The design of prophylactic trials for HlV: The case of microbicides

Epidemiology

Volumn 14, Issue 1, 2003, Pages 80-83

  Stein, Zena A ^a,b,c   Myer, Landon ^a   Susser, Mervyn ^a,b  

^a Columbia University ^*  (United States)

^b Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^c NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; AGENTS USED INTRAVAGINALLY; PLACEBO; TOPICAL ANTIINFECTIVE AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; HIGH RISK POPULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION CONTROL; PRIORITY JOURNAL; PROPHYLAXIS; REVIEW; RISK BENEFIT ANALYSIS; VIRUS TRANSMISSION; ARTICLE; CONDOM; DISEASE TRANSMISSION; DRUG EFFECT; FEMALE; INTRAVAGINAL DRUG ADMINISTRATION; METHODOLOGY; RANDOMIZED CONTROLLED TRIAL; SEXUALLY TRANSMITTED DISEASE; UNITED STATES; VIROLOGY;

ADMINISTRATION, INTRAVAGINAL; ANTI-INFECTIVE AGENTS, LOCAL; CONDOMS, FEMALE; FEMALE; HIV; HIV INFECTIONS; HUMANS; PLACEBOS; RANDOMIZED CONTROLLED TRIALS; RESEARCH DESIGN; SEXUALLY TRANSMITTED DISEASES, VIRAL; UNITED STATES; VAGINAL CREAMS, FOAMS, AND JELLIES;

EID: 0037209186     PISSN: 10443983     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001648-200301000-00018     Document Type: Review

References (8)

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2. The Microbicide Initiative. Mobilization for Microbicides: The Decisive Decade. New York: The Rockefeller Foundation, 2002.
3. Roddy RE, Zekeng L, Ryan KA, Tamoufe U, Tweedy KG. Effect of nonoxynol-9 gel on urogenital gonorrhea and chlamydial infection: a randomized controlled trial. JAMA 2002;287:1117-1122.
4. Richardson BA. Nonoxynol-9 as a vaginal microbicide for prevention of sexually transmitted infections: it's time to move on. JAMA 2002;287:1171-1172.
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6. WHO/CONRAD. Technical Consultation on Nonoxynol-9. Summary Report. Geneva: World Health Organization, 2001.
7. Mill JS. A System of Logic. London: Parker, Son and Bewin, 1856.
8. Susser M. What is a cause and how do we know one? A grammar for pragmatic epidemiology. Am J Epidemiol 1991;133:635-648.