bound, glycosylated and total) in urine by high performance chromatography. Cells Mater. 7:1997;323-328.
7. Roth M., Uebelhart D. Liquid chromatography with fluorescence detection in the analysis of biological fluids. Anal. Lett. 33:2000;2353-2372.
8. Clemens J.D., Herrick M.V., Singer F.R., Eyre D.R. Evidence that serum NTx (collagen-type I N-telopeptides) can act as an immunochemical marker of bone resorption. Clin. Chem. 43:1997;2058-2063.