Frontotemporal dementia with cerebral intraneuronal ubiquitin-positive inclusions but lacking lower motor neuron involvement

Acta Neuropathologica

Volumn 105, Issue 1, 2003, Pages 81-85

  Yaguchi, Masamitsu ^a   Okamoto, Koichi ^a   Nakazato, Yoichi ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Frontotemporal dementia; Motor neuron disease inclusion dementia; Tau; Ubiquitin

Indexed keywords

ALPHA SYNUCLEIN; TAU PROTEIN; UBIQUITIN;

ADULT; ANTERIOR HORN CELL; ARGYROPHILIA; ARTICLE; BRAIN DEGENERATION; BRAIN NERVE CELL; BRAIN SPONGIOSIS; CASE REPORT; CELL INCLUSION; CELL LOSS; DENTATE GYRUS; FEMALE; FRONTAL CORTEX; FRONTOTEMPORAL DEMENTIA; GLIA; GOLGI COMPLEX; HUMAN; HYPOGLOSSAL NUCLEUS; IMMUNOHISTOCHEMISTRY; MENTAL DISEASE; MOTOR CORTEX; MOTOR NEURON DISEASE; PRIORITY JOURNAL; PUTAMEN; PYRAMIDAL NERVE CELL; PYRAMIDAL TRACT; TEMPORAL CORTEX; BRAIN; DEMENTIA; METABOLISM; MIDDLE AGED; NERVE CELL; PATHOLOGY; ULTRASTRUCTURE;

BRAIN; DEMENTIA; FEMALE; HUMANS; INCLUSION BODIES; MIDDLE AGED; NEURONS; UBIQUITIN;

EID: 0037209111     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-002-0611-z     Document Type: Article

References (26)

1. Bigio EH, Lipton AM, Yen SH, Huttot ML, Baker M, Nachraju P, White CL, Davies P, Lin W, Dickson DW (2001) Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia. J Neuropathol Exp Neurol 60: 328-341
2. Foster NL, Wilhelmsen K, Sima AAF., Jones MZ, D'Amato CJ, Gilman S (1997) Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Ann Neurol 41:706-715
3. Gonatas NK, Stieber A, Mourelatos Z, Chen Y, Gonatas JO, Appel SH, Hays AP, Hickey WF, Hauw JJ (1992) Fragmentation or the Golgi apparatus or motor neurons in amyotrophic lateral sclerosis. Am J Pathol 140:731-737
4. Holten JL, Révész T, Crooks R, Scaravilli F (2002) Evidence for pathological involvement of the spinal cord in motor neuron disease-inclusion dementia. Acta Neuropathol 103:221-227
5. Ikeda K, Akiyama H, Hafa C, Haga C, Kondo H, Arima K, Oda T (1994) Argyrophilic thread-like structure in corticobasal degeneration and supranuclear palsy. Neurosci Lett 174:157-159
6. Iseki E, Li F, Odawara T, Hino H, Suzuki K, Kosaka K, Akiyama H, Ikeda K, Kato M (1998) Ubiquitin-immunohistochemical investigation of atypical Pick's disease without Pick bodies. J Neurol Sci 159:194-201
7. Jackson M, Lennox G, Lowe J (1996) Motor neuron disease-inclusion dementia. Neurodegeneration 5:339-350
8. Kawashima T, Kikuchi H, Takita M, Takita M, Doh-ura K, Ogomori K, Oda M, Iwaki T (1998) Skein-like inclusions in the neostriatum from a case of amyotrophic lateral sclerosis with dementia. Acta Neuropathol 96:541-545
9. Kövari E, Leuba G, Savios A, Saini K, Anastasiu R, Miklossy J, Bouras C (2000) Familial frontotemporal dementia with ubiquitin inclusion bodies and without motor neuron disease. Acta Neuropathol 100:421-426
10. Lowe J, Aldridge F, Lennox G, Doherty F, Jefferson D, Landon M, Mayer RJ (1989) Inclusion bodies in motor cortex and brainstem of patients with motor neuron disease are detected by immunocytochemical localization of ubiquitin. Neurosci Lett 105:7-13
11. Lowe J, Graham Lennox, Leigh PN (1997) Motor neuron disorders. In: Graham DI, Lantos PL (eds) Greenfield's neuropathology, vol 2, 6th edn. Arnold, London, pp 320-330
12. Mourelatos Z, Yachnis A, Rorke L, Rorke L, Mikol J, Gonatas NK (1993) The Golgi apparatus of motor neurons in amyotrophic lateral sclerosis. Ann Neurol 33:608-615
13. Murayama S, Inoue K, Kwakami H, Bouldin TW, Suzuki K (1991) A unique pattern of astrocytosis in the primary motor area in amyotrophic lateral sclerosis. Acta Neuropathol 82: 456-461
14. Nishimura M, Tomimoto H, Suenaga T, et al. (1995) Immunohistochemical characterization of glial fibrillary tangles in Alzheimer's disease brain. Am J Pathol 146:1052-1058
15. Noda K, Katayama S, Watanabe C, Yamamura Y, Nakamura S (1999) Gallyas- and tau-positive glial structures in motor neuron disease with dementia. Clin Neuropathol 18:218-225
16. Okamoto K, Murakami N, Kusaka H, Yoshida M, Hashizume Y, Nakazato Y, Matsubara E, Hirai W (1992) Ubiquitin-positive intraneuronal inclusions in the extra-motor cortices of presenile dementia patients with motor neuron disease. J Neurol 239:426-430
17. Parent A (1996) Cerebral cortex. In: Parent A (ed) Carpenter's human neuroanatomy, 9th edn. Williams & Wilkins, Baltimore, pp 864-936
18. Rossor MN, Revesz T, Lantos PL, Warrington EK (2000) Semantic dementia with ubiquitin-positive tau-negative inclusion bodies. Brain 123:267-276
19. Sakurai A, Okamoto K, Fujita Y, Nakazato Y, Wakabayashi K, Takahashi H, Gonatas NK (2000) Fragmentation of the Golgi apparatus of the ballooned neurons in patients with corticobasal degeneration and Creutzfeldt-Jakob disease. Acta Neuropathol 100:270-274
20. Sasaki S, Murayama S (1994) Immunocytochemical and ultrastructual studies of the motor cortex in amyotrophic lateral sclerosis. Acta Neuropathol 87:578-585
21. The Lund and Manchester Groups(1994) Consensus statement, Clinical and neuropathological criteria for fronto-temporal dementia. J Neurol Neurosurg Psychiatry 57:416-418
22. Tsuchiya K, Ikeda K, Haga C, Kobayashi T, Morimatsu Y, Nakano I, Matsushita M (2001) Atypical amyotrophic lateral sclerosis with dementia mimicking frontal Pick's disease: a report of an autopsy case with a clinical course of 15 years. Acta Neuropathol 101:625-630
23. Uchihara T, Tsuchiya K, Nakamura A, Ikeda K (2000) appearance of tau-2 immunoreactivity in glial cells in human brain with cerebral infarction. Neurosci Lett 286:99-102
24. Uchihara T, Sato T, Suzuki H, Ikeda K, Akiyama H, Takatori T (2001) Bunina body in frontal lobe dementia without clinical manifestations of motor neuron disease. Acta Neuropathol 101: 281-284
25. Wightman G, Anderson VER, Martin J, Swash M, Anderton BH, Neary D, Mann D, Luthert P, Leigh PN (1992) Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia. Neurosci Lett 139:269-274
26. Yasuhara O, Matsuo A, Tooyama I, Kimura H, McGeer EG, McGeer PL (1995) Pick's disease immunohistochemistry: the alterations and Alzheimer's disease comparison. Acta Neuropathol 89:322-330